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Melanocortins and Adrenocortical Function
2000Although the existence of a functional relationship between the pituitary gland and the adrenal cortex was revealed by the classic studies of Smith almost seventy years ago (1),the first purified adrenocorticotropin (ACTH) preparation from sheep pituitary was obtained only in 1954 (2), and its structure was determined in the following few years (3). In
Bégeot, Martine, Saez, J.M.
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The Journal of Pharmacology and Experimental Therapeutics, 1995
The melanocortins are peptide products of proopiomelanocortin post-translational processing that, among other functions, are thought to influence cognition. Recently, we isolated genes encoding two human melanocortin receptors, the melanocortin-3 receptor (hMC3R) and the melanocortin-4 receptor (hMC4R), which are expressed primarily in brain.
H, Miwa +4 more
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The melanocortins are peptide products of proopiomelanocortin post-translational processing that, among other functions, are thought to influence cognition. Recently, we isolated genes encoding two human melanocortin receptors, the melanocortin-3 receptor (hMC3R) and the melanocortin-4 receptor (hMC4R), which are expressed primarily in brain.
H, Miwa +4 more
openaire +2 more sources
Permeability of the blood-brain barrier to melanocortins
Peptides, 1995William Banks, A J Kastin
exaly