Results 81 to 90 of about 53,753 (240)

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Identifying the niche controlling melanocyte differentiation

, 2017
Melanocytes present in hair follicles are responsible for their pigmentation. Melanocyte differentiation and hair pigmentation depend on the stem cell factor (SCF)/c-Kit signaling pathway, but thenichetha tregulates melanocyte differentiation is not well
Cédric Blanpain, Blanpain, Cédric, Zocco, Manuel, Manuel Zocco   +3 more
core   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

A Case of Polypoid Intraoral Nevus in Buccal Mucosa: a Case Report

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2020
BACKGROUND AND OBJECTIVE: Mouth discoloration can be of internal or external origin. Melanotic nevus are the result of benign proliferation of melanocytes, the intraoral type of which is not as common as melanotic skin moles.
S Baghery moghadam, N Mortazavi, AR Ahmadinia, F Mirzaei   +3 more
doaj  

UVB represses melanocyte cell migration and acts through β-catenin

, 2017
The exposure of skin to ultraviolet (UV) radiation can have both beneficial and deleterious effects: it can lead, for instance, to increased pigmentation and vitamin D synthesis but also to inflammation and skin cancer.
Larue, Lionel, Bertrand, Juliette U., Sage, Evelyne, Lionel Larue, Bertrand, Juilette U., Irina Berlin, Petit, Valérie, David C. Whiteman, Valérie Petit, Marie Pouteaux, Hacker, Elke, Berlin, Irina, Juliette U. Bertrand, Elke Hacker, Evelyne Sage, Hayward, Nicholas K., Whiteman, David C., Nicholas K. Hayward, Pouteaux, Marie   +18 more
core   +1 more source

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini, Mallorie P. Jenne, Michael L. Piacentino   +2 more
wiley   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

Developmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister, Keisuke Sugiwaka, Tetsuaki Kimura, Rieko Tanaka, Makoto Goda, Hikaru Kobayashi, Chikako Inoue, Kawilarang W. A. Masengi, Kazunori Yamahira, Kiyoshi Naruse, Satoshi Ansai, Robert N. Kelsh, Masahiko Hibi, Hisashi Hashimoto   +13 more
wiley   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

JSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras, Andreas Thrasyvoulou, Evanthia Tsilimpokou   +2 more
wiley   +1 more source

Melanoma mutations modify melanocyte dynamics in co-culture with keratinocytes or fibroblasts

, 2019
Melanocytic cell interactions are integral to skin homeostasis, and affect the outcome of multiple diseases, including cutaneous pigmentation disorders and melanoma.
Škalamera, Dubravka, Lanagan, C, Gabrielli, Brian, Ehmann, Anna, Ainger, Stephen A., Gabrielli, B, Škalamera, D, Ehmann, A, Stevenson, Alexander J., Sturm, Richard A., Lanagan, Catherine, Stevenson, AJ, Sturm, RA, Ainger, SA   +13 more
core   +1 more source

LC‐OCT Features in Vitiligo: A Preliminary Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Vitiligo is a chronic depigmenting disorder characterized by the selective loss of melanocytes, leading to the progressive development of hypopigmented macules and patches. Line‐field confocal optical coherence tomography (LC‐OCT) is a novel imaging technique that combines the advantages of optical coherence tomography (OCT) and ...
Gerardo Palmisano, Daniele Omar Traini, Lorenzo Maria Pinto, Alessandra D'Amore, Mariano Suppa, Alessandro Di Stefani, Ketty Peris   +6 more
wiley   +1 more source