Results 111 to 120 of about 60,692 (262)

Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies. [PDF]

, 2013
Second-generation antipsychotic exposure, in both children and adults, carries significant risk for excessive weight gain that varies widely across individuals.
Aman, MG, Arnold, LE, Handen, B, Johnson, C, Lecavalier, L, McCracken, JT, McDougle, CJ, Nurmi, EL, Posey, DJ, Research Units on Pediatric Psychopharmacology Autism Network, Ritz, L, Scahill, LL, Spilman, SL, Stigler, KA, Sukhodolsky, DG, Tierney, E, Vitiello, B, Whelan, F   +17 more
core   +1 more source

From Permits to Samples: Addressing Key Challenges for High‐Quality Reference Genome Generation in Europe

Molecular Ecology Resources, Volume 26, Issue 2, February 2026.
ABSTRACT High‐quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample‐handling procedures leading up to nucleic acid ...
Katja Reichel, Jaakko Pohjoismäki, Jonas J. Astrin, Astrid Böhne, Chiara Bortoluzzi, Elena Bužan, Javier del Campo, Claudio Ciofi, Camilla B. Di‐Nizo, Pradeep K. Divakar, Carola Greve, Vladimír Hampl, Leon Hilgers, Veronika N. Laine, Jennifer A. Leonard, Jesus Lozano‐Fernandez, Lada Lukić Bilela, Camila J. Mazzoni, Ann M. McCartney, José Melo‐Ferreira, Rita Monteiro, Rebekah A. Oomen, Martina Pavlek, João Pimenta, Michal Rindos, Ole Seehausen, Andrii Tarieiev, Salvatore Tomasello, Olga Vinnere Pettersson, Robert M. Waterhouse, Alexandra A.‐T. Weber, Oleksandr Zinenko, Christian de Guttry   +32 more
wiley   +1 more source

Melanocortin-1 receptor ( MC1R ) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic nevi [PDF]

, 2020
Neus Calbet‐Llopart, Mirella Pascini‐Garrigos, Gemma Tell‐Martí, Míriam Potrony, Vanessa Martins da Silva, Alicia Barreiro, Susana Puig, Guillaume Captier, Isabelle James, N. Dégardin, Cristina Carrera, Josep Malvehy, Heather Etchevers, Joan Anton Puig‐Butillé   +13 more
openalex   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

Funktionelle Konsequenzen von Mutationen im Melanocortin-4-Rezeptorgen bei adipösen Kindern und Jugendlichen [PDF]

, 2006
Der Melanocortin-4-Rezeptor spielt eine zentrale Rolle in der Gewichtsregulation, er vermittelt (indirekt) die anorexigenen Effekte des Leptin, indem er nach Aktivierung eine Einstellung der Nahrungsaufnahme und eine Erhöhung der Stoffwechselrate ...
Gudermann, Thomas (Prof. Dr.), Hohmann, Sarah Hortense   +1 more
core   +1 more source

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source

Polymorphisms in the Melanocortin-1 Receptor (Mc1R) Gene in Vitiligo

Balkan Medical Journal, 2012
Objective: Vitiligo is a progressive skin pigmentation disorder, which may be acquired or hereditary, frequently seen, and may influence every age group. The melanocortin 1 receptor (MC1R) gene is a major determinant of human pigmentation.
Eylem Acar, Gökay Bozkurt, Adnan Görgülü   +2 more
doaj  

Nesfatin-1, a unique regulatory neuropeptide of the brain [PDF]

, 2012
Nesfatin-1, a newly discovered NUCB2-derived satiety neuropeptide is expressed in several neurons of forebrain, hindbrain, brainstem and spinal cord. This novel anorexigenic substance seems to play an important role in hypothalamic pathways regulating ...
Bajor, Grzegorz, Czajkowska, Beata, Kostro, Karol, Krzystanek, Marek, Palasz, Artur, Wiaderkiewicz, Ryszard, Worthington, John   +6 more
core   +1 more source

Topiramate Enhances GABAergic Tone to Orexigenic Neuropeptide Y/Agouti‐Related Peptide (NPY/AgRP) Neurons

Obesity, Volume 34, Issue 1, Page 175-187, January 2026.
ABSTRACT Objective Topiramate is a medication used off‐label, or in combination with phentermine, for the management of obesity. However, its mechanism of action remains elusive. As many obesity medications target the brain, we aimed to determine if topiramate influences the activity of hypothalamic melanocortin neurons known to regulate energy balance.
Moein Minbashi Moeini, Olivier Lavoie, Alexandre Caron, Kevin W. Williams, Natalie J. Michael   +4 more
wiley   +1 more source

The role of insulin receptor substrate 2 in hypothalamic and beta cell function [PDF]

, 2005
Insulin receptor substrate 2 (Irs2) plays complex roles in energy homeostasis. We generated mice lacking Irs2 in beta cells and a population of hypothalamic neurons (RIPCreIrs2KO), in all neurons (NesCreIrs2KO), and in proopiomelanocortin neurons ...
Al-Qassab, H, Ashford, MLJ, Barsh, GS, Batterham, RL, Bedford, DC, Bell, JD, Choudhury, AI, Claret, M, Clements, M, Diakonov, I, Heffron, H, Hisadome, K, MacColl, G, Moosajee, V, Selman, C, Simmgen, M, Smith, MA, Speakman, JR, Withers, DJ, Xu, AW   +19 more
core