Results 101 to 110 of about 3,506 (222)

Exploring the impact of Cabotegravir‐Rilpivirine long‐acting on weight gain, body composition and quality of life in adults living with HIV

HIV Medicine, Volume 27, Issue 5, Page 727-739, May 2026.
Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito, Andrea Marongiu, Antonella Cano, Mariangela Puci, Agnese Colpani, Susanna Maria Nuvoli, Maria Grazia Catte, Giulia Moi, Maria Antonietta Deledda, Sergio Uzzau, Giovanni Sotgiu, Franca Deriu, Angela Spanu, Giordano Madeddu   +13 more
wiley   +1 more source

Global consensus on the management of melanin hyperpigmentation disorders

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 760-772, May 2026.
A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron, Seemal R. Desai, Marwa Abdallah, Firas Al‐Niaimi, Ncoza Dlova, Pearl E. Grimes, Jorge Ocampo‐Candiani, Rashmi Sarkar, Leihong Flora Xiang, Helio Amante Miot   +9 more
wiley   +1 more source

Teenage acne and cancer risk in U.S. women: A prospective cohort study [PDF]

, 2015
BACKGROUND: Acne reflects hormone imbalance and is a key component of several systemic diseases. We hypothesized that diagnosis of acne as a teenager might predict subsequent risk of hormone-related cancers.
Eliassen, A. Heather, Fortner, Renée T., Han, Jiali, Hankinson, Susan E., Hunter, David J., Qureshi, Abrar A., Wang, Li-E, Wei, Qingyi, Willett, Walter C., Zhang, Mingfeng   +9 more
core   +1 more source

Germline MC1R status influences somatic mutation burden in melanoma [PDF]

, 2016
The major genetic determinants of cutaneous melanoma risk in the general population are disruptive variants (R alleles) in the melanocortin 1 receptor (MC1R) gene.
A Ozola, A Yates, C Wilks, CM Olsen, D Mitra, DL Duffy, DT Bishop, E Healy, E Hodis, E Pasquali, ED Pleasance, H Ikehata, I Adzhubei, J Cao, JA Newton-Bishop, JC García-Borrón, JE Hauser, JJ Latimer, JR Davies, JS Más, K Cibulskis, K Jagirdar, KA Beaumont, KA Beaumont, L Denat, LB Alexandrov, M Krauthammer, M Krauthammer, MF Berger, P Shriber, P Valverde, PB Cassidy, PC Ng, PF Williams, RA Sturm, S Raimondi, S van Buuren, SA Forbes, SG Jarrett, SG Jarrett, T Dwyer, TH Nasti, V Swope, YW Teh, Z Zhang, ZA Abdel-Malek   +45 more
core   +1 more source

Hypoxia inducible factor-dependent upregulation of Agrp in glomus type I cells of the carotid body

Molecular Metabolism
Agouti-related peptide (AgRP) is a well-established potent orexigenic peptide primarily expressed in hypothalamic neurons. Nevertheless, the expression and functional significance of extrahypothalamic AgRP remain poorly understood.
Luis Leon-Mercado, Ivan Menendez-Montes, Jonathan Tao, Bandy Chen, David P. Olson, C. Mackaaij, C.G.J. Cleypool, Laurent Gautron   +7 more
doaj   +1 more source

Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormone (ACTH)

Frontiers in Neurology, 2013
Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for ...
Amy ePerrin Ross, Aliza eBen-Zacharia, Colleen J Harris, Jennifer eSmrtka   +3 more
doaj   +1 more source

Emerging drug targets for Aβ and tau in Alzheimer's disease: a systematic review [PDF]

, 2015
Currently, treatment for Alzheimer's disease (AD) focuses on the cholinergic hypothesis and provides limited symptomatic effects. Research currently focuses on other factors that are thought to contribute to AD development such as tau proteins and Aβ ...
Agbemenyah, Avila, Barron, Bitner, Camboni, Chen, Cioanca, Corona, DeMattos, Durairajan, Farr, Geekiyanage, Giuliani, Hernandez, Hoppe, Inestrosa, Kang, Kang, Kashiwaya, Li, Lo, Morris, Niedowicz, Nikkel, O'Hare, Perez-Gonzalez, Qin, Qosa, Ramalho, Shytle, Sierksma, Sung, Vepsäläinen, Wang, Xue, Yang   +35 more
core   +1 more source

Defining Acquired Hypothalamic Obesity: An Expert Call for Unified Diagnosis and Therapeutic Action

Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4437-4441, June 2026.
Hanneke M. van Santen, Ashley H. Shoemaker, Mehul T. Dattani, Christian L. Roth, Mohamad Maghnie, Kevin C. J. Yuen, Christine Poitou, Hermann L. Müller   +7 more
wiley   +1 more source

The Melanocortin System: A Promising Target for the Development of New Antidepressant Drugs. [PDF]

Int J Mol Sci, 2023
Markov DD, Dolotov OV, Grivennikov IA.
europepmc   +1 more source

Effects of monosodium-L-glutamate administration on serum levels of reproductive hormones and cholesterol, epididymal sperm reserves and testicular histomorphology of male albino rats [PDF]

, 2015
This study investigated the effects of administration of monosodium L-glutamate (MSG) on serum gonadotrophin-releasing hormone (GnRH), luteinising hormone (LH), testosterone and total cholesterol (TC), cauda epididymal sperm reserves (CESR) and ...
Ahluwalia P., Allain C. C., Allen D. H., Amman R. P., Bazzano G., Bhattacharya T., Bodnár I., Chidozie Okoye, Chukwuka Uchendu, David Ogwu, Dieguez C., Ebling F. J., Edmund Mbegbu, Ekins R. P., Fernandes G. S., Gallagher R., Gong S. L., Hu J., Igwebuike U. M., Inyang B., Ismail N. H., Izuchukwu Ochiogu, John Ihedioha, McLachlan R. I., Meraiyebu A., Mohamed I. K., Nayanatara A., Nemeroff C. B., Norris D. O., Nosseir N. S., Olney J. W., Pakarainen T., Palkovits M., Pizzi W. J., Reynolds W. A., Rhodes J., Sahelian R., Stocco D. M., Tafelski T. J., Tordoff M. G., Walker W. H., Wang R., Yang W. H.   +42 more
core   +1 more source