Results 131 to 140 of about 58,672 (263)

Metabolic and appetitive regulation of adipocyte mass during treatment of obesity

Journal of Internal Medicine, Volume 299, Issue 1, Page 66-78, January 2026.
Abstract Adipose mass is homeostatically maintained within a narrow range despite fluctuations in daily calorie intake and activity levels. Constituting an adipose mass “set point,” this homeostatic regulation includes sensing mechanisms in the form of hormones reflecting caloric intake that serve as mediators of appetitive behaviors and adipose mass ...
Jonathan Q. Purnell, Carel W. Le Roux
wiley   +1 more source

Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor [PDF]

, 2019
Rana N. Özdeşlik, Lauren E. Olinski, Melissa M. Trieu, Daniel D. Oprian, Elena Oancea   +4 more
openalex   +1 more source

Genetics of Severe Obesity [PDF]

, 2018
Purpose of Review This review aims to present current information on genes underlying severe obesity, with the main emphasis on the three genes LEP, LEPR and MC4R.
Fairbrother, U, Kidd, E, Malagamuwa, T, Walley, AJ   +3 more
core   +1 more source

Pigments, Chromatophore Structure, and Gene Expression Underlying Colour Polytypy of a Panamanian Poison Frog

Molecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Colour polytypism represents an example of phenotypic diversification shaped by genetic divergence and ecological pressures. Poison frogs of the genus Oophaga (Dendrobatidae) are highly polytypic in coloration, making them an ideal system for investigating the genetic and physiological basis of colour variation.
Vasiliki Mantzana‐Oikonomaki, Giselle Tamayo‐Castillo, Víctor Vásquez‐Cháves, Abel Mora‐Machado, William J. Zamora Ramirez, Roberto Ibáñez, Heike Pröhl, Ariel Rodríguez   +7 more
wiley   +1 more source

Cutaneous Malignant Melanoma Incidences Analyzed Worldwide by Skin Type over Advancing Age of Males and Females: Evidence Estrogen and Androgenic Hair are Risk Factors [PDF]

, 2017
We previously analyzed cutaneous malignant melanoma (CMM) incidences worldwide by sex, age, and Fitzpatrick skin type over time (1955-2007) and found only European-ancestry populations have exponential increasing incidences and about a 2-log increase in ...
Godar, Dianne E., Merrill, Stephen, Subramanian, Madhan   +2 more
core   +1 more source

Association Between Physical Activity and Indicators of Overweight/Obesity and Metabolically Unhealthy Obesity Risk in Children and Adolescents: A Systematic Review of Prospective Epidemiological Studies and Randomized Controlled Trials in Western Countries

Obesity Reviews, Volume 27, Issue 1, Page 1-28, January 2026.
ABSTRACT This systematic review examined the etiologic association between physical activity (PA) and indicators of childhood overweight/obesity (OV/OB) and metabolically unhealthy obesity (MUO) risk. Original peer‐reviewed English reports published between January 01, 2013, and June 30, 2024, were retrieved from MEDLINE and Scopus.
Michael Georgoulis, Ismini Grapsa, Giannis Arnaoutis, Vasiliki Bountziouka, Alexandra Karachaliou, Georgios Saltaouras, Eirini Bathrellou, Mary Yannakoulia, George Dimitrakopoulos, Meropi D. Kontogianni   +9 more
wiley   +1 more source

A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties

Skin Research and Technology, Volume 32, Issue 1, January 2026.
ABSTRACT Background With increasing life expectancy, the aging population, particularly in Asia, is expanding rapidly. Combined with intense year‐round ultraviolet exposure, this accelerates skin aging. Male skin also exhibits distinct aging characteristics.
Mingkwan Na Takuathung, Kantirat Yaja, Jakkrit Aisara, Preeyaporn Klinjan, Pannita Anek, Ratchanon Inpan, Tattiya Kantasa, Jeeraporn Chitphan, Kankanit Yeerong, Supanimit Teekachunhatean, Nut Koonrungsesomboon   +10 more
wiley   +1 more source

The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands. [PDF]

Int J Mol Sci, 2023
Ericson MD, Freeman KT, LaVoi TM, Donow HM, Santos RG, Giulianotti MA, Pinilla C, Houghten RA, Haskell-Luevano C.   +8 more
europepmc   +1 more source

Does Obesity Induce Resistance to the Long-Term Cardiovascular and Metabolic Actions of Melanocortin 3/4 Receptor Activation? [PDF]

, 2005
Alexandre A. da Silva, Jay J. Kuo, Lakshmi S. Tallam, Jiankang Liu, John E. Hall   +4 more
openalex   +1 more source

Natural dual inhibitor isorhamnetin-3-O-neohespeidoside targets tyrosinase and MC1R for skin pigmentation management

Scientific Reports
Skin pigmentation disorders involve complex biological regulation, with tyrosinase (TYR) and melanocortin 1 receptor (MC1R) serving as key therapeutic targets.
Rongrong Deng, Shiqian Zheng, Shengjun Xie, Gengjiu Huang, Zhiwen Ou, Zhibin Shen   +5 more
doaj   +1 more source