Results 111 to 120 of about 185,946 (280)

Development of a genetically encoded melanocortin sensor for high sensitivity in vivo imaging

Molecular Metabolism
Objective: The central melanocortin system, composed of peptides derived from pro-opiomelanocortin (POMC) such as the melanocyte-stimulating hormones (α-, β-, γ-MSH) and melanocortin 4 receptors (MC4R), along with the agouti-related protein (AgRP), plays
Yoon Namkung, Tal Slutzki, Joao Pedroso, Xiaohong Liu, Paul V. Sabatini, Maia V. Kokoeva, Stéphane A. Laporte   +6 more
doaj   +1 more source

Subclinical hypothyroidism in obese children [PDF]

, 2013
Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) associated with normal levels of free thyroxine. In obese persons prevalence of SH is significantly higher than in general population.
Aleksandra Januszek-Trzciąkowska, Ewa Małecka-Tendera   +1 more
core   +1 more source

Ribosomal S6 kinase 2-forkhead box protein O4 signaling pathway plays an essential role in melanogenesis

Scientific Reports
Although previous studies have examined the signaling pathway involved in melanogenesis through which ultraviolet (UV) or α-melanocyte-stimulating hormones (α-MSH) stimuli act as key inducers to produce melanin at the stratum basal layer of the epidermis,
Dohyun Jeung, Ga-Eun Lee, Weidong Chen, Jiin Byun, Soo-Bin Nam, You-Min Park, Hye Suk Lee, Han Chang Kang, Joo Young Lee, Kwang Dong Kim, Young-Soo Hong, Cheol-Jung Lee, Dae Joon Kim, Yong-Yeon Cho   +13 more
doaj   +1 more source

Fibronectin-Containing Extracellular Vesicles Protect Melanocytes against Ultraviolet Radiation-Induced Cytotoxicity. [PDF]

Skin melanocytes are activated by exposure to UV radiation to secrete melanin-containing melanosomes to protect the skin from UV-induced damage. Despite the continuous renewal of the epidermis, the turnover rate of melanocytes is very slow, and they ...
Bhin, J, Bin, BH, Cho, EG, Choi, EJ, Gho, YS, Kim, DK, Kim, NH, Kim, ST, Lee, AY, Lee, TR   +9 more
core   +1 more source

Peptidylglycine alpha-amidating monooxygenase is important in mice for beta-cell cilia formation and insulin secretion but promotes diabetes risk through beta-cell independent mechanisms

Molecular Metabolism
Objectives: Carriers of PAM (peptidylglycine alpha-amidating monooxygenase) coding variant alleles have reduced insulinogenic index, higher risk of developing type 2 diabetes (T2D), and islets from heterozygous carriers of the PAM p.Asp563Gly variant ...
Yi-Chun Chen, Nils E. Bäck, Jenicia Zhen, Lena Xiong, Mitsuhiro Komba, Anna L. Gloyn, Patrick E. MacDonald, Richard E. Mains, Betty A. Eipper, C. Bruce Verchere   +9 more
doaj   +1 more source

The experimental generation of antibodies to alpha-melanocyte stimulating hormone and adrenocorticotropic hormone. [PDF]

, 1965
Joseph McGuire, R. McGill, Susan E. Leeman, Theodore L. Goodfriend   +3 more
openalex   +1 more source

The effect of an exteroceptive stimulus on the concentration of melanocyte‐stimulating hormone in the pituitary of lactating rats [PDF]

, 1968
R. P. Deis, R. Orías
openalex   +1 more source

The effect of active immunization against adrenocorticotropic hormone on cortisol, beta-endorphin, vocalization, and growth in pigs [PDF]

, 2005
Because the poor growth performance of intensively housed pigs is associated with increased circulating glucocorticoid concentrations, we investigated the effects of glucocorticoid suppression by inducing a humoral immune response to ACTH on ...
Bryden, W. L., Collins, D. C., Downing, J. A., Giles, L. R., Lee, C., Wynn, P. C.   +5 more
core  

Toksikologija bioregulatora kao potencijalnih bioloških agensa [PDF]

, 2005
Bioregulators or modulators are biochemical compounds such as peptides, that occur naturally in organisms. Advances in biotechnology create the potential for the misuse of peptide bioregulators in offensive biological weapons programmes.
Slavko Bokan
core   +1 more source

On the adrenal subcellular distibution of 3H-ACTH [PDF]

, 1968
Margoulies, M., Müller, O. A., Scriba, Peter Christian   +2 more
core   +1 more source