Results 101 to 110 of about 53,753 (240)
The FOXQ1/SSBP2 Regulatory Axis Drives Malignant Progression of Melanoma
Molecular Carcinogenesis, EarlyView.ABSTRACT Melanoma is a highly aggressive skin cancer with poor prognosis, often linked to excessive UV exposure. Despite advancements in immunotherapy and targeted treatments, melanoma's invasiveness and metastatic potential remain significant challenges.
Xiaoyu Zhang +4 more
wiley +1 more source
Vitiligo and the melanocyte reservoir
Indian Journal of Dermatology, 2009 Repigmentation of vitiligo depends on available melanocytes from three possible sources: from the hair follicle unit which is the main provider of pigment cells, from the border of vitiligo lesions, and from unaffected melanocytes within depigmented ...
Falabella Rafael
doaj
Molecular genetics and mechanisms of pigmentation and melanoma [PDF]
, 2010 Ever since man domesticated the first wild animals several thousand years ago, many species have been living in close relationship with humans, being objects for our requests and wishes about any kind of phenotypic traits.
Sundström, Elisabeth
core
, 2018 Dalia Bassiouny, Samia Esmat Department of Dermatology, Kasr El-Ainy Teaching Hospital, Faculty of Medicine, Cairo University, Cairo, Egypt Abstract: Autologous non-cultured melanocyte–keratinocyte transplantation procedure (MKTP) is one of the ...
Bassiouny D, Esmat S
core
Melanocyte uniformity measurements.
, 2012 As quantitative measurements of the three different mechanisms’ ability to distribute melanocytes evenly, we counted the number of melanocytes with three or more melanocyte neighbors (top), and the relative standard deviation of the distance from all ...
Timothy J. Lavelle (152636) +3 more
core +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
Medicinal Research Reviews, EarlyView.ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Zoom-in Dermoscopy for Facial Tumors
DiagnosticsBackground/Objectives: Facial lesions, including lentigo maligna and lentigo maligna melanoma (LM/LMM), both malignant, present significant diagnostic challenges due to their clinical similarity to benign conditions.
Martina D’Onghia +9 more
doaj +1 more source
The Journal of Pathology, EarlyView.Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti +21 more
wiley +1 more source
Local sympathetic nerve depletion does not alter vitiligo progression in a mouse model
Frontiers in MedicineVitiligo, an autoimmune skin disorder characterized by melanocyte loss, has long been associated with sympathetic nervous system activity. Clinical observations have suggested links between psychological stress, sympathetic activation, and vitiligo ...
Zhichao Hu +5 more
doaj +1 more source