Results 21 to 30 of about 412,755 (166)
α-Melanocyte-stimulating hormone modulates nitric oxide production in melanocytes
, 2000 We have previously observed that melanocytes produce nitric oxide in response to ultraviolet radiation and lipopolysaccharide and in this study have examined how these responses are affected by α-melanocyte-stimulating hormone. Nitric oxide production by
Graham AM +7 more
core +5 more sources
Melanocortin Regulation of Inflammation
Frontiers in Endocrinology, 2019 Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin receptors), are components of an ancient modulatory system.
Wei Wang +3 more
doaj +1 more source
Selected hormonal and neurotransmitter mechanisms regulating feed intake in sheep
Animal, 2010 Appetite control is a major issue in normal growth and in suboptimal growth performance settings. A number of hormones, in particular leptin, activate or inhibit orexigenic or anorexigenic neurotransmitters within the arcuate nucleus of the hypothalamus,
J.L. Sartin +3 more
doaj +1 more source
The multiplicity of post-translational modifications in pro-opiomelanocortin-derived peptides
Frontiers in Endocrinology, 2013 The precursor protein, pro-opiomelanocortin (POMC) undergoes extensive post-translational processing in a tissue-specific manner to yield various biologically active peptides involved in diverse cellular functions.
Akikazu eYasuda +2 more
doaj +1 more source
Frontiers in Endocrinology, 2021 Proopiomelanocortin (POMC) deficiency is an extremely rare inherited autosomal recessive disorder characterized by severe obesity, adrenal insufficiency, skin hypopigmentation, and red hair. It is caused by pathogenic variants in the POMC gene that codes
Nadan Gregoric +18 more
doaj +1 more source
Veterinární Medicína, 2015 The hypothalamic-pituitary-adrenal axis (HPA) is a complex system regulated by multiple factors. Sexual dimorphism of this axis has been described in different species under physiological conditions and it has been proposed that sexual hormones could ...
M.F. Gallelli +6 more
doaj +1 more source
α-MSH analogue attenuates blood pressure elevation in DOCA-salt hypertensive mice. [PDF]
PLoS ONE, 2013 Melanocyte-stimulating hormones, α-, β- and γ-MSH, regulate important physiological functions including energy homeostasis, inflammation and sodium metabolism.
Petteri Rinne +4 more
doaj +1 more source
Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice
Molecular Metabolism, 2019 Objective: Life-threatening hypoglycemia is a major limiting factor in the management of diabetes. While it is known that counterregulatory responses to hypoglycemia are impaired in diabetes, molecular mechanisms underlying the reduced responses remain ...
Benjamin P. Tooke +8 more
doaj +1 more source
D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway. [PDF]
PLoS ONE, 2016 Sepsis induces anorexia and muscle wasting secondary to an increase in muscle proteolysis. Melanocyte stimulating hormones (MSH) is a family of peptides that have potent anti-inflammatory effects.
Ana Belén Gómez-SanMiguel +3 more
doaj +1 more source
Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormone (ACTH)
Frontiers in Neurology, 2013 Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for ...
Amy ePerrin Ross +3 more
doaj +1 more source