Results 11 to 20 of about 8,666 (209)

Hemocyte Changes During Immune Melanization in Bombyx Mori Infected with Escherichia coli

Insects, 2019
Hemolymph melanization is a conserved immune response in insects and other arthropods. However, the physiological process of the hemolymph system in the melanization response is hardly studied.
Tian Li, Dengfeng Yan, Xiaohui Wang, Liang Zhang, Ping Chen   +4 more
doaj   +2 more sources

The yellow gene influences Drosophila male mating success through sex comb melanization

eLife, 2019
Drosophila melanogaster males perform a series of courtship behaviors that, when successful, result in copulation with a female. For over a century, mutations in the yellow gene, named for its effects on pigmentation, have been known to reduce male ...
Jonathan H Massey, Daayun Chung, Igor Siwanowicz, David L Stern, Patricia J Wittkopp   +4 more
doaj   +2 more sources

The Role of Testosterone and Gibberellic Acid in the Melanization of Cryptococcus neoformans

Frontiers in Microbiology, 2020
Cryptococcus neoformans, a spore-producing pathogenic yeast, affects immunocompromised individuals causing meningoencephalitis. Once C. neoformans is introduced via the respiratory tract, it is engulfed by macrophages and other phagocytes.
Jamila S. Tucker, Jamila S. Tucker, Tiffany E. Guess, Tiffany E. Guess, Erin E. McClelland   +4 more
doaj   +2 more sources

Bmserpin2 Is Involved in BmNPV Infection by Suppressing Melanization in Bombyx mori

Insects, 2019
Melanization, an important defense response, plays a vital role in arthropod immunity. It is mediated by serine proteases (SPs) that convert the inactive prophenoloxidase (PPO) to active phenoloxidase (PO) and is tightly regulated by serine protease ...
Shahzad Toufeeq, Jie Wang, Shang-Zhi Zhang, Bing Li, Pei Hu, Lin-Bao Zhu, Ling-Ling You, Jia-Ping Xu   +7 more
doaj   +2 more sources

An evolutionarily conserved serine protease network mediates melanization and Toll activation in Drosophila

Science Advances, 2023
Melanization and Toll pathway activation are essential innate immune mechanisms in insects, which result in the generation of reactive compounds and antimicrobial peptides, respectively, to kill pathogens.
Tisheng Shan, Yang Wang, Krishna Bhattarai, Haobo Jiang   +3 more
semanticscholar   +1 more source

Melanization slows the rapid movement of fungal necromass carbon and nitrogen into both bacterial and fungal decomposer communities and soils

mSystems, 2023
Microbial necromass contributes significantly to both soil carbon (C) persistence and ecosystem nitrogen (N) availability, but quantitative estimates of C and N movement from necromass into soils and decomposer communities are lacking.
François Maillard, Talia J Michaud, C. See, L. C. DeLancey, S. Blazewicz, Jeffrey A. Kimbrel, J. Pett‐Ridge, P. Kennedy   +7 more
semanticscholar   +1 more source

The endosymbiont Spiroplasma poulsonii increases Drosophila melanogaster resistance to pathogens by enhancing iron sequestration and melanization

bioRxiv, 2023
Facultative endosymbiotic bacteria, such as Wolbachia and Spiroplasma species, are commonly found in association with insects and can dramatically alter their host physiology.
Alexandra Hrdina, Marina Serra Canales, Aranzazu Arias-Rojas, Dagmar Frahm, I. Iatsenko   +4 more
semanticscholar   +1 more source

Insight into the structural hierarchy of the protease cascade that regulates the mosquito melanization response

bioRxiv, 2023
Serine protease cascades regulate important insect immune responses, including melanization and Toll pathway activation. In the context of melanization, central components of these cascades are clip domain serine proteases (CLIPs) including the catalytic,
S. Saab, Xiufeng Zhang, Suheir Zeineddine, Bianca Morejón, K. Michel, M. Osta   +5 more
semanticscholar   +1 more source

Galleria mellonella immune melanization is fungicidal during infection

Communications Biology, 2022
A key component of the insect immune response is melanin production, including within nodules, or aggregations of immune cells surrounding microbes. Melanization produces oxidative and toxic intermediates that limit microbial infections.
Daniel F. Q. Smith, Q. Dragotakes, Madhura Kulkarni, J. Hardwick, A. Casadevall   +4 more
semanticscholar   +1 more source

Melanization of Candida auris Is Associated with Alteration of Extracellular pH

bioRxiv, 2022
Candida auris is a recently emerged global fungal pathogen, which causes life-threatening infections, often in healthcare settings. C. auris infections are worrisome because the fungus is often resistant to multiple antifungal drug classes.
Daniel F. Q. Smith, Nathan J. Mudrak, Daniel Zamith-Miranda, L. Honorato, L. Nimrichter, Christine Chrissian, Barbara J Smith, G. Gerfen, R. Stark, J. Nosanchuk, A. Casadevall   +10 more
semanticscholar   +1 more source