Results 101 to 110 of about 78,152 (310)

Paraneoplastic Florid Oral Papillomatosis and Malignant Acanthosis Nigricans Associated With HPV‐Related Squamous Cell Carcinoma of Unknown Primary

JEADV Clinical Practice, EarlyView.
ABSTRACT We present the case of a 76‐year‐old man with paraneoplastic florid oral papillomatosis (FOP) and malignant acanthosis nigricans (MAN) associated with an HPV‐16‐positive keratinizing squamous cell carcinoma of unknown primary. The patient initially presented with a painless left cervical mass and was diagnosed through cytology and PET‐CT ...
Jose Ángel Amat‐Sanchez, Ander Paulo Mayor‐Ibarguren, María José Beato‐Merino, Blanca Martínez‐Cabrera, Beatriz Castelo‐Fernández, Francisco Vergara‐Barria, Pedro Herranz‐Pinto   +6 more
wiley   +1 more source

Reversal of Canities in a Patient With Frontal Fibrosing Alopecia

JEADV Clinical Practice, EarlyView.
ABSTRACT Frontal fibrosing alopecia (FFA) is a primary lymphocytic cicatricial alopecia, most commonly affecting postmenopausal women, characterized by progressive frontotemporal hairline recession and eyebrow loss. Hair repigmentation (canities reversal) is an extremely rare event, especially in older individuals with long‐standing white hair.
Nicolò Rivetti
wiley   +1 more source

Identification of Gene Variants Associated with Melanocyte Stem Cell Differentiation in Mice Predisposed for Hair Graying

G3: Genes, Genomes, Genetics, 2019
Age-related hair graying is caused by malfunction in the regenerative potential of the adult pigmentation system. The retention of hair color over the life of an organism is dependent on the ability of the melanocyte stem cells and their progeny to ...
Allison C. Fialkowski, Denise J. Levy, Dawn E. Watkins-Chow, Joseph W. Palmer, Roshan Darji, Hemant K. Tiwari, William J. Pavan, Melissa L. Harris   +7 more
doaj   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K, Saric-Bosanac, Suzana, Shi, Vivian Y, Sivamani, Raja K   +3 more
core  

Effect of Uveal Melanocytes on Choroidal Morphology in Rhesus Macaques and Humans on Enhanced-Depth Imaging Optical Coherence Tomography [PDF]

, 2016
Glenn Yiu, Vivian S. Vuong, Sharon L. Oltjen, David Cunefare, Sina Farsiu, Laura M. Garzel, Jeffrey A. Roberts, Sara M. Thomasy   +7 more
openalex   +1 more source

Reduced Visibility of Pigment Network Under Sub‐UV Reflectance Dermatoscopy Compared to Polarised Dermatoscopy: A Novel Diagnostic Clue to Differentiate Melanomas From Nevi

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Melanoma accounts for more than 75% of skin cancer‐related mortality. Dermatoscopy is an evidence‐based technique for earlier detection, yet differentiating melanocytic lesions remains challenging. Sub‐UV reflectance dermatoscopy (sUVRD) uses purple light (405 nm) to visualise chromophore distribution in the skin.
L. Dupont, P. Pietkiewicz, J. Anriot, P. Greco, A. Petiot‐Walch, C. Coste, E. Aurambout, S. Darnis, M. Amini‐Adle, L. Thomas   +9 more
wiley   +1 more source

Generation of human melanocytes from induced pluripotent stem cells.

PLoS ONE, 2011
Epidermal melanocytes play an important role in protecting the skin from UV rays, and their functional impairment results in pigment disorders. Additionally, melanomas are considered to arise from mutations that accumulate in melanocyte stem cells.
Shigeki Ohta, Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Reiko Kuwahara, Manabu Ohyama, Masayuki Amagai, Yumi Matsuzaki, Shinya Yamanaka, Hideyuki Okano, Yutaka Kawakami   +10 more
doaj   +1 more source

Systemic Absorption and Pharmacokinetics of Five Novel Topical Dermatologic Agents: A Review

JEADV Clinical Practice, EarlyView.
ABSTRACT In recent years, innovative topical medications with novel mechanisms of action have emerged to treat common dermatologic conditions such as acne, atopic dermatitis, vitiligo, and actinic keratoses. These molecularly targeted therapies offer improved safety and tolerability compared to traditional options like corticosteroids.
Mary Dyson, Kara Hurley, Hannah Chaudhury, Lara Shehadeh, Cameron West   +4 more
wiley   +1 more source

Prospective Evaluation of a Fractional 675‐nm Nonablative Laser for Atrophic Acne Scars in Fitzpatrick Skin Types III–IV

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Energy‐based treatments for atrophic acne scars (AAS) in darker skin phototypes must balance efficacy with pigmentary safety. While the nonablative 675‐nm laser has shown promise with minimal risk of adverse effects, prospective data in Asian populations remain limited.
Pinthisa Nisagornsen, Panwadee Thongjaroensirikul, Yanin Nokdhes, Woramate Bhorntarakcharoen, Sariya Sittiwanaruk, Jayne Bernadeth Li, Woraphong Manuskiatti   +6 more
wiley   +1 more source

Interventions to Prevent Postinflammatory Hyperpigmentation After Laser and Energy‐Based Device Treatments: A Systematic Review and Network Meta‐Analysis

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Background Postinflammatory hyperpigmentation (PIH) is the most common adverse effect following laser treatments, yet the relative efficacy of proposed prophylactic measures remains uncertain. Objectives To compare the effectiveness of available interventions for preventing laser‐induced PIH in randomized controlled trials (RCTs).
Supisara Wongdama, Sasitorn Yenyuwadee, Jayne Bernadeth Li, Surasak Saokaew, Sukrit Kanchanasurakit, Woraphong Manuskiatti   +5 more
wiley   +1 more source