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Neuroendocrine and Molecular Interactions in Eating Disorders [PDF]
There are three basic pillars for the development of eating disorders: genetic predisposition, neuro-endocrine-molecular changes in the brain and metabolic response to it.
Selma Bozkurt Zincir
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Cystic fibrosis (CF), which is the most common inherited genetically determined disease caused by a mutation in the gene for the CF transmembrane conductance regulator protein. Pulmonary failure is the leading cause of death in this population, while the
Sabina Galiniak+3 more
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Differential Signaling Profiles of MC4R Mutations with Three Different Ligands [PDF]
The melanocortin 4 receptor (MC4R) is a key player in hypothalamic weight regulation and energy expenditure as part of the leptin-melanocortin pathway. Mutations in this G protein coupled receptor (GPCR) are the most common cause for monogenetic obesity,
Annibale, Paolo+8 more
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Evaluation of the Hypothalamus-Hypophysis-Adrenal Axis in Male Rats Programmed by Gestational Protein Restriction. [PDF]
ABSTRACT Diet manipulations during the gestation of animal models, in this case, the lipoprotein diet, mimic the alterations related to low birth weight, providing studies of the mechanisms involved in chronic disease development in later life. Our research group identified in adult male rats submitted to gestational protein restriction, increased ...
Mariano VS, Gontijo JAR, Boer PA.
europepmc +2 more sources
Melanocortin-3 receptor (MC3R) is a regulator of energy homeostasis, and interaction of MC3R and melanocortin-2 receptor accessory protein 2 (MRAP2) plays a critical role in MC3R signaling of mammals.
Ren-Lei Ji+6 more
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Endocrinologic Control of Men's Sexual Desire and Arousal/Erection [PDF]
Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aversa, Antonio+4 more
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Purpose: The active melanocytes in the skin were affected by hormones and ultraviolet (UV) irradiation. Licorice zinc has a whitening effect, which may have a prominent potential in the treatment of pigmented skin disease.
Jing-yan Wang+6 more
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Keratinocytes regulate the function of melanocytes
Mammalian keratinocytes compose the bulk of the epithelium, undergo keratinization, and form the dead superficial layer of the skin. These superficial keratinized cells are continuously replaced by cells derived from mitotic cells in the lowest layer of ...
Tomohisa Hirobe
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Transgenerational Social Stress, Immune Factors, Hormones, and Social Behavior
A social signal transduction theory of depression has been proposed that states that exposure to social adversity alters the immune response and these changes mediate symptoms of depression such as anhedonia and impairments in social behavior.
Christopher Anthony Murgatroyd+5 more
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