ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Electron microscopy in Cogan–Reese syndrome
Geeta Behera +3 more
doaj +1 more source
Prostaglandin‐E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis‐independent manner [PDF]
Karl Gledhill +7 more
openalex +1 more source
Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley +1 more source
Prospects for non-immunological molecular therapeutics in melanoma [PDF]
In 2006 there were 60,000 new cases of cutaneous melanoma in the European Union and 13,000 deaths (www.europeancancerleagues.org). Currently available systemic treatment options for metastatic melanoma, including both cytotoxic and immunologic therapies,
Crown, John +4 more
core
Health‐Related Quality of Life and Psychological Burden of Patients With Vitiligo in Japan
ABSTRACT Vitiligo is a disorder characterized by depigmentation of the skin and is known to impact patients' health‐related quality of life (HRQoL). In Japan, HRQoL studies on vitiligo remain limited in size and scope, and factors contributing to impaired HRQoL, as well as the psychological burden, have not been adequately evaluated.
Naoki Oiso +5 more
wiley +1 more source
Pathogenesis of Chemical Leukoderma and Chemical‐Induced Vitiligo
ABSTRACT Leukoderma/vitiligo is a serious pigmentary disorder that notably impairs the patient's quality of life. In particular, chemical leukoderma (CL)/vitiligo refers to acquired depigmentation of the skin induced by exposure to certain chemicals. In this review, the term “CL” is defined as the temporary, localized loss of pigmentation at the site ...
Yasutaka Kuroda +2 more
wiley +1 more source
Prostaglandin E2 regulates melanocyte dendrite formation through activation of PKCζ
Glynis Scott +4 more
openalex +1 more source
Relevance of the C‐terminal Arg‐Phe sequence in γ2‐melanocyte‐stimulating hormone (γ2‐MSH) for inducing cardiovascular effects in conscious rats [PDF]
Marjoleen Nijsen +4 more
openalex +1 more source
Beyond Pathology: α‐Synuclein Homeostasis and Three Principles to Guide Research
Movement Disorders Clinical Practice, EarlyView.
Alberto J. Espay, Andrew J. Lees
wiley +1 more source

