Results 1 to 10 of about 8,666 (209)
Frontiers in Immunology, 2022 Melanization in the hemolymph of arthropods is a conserved defense strategy against infection by invading pathogens. Numerous plant viruses are persistently transmitted by insect vectors, and must overcome hemolymph melanization.
Ruonan Zhang +6 more
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Frontiers in Immunology, 2023 Cellular encapsulation associated with melanization is a crucial component of the immune response in insects, particularly against larger pathogens.
Tomas Dolezal
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Melanization in
mBio, 2020 The fungal human pathogen Cryptococcus neoformans undergoes melanization in response to nutrient starvation and exposure to exogenous melanin precursors.
Radames J. B. Cordero +2 more
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PLoS Pathogens, 2020 The arthropod melanization immune response is activated by extracellular protease cascades predominantly comprised of CLIP-domain serine proteases (CLIP-SPs) and serine protease homologs (CLIP-SPHs).
Gregory L Sousa +3 more
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Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera. [PDF]
PLoS Pathogens, 2017 Melanization, an important insect defense mechanism, is mediated by clip-domain serine protease (cSP) cascades and is regulated by serpins. Here we show that proteolytic activation of prophenoloxidase (PPO) and PO-catalyzed melanization kill the ...
Chuanfei Yuan +7 more
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Layers of immunity: Deconstructing the Drosophila effector response [PDF]
eLifeThe host innate immune response relies on the cooperation of multiple defense modules. In insects and other arthropods, which have only innate immune mechanisms, four main immune-specific modules have been described in the defense against microbial ...
Faustine Ryckebusch +5 more
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Unculturable bacteria exploit a secretory protein to antagonize insect melanization for persistent infection [PDF]
mBioPhloem-inhabiting unculturable bacterial pathogens are persistently transmitted by insect vectors. However, how they evade insect immune responses to ensure persistent transmission remains unknown. The important melanization immune response in insects is
You Li +5 more
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Encapsulation and Melanization Are Not Correlated to Successful Immune Defense Against Parasitoid Wasps in Drosophila melanogaster [PDF]
CellsParasitoid elimination in Drosophila melanogaster involves special hemocytes, called lamellocytes, which encapsulate the eggs or larvae of the parasitoid wasps. The capsules are melanized, and metabolites of the melanization reaction may play a potential
Lilla B. Magyar +2 more
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PLoS ONE, 2022 Cutibacterium acnes is a pathogenic bacterium that cause inflammatory diseases of the skin and intervertebral discs. The immune activation induced by C. acnes requires multiple cellular responses in the host.
Yasuhiko Matsumoto +2 more
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Frontiers in Cell and Developmental Biology, 2021 The Asian tiger mosquito, Aedes albopictus, is one of the most serious public health pests, which can transmit various vector-borne diseases. Eggs from this mosquito species become dark black shortly after oviposition and exhibit high desiccation ...
Mi Young Noh +4 more
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