Results 171 to 180 of about 34,268 (231)

Recent developments in GPCR signalling in appetite regulation. [PDF]

Biosci Rep
Brittain HR, Gorvin CM.
europepmc   +1 more source

Examining a central mechanism whereby undernutrition inhibits GnRH secretion via KNDy neurons. [PDF]

J Reprod Dev
Nestor CC, Kennedy A.
europepmc   +1 more source

An exploratory microarray analysis of estrogen-mediated gene expression in central pathways that control energy balance in female rats (Rattus norvegicus). [PDF]

BMC Res Notes
Lang H, Burch K, Sloan D.
europepmc   +1 more source

Genetic variants in the leptin-melanocortin pathway and their joint effects with physical activity and sleep duration on risk of childhood obesity. [PDF]

PLoS One
Liang X, Pan S, Ji J, Deng Y, Chen M, Huang Z, Deng J, Chen M, Xiong T, Liang J, Liu L.   +10 more
europepmc   +1 more source

Investigating the role of melanocortinergic, glutamatergic and neuropeptide Y systems on hypophagia caused by gastric inhibitory polypeptide (GIP) in broilers. [PDF]

Poult Sci
Gharaie ML, Zendehdel M, Zarei H, Mahdavi K.   +3 more
europepmc   +1 more source

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Characterization of Melanocortin Receptors

Current Protocols in Pharmacology, 2003
AbstractThis unit describes a Scintillation Proximity Assay (SPA) for the measurement of ligand binding to melanocortin receptors (MCRs) using membranes prepared from cell lines stably expressing recombinant MCRs. It provides a facile method for determining the affinity of compounds at MC1R, MC3R, MC4R, or MC5R.
Aaron S, Goetz, Diane M, Ignar
openaire   +2 more sources

Melanocortins and their Receptors and Antagonists

Current Drug Targets, 2003
The melanocortins are a group of small protein hormones derived by post-translational cleavage of the proopiomelanocortin (POMC) gene product. The known melanocortin hormones include alpha-melanocyte stimulating hormone (MSH), beta-MSH, gamma-MSH and adrenocorticotropic hormone (ACTH).
Voisey, J, Carroll, L, van Daal, A
openaire   +3 more sources

Evolution of melanocortin receptors in teleost fish: The melanocortin type 1 receptor

Gene, 2007
The melanocortin type 1 receptor (Mc1r) belongs to a family of G-protein-coupled receptors involved in various physiological processes in vertebrates. Melanocortins, the Mcr natural agonists, are pituitary peptide hormones including adrenocorticotropin and melanocyte-stimulating hormones.
Yvonne, Selz, Ingo, Braasch, Carsten, Hoffmann, Cornelia, Schmidt, Christina, Schultheis, Manfred, Schartl, Jean-Nicolas, Volff   +6 more
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Involvement of melanocortin receptor accessory proteins (MRAPs) in the function of melanocortin receptors

General and Comparative Endocrinology, 2013
The melanocortin system integrates different agonists, competitive or inverse agonists, and receptors. Recent investigations have also discovered a specific system of melanocortin receptor accessory proteins (MRAPs) that are involved in the regulation of the functional expression of these receptors.
Cerdá-Reverter, José Miguel, Agulleiro Gozalbo, Maria Josep, Cortés, Raúl, Sánchez Martínez, Elisa, Guillot, Raúl, Leal, Esther, Fernández-Durán, Begoña, Puchol, Sara, Eley, M.   +8 more
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New ligands for melanocortin receptors

International Journal of Obesity, 2008
Named originally for their effects on peripheral end organs, the melanocortin system controls a diverse set of physiological processes through a series of five G-protein-coupled receptors and several sets of small peptide ligands. The central melanocortin system plays an essential role in homeostatic regulation of body weight, in which two alternative ...
C B, Kaelin, S I, Candille, B, Yu, P, Jackson, D A, Thompson, M A, Nix, J, Binkley, G L, Millhauser, G S, Barsh   +8 more
openaire   +2 more sources