Results 21 to 30 of about 12,621 (225)

Insight into Potential Interactions of Thyroid Hormones, Sex Hormones and Their Stimulating Hormones in the Development of Non-Alcoholic Fatty Liver Disease

, 2022
Non-Alcoholic Fatty Liver Disease (NAFLD) is a common manifestation of metabolic syndrome. In addition to lifestyle, endocrine hormones play a role in the dysregulation of hepatic metabolism.
Fröhlich, Eleonore, Wahl, Richard, Eleonore Fröhlich, Richard Wahl   +3 more
core   +1 more source

Two Cases With an Early Presented Proopiomelanocortin Deficiency—A Long-Term Follow-Up and Systematic Literature Review

Frontiers in Endocrinology, 2021
Proopiomelanocortin (POMC) deficiency is an extremely rare inherited autosomal recessive disorder characterized by severe obesity, adrenal insufficiency, skin hypopigmentation, and red hair. It is caused by pathogenic variants in the POMC gene that codes
Nadan Gregoric, Nadan Gregoric, Urh Groselj, Urh Groselj, Natasa Bratina, Natasa Bratina, Marusa Debeljak, Marusa Debeljak, Mojca Zerjav Tansek, Mojca Zerjav Tansek, Jasna Suput Omladic, Jasna Suput Omladic, Jernej Kovac, Tadej Battelino, Tadej Battelino, Primoz Kotnik, Primoz Kotnik, Magdalena Avbelj Stefanija, Magdalena Avbelj Stefanija   +18 more
doaj   +1 more source

Plasma ACTH, α-MSH and cortisol variations in the dog during the oestrous cycle in different photoperiods

Veterinární Medicína, 2015
The hypothalamic-pituitary-adrenal axis (HPA) is a complex system regulated by multiple factors. Sexual dimorphism of this axis has been described in different species under physiological conditions and it has been proposed that sexual hormones could ...
M.F. Gallelli, N. Monachesi, D.D. Miceli, M.F. Cabrera Blatter, N.V. Gomez, A. Meikle, V.A. Castillo   +6 more
doaj   +1 more source

α-MSH analogue attenuates blood pressure elevation in DOCA-salt hypertensive mice. [PDF]

PLoS ONE, 2013
Melanocyte-stimulating hormones, α-, β- and γ-MSH, regulate important physiological functions including energy homeostasis, inflammation and sodium metabolism.
Petteri Rinne, Anna-Maija Penttinen, Wendy Nordlund, Markku Ahotupa, Eriika Savontaus   +4 more
doaj   +1 more source

Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]

, 2012
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M., Ana Monteiro, Abel Margaret, Margaret Abel, Peter J. O’Shaughnessy (171628), O’Shaughnessy Peter J., Monteiro, A., O'Shaughnessy, P.J., Ana Monteiro (171632), Peter J O'Shaughnessy, Margaret Abel (171636), Monteiro Ana   +11 more
core   +1 more source

Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice

Molecular Metabolism, 2019
Objective: Life-threatening hypoglycemia is a major limiting factor in the management of diabetes. While it is known that counterregulatory responses to hypoglycemia are impaired in diabetes, molecular mechanisms underlying the reduced responses remain ...
Benjamin P. Tooke, Hui Yu, Jessica M. Adams, Graham L. Jones, Talisha Sutton-Kennedy, Lakshmi Mundada, Nathan R. Qi, Malcolm J. Low, Kavaljit H. Chhabra   +8 more
doaj   +1 more source

D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway. [PDF]

PLoS ONE, 2016
Sepsis induces anorexia and muscle wasting secondary to an increase in muscle proteolysis. Melanocyte stimulating hormones (MSH) is a family of peptides that have potent anti-inflammatory effects.
Ana Belén Gómez-SanMiguel, María Ángeles Villanúa, Ana Isabel Martín, Asunción López-Calderón   +3 more
doaj   +1 more source

Multiple sclerosis, relapses, and the mechanism of action of adrenocorticotropic hormone (ACTH)

Frontiers in Neurology, 2013
Relapses in multiple sclerosis (MS) are disruptive and frequently disabling for patients, and their treatment is often a challenge to clinicians. Despite progress in the understanding of the pathophysiology of MS and development of new treatments for ...
Amy ePerrin Ross, Aliza eBen-Zacharia, Colleen J Harris, Jennifer eSmrtka   +3 more
doaj   +1 more source

The role of proopiomelanocortin (POMC) neurones in feeding behaviour

Nutrition & Metabolism, 2007
The precursor protein, proopiomelanocortin (POMC), produces many biologically active peptides via a series of enzymatic steps in a tissue-specific manner, yielding the melanocyte-stimulating hormones (MSHs), corticotrophin (ACTH) and β-endorphin.
Millington George WM
doaj   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source