Results 1 to 10 of about 2,739 (191)

Melanization in Cryptococcus neoformans Requires Complex Regulation

mBio, 2020
The fungal human pathogen Cryptococcus neoformans undergoes melanization in response to nutrient starvation and exposure to exogenous melanin precursors.
Radames J. B. Cordero, Emma Camacho, Arturo Casadevall   +2 more
doaj   +2 more sources

Hemocyte Changes During Immune Melanization in Bombyx Mori Infected with Escherichia coli

Insects, 2019
Hemolymph melanization is a conserved immune response in insects and other arthropods. However, the physiological process of the hemolymph system in the melanization response is hardly studied.
Tian Li, Dengfeng Yan, Xiaohui Wang, Liang Zhang, Ping Chen   +4 more
doaj   +2 more sources

Role of Cln1 during melanization of Cryptococcus neoformans [PDF]

Frontiers in Microbiology, 2015
Cryptococcus neoformans is an opportunistic fungal pathogen that has several well-described virulence determinants. A polysaccharide capsule and the ability to produce melanin are among the most important.
Rocío eGarcía-Rodas, Nuria eTrevijano-Contador, Elvira eRomán, Guilhem eJanbon, Frederique eMoyrand, Jesus ePla, Arturo eCasadevall, Oscar eZaragoza   +7 more
doaj   +2 more sources

Acute melanization of silkworm hemolymph by peptidoglycans of the human commensal bacterium Cutibacterium acnes.

PLoS ONE, 2022
Cutibacterium acnes is a pathogenic bacterium that cause inflammatory diseases of the skin and intervertebral discs. The immune activation induced by C. acnes requires multiple cellular responses in the host.
Yasuhiko Matsumoto, Eri Sato, Takashi Sugita   +2 more
doaj   +2 more sources

Nucleoprotein of a Rice Rhabdovirus Serves as the Effector to Attenuate Hemolymph Melanization and Facilitate Viral Persistent Propagation in its Leafhopper Vector

Frontiers in Immunology, 2022
Melanization in the hemolymph of arthropods is a conserved defense strategy against infection by invading pathogens. Numerous plant viruses are persistently transmitted by insect vectors, and must overcome hemolymph melanization.
Ruonan Zhang, Xiao-Feng Zhang, Yunhua Chi, Yuanyuan Xu, Hongyan Chen, Zhongxin Guo, Taiyun Wei   +6 more
doaj   +1 more source

Antarctolichenia onofrii gen. nov. sp. nov. from Antarctic Endolithic Communities Untangles the Evolution of Rock-Inhabiting and Lichenized Fungi in Arthoniomycetes

Journal of Fungi, 2021
Microbial endolithic communities are the main and most widespread life forms in the coldest and hyper-arid desert of the McMurdo Dry Valleys and other ice-free areas across Victoria Land, Antarctica.
Lucia Muggia, Claudia Coleine, Roberto De Carolis, Agnese Cometto, Laura Selbmann   +4 more
doaj   +1 more source

The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae.

PLoS Pathogens, 2020
The arthropod melanization immune response is activated by extracellular protease cascades predominantly comprised of CLIP-domain serine proteases (CLIP-SPs) and serine protease homologs (CLIP-SPHs).
Gregory L Sousa, Ritika Bishnoi, Richard H G Baxter, Michael Povelones   +3 more
doaj   +1 more source

How to eliminate pathogen without killing oneself? Immunometabolism of encapsulation and melanization in Drosophila

Frontiers in Immunology, 2023
Cellular encapsulation associated with melanization is a crucial component of the immune response in insects, particularly against larger pathogens.
Tomas Dolezal
doaj   +1 more source

Inhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera. [PDF]

PLoS Pathogens, 2017
Melanization, an important insect defense mechanism, is mediated by clip-domain serine protease (cSP) cascades and is regulated by serpins. Here we show that proteolytic activation of prophenoloxidase (PPO) and PO-catalyzed melanization kill the ...
Chuanfei Yuan, Longsheng Xing, Manli Wang, Xi Wang, Mengyi Yin, Qianran Wang, Zhihong Hu, Zhen Zou   +7 more
doaj   +1 more source

Molecular Evolution and Developmental Expression of Melanin Pathway Genes in Lepidoptera

Frontiers in Ecology and Evolution, 2020
Pigmentation is involved in a wide array of biological functions across insect orders, including body patterning, thermoregulation, and immunity. The melanin pathway, in particular, has been characterized in several species.
Muktai Kuwalekar, Riddhi Deshmukh, Ajay Padvi, Krushnamegh Kunte   +3 more
doaj   +1 more source