Hematopoietic-specific melanocortin 1 receptor signaling protects against nephrotoxic serum nephritis and mediates the beneficial effect of melanocortin therapy. [PDF]
Kidney Int, 2023 Guan X +5 more
europepmc +1 more source
Podocyte Melanocortin 1 Receptor Mediated Signaling
, 2015 Treatment of patients with nephrotic syndrome (NS) is currently unspecific and directed at ameliorating the symptoms rather than eliminating the cause. NS is actually a multitude of glomerular diseases characterized by poorly understood disease mechanisms and symptoms that include proteinuria, hypoalbuminemia and edema.
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Dersimelagon, a novel oral melanocortin 1 receptor agonist, demonstrates disease-modifying effects in preclinical models of systemic sclerosis. [PDF]
Arthritis Res Ther, 2022 Kondo M +12 more
europepmc +1 more source
Functional divergence of the pigmentation gene melanocortin-1 receptor (MC1R) in six endemic Macaca species on Sulawesi Island. [PDF]
Sci Rep, 2022 Yan X +7 more
europepmc +1 more source
Genetic diversity of the melanocortin-1 receptor in an admixed population of Rio de Janeiro: Structural and functional impacts of Cys35Tyr variant. [PDF]
PLoS One, 2022 Neitzke-Montinelli V +4 more
europepmc +1 more source
Melanocortin 1 Receptor Deficiency in Hematopoietic Cells Promotes the Expansion of Inflammatory Leukocytes in Atherosclerotic Mice. [PDF]
Front Immunol, 2021 Kadiri JJ +5 more
europepmc +1 more source
Melanocortin-1 Receptor Positively Regulates Human Artery Endothelial Cell Migration
Cellular Physiology and Biochemistry, 2019 Federica Saporiti +6 more
doaj +1 more source
Melanocortin 1 receptor is dispensable for acute stress induced hair graying in mice. [PDF]
Exp Dermatol, 2021 Zhang B +6 more
europepmc +1 more source
Analysis of the melanocortin receptor 1 (MC1R) gene in Sicilian goat breeds
Italian Journal of Animal Science, 2010 L. Fontanesi +5 more
doaj +1 more source