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Functional coupling between MC4R and Kir7.1 contributes to clozapine-induced weight gain in female mice. [PDF]
Li L +13 more
europepmc +1 more source
Current and forthcoming pharmacotherapies for adolescent obesity: Evidence-based review. [PDF]
Fuentes-Mendoza JM +9 more
europepmc +1 more source
MC4R-related monogenic obesity in children: insights from 2 cases. [PDF]
Shanmugam D +5 more
europepmc +1 more source
Erratum: A Review of Current Trends with Type 2 Diabetes Epidemiology, Aetiology, Pathogenesis, Treatments and Future Perspectives [Corrigendum]. [PDF]
europepmc +1 more source
Fish melanocortin system [PDF]
Melanocortin signalling is mediated by binding to a family of G protein-coupled receptors that positively couple to adenylyl cyclase. Tetrapod species have five melanocortin (MC(1)-MC(5)) receptors. The number of receptors varies in fish, zebrafish, for example, having six melanocortin receptors, with two copies of the melanocortin MC(5) receptor ...
Josep Rotllant +2 more
exaly +4 more sources
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American Journal of Physiology-Endocrinology and Metabolism, 2003
The melanocortin system consists of melanocortin peptides derived from the proopiomelanocortin gene, five melanocortin receptors, two endogenous antagonists, and two ancillary proteins. This review provides an abbreviated account of the basic biochemistry, pharmacology, and physiology of the melanocortin system and highlights progress made in four ...
Ira, Gantz, Tung M, Fong
openaire +2 more sources
The melanocortin system consists of melanocortin peptides derived from the proopiomelanocortin gene, five melanocortin receptors, two endogenous antagonists, and two ancillary proteins. This review provides an abbreviated account of the basic biochemistry, pharmacology, and physiology of the melanocortin system and highlights progress made in four ...
Ira, Gantz, Tung M, Fong
openaire +2 more sources
Brain Melanocortin Receptors: From Cloning to Function
The cloning of brain melanocortin (MC) receptors, the mapping of their expression pattern and the identification of MC receptor selective ligands have opened a new avenue towards elucidating the role of the melanocortin system in the brain.
Roger A H Adan +2 more
exaly +2 more sources

