Results 131 to 140 of about 92,933 (386)

The initiator methionine tRNA drives cell migration and invasion leading to increased metastatic potential in melanoma [PDF]

, 2016
The cell's repertoire of transfer RNAs (tRNAs) has been linked to cancer. Recently, levels of the initiator methionine tRNA (tRNAiMet) in stromal fibroblasts have been shown to influence extracellular matrix (ECM) secretion to drive tumour growth and ...
Birch, Joanna, Blyth, Karen, Campbell, Andrew D., Campbell, Kirsteen, Clarke, Cassie, Kalna, Gabriela, Liko, Dritan, Mitchell, Louise, Neilson, Matthew, Norman, Jim C., Sansom, Owen J., Strathdee, Douglas   +11 more
core   +3 more sources

Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Limited information is available on the clinicopathologic features and management of pediatric CRTC1::TRIM11 (CTRTs) and MED15::ATF1‐rearranged tumors (MARTs). In this series of pediatric CTRTs (n = 5) and MARTs (n = 2), all tumors exhibited spitzoid morphology and expressed melanocytic markers.
Michael R. Sargen, Madeline H. Fitzhugh, Jennifer S. Ko, Allison G. Close, Sara C. Horton, Faizan Malik, Larissa V. Furtado, Armita Bahrami, Brittani K. N. Seynnaeve, Alberto S. Pappo, Vincent Liu, Kevin Cheung, Svetlana D. Pack, Liqiang Xi, Mark Raffeld, Ina Lee, Jeffrey Gagan, Kenneth Aldape, Frederic G. Barr, Stephen M. Hewitt, Christina K. Ferrone, Anna Hayden, Jessica N. Hatton, Alisa M. Goldstein, Ruth M. Pfeiffer, Brigitte Widemann, Mary Frances Wedekind Malone, Andrea M. Gross, Rosandra Kaplan, Marielle E. Yohe, Kristen G. Berrebi   +30 more
wiley   +1 more source

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

Small, EarlyView.
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri, Marc Blanch‐Asensio, Ketaki Deshpande, Jonas Baumann, Carole Baumann, Rolf Müller, Sara Trujillo, Shrikrishnan Sankaran   +7 more
wiley   +1 more source

A call to integrate non‐visual functions of pigments and their interactions with visual functions to understand global change impacts on visual systems

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Animal coloration serves a variety of visually related functions in nature (e.g. mate choice, aposematism and camouflage) but the pigments in integumentary tissues such as skin, scales and feathers may also serve functions unrelated to the visual environment (e.g ...
Beth A. Reinke, Julian D. Avery, Jessica Hua   +2 more
wiley   +1 more source

Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy
Vitiligo is a dermatological condition affecting 1% of the global population, characterized by the loss of skin pigmentation. It appears in two main forms: nonsegmental (symmetrical depigmentation) and segmental (localized depigmentation).
Artur Kovenskiy, Nurlubek Katkenov, Zhussipbek Mukatayev, Almagul Kushugulova   +3 more
doaj   +1 more source

A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo.

Endocrinology, 1998
Agouti-related protein (Agrp) is present in rat and human hypothalamus and is structurally related to agouti protein. Overexpression of either of these proteins results in obesity.
M. Rossi, M. S. Kim, D. Morgan, C. Small, C. Edwards, D. Sunter, S. Abusnana, A. Goldstone, S. H. Russell, S. Stanley, David M. Smith, K. Yagaloff, M. Ghatei, S. Bloom   +13 more
semanticscholar   +1 more source

PENGARUH PEMBERIAN SALEP KUNYIT (CURCUMA DOMESTICA)UNTUK MENGURANGI STRIAE GRAVIDARUM : Studi Ibu Hamil Trimester II pada Bidan Praktik Mandiri Wilayah Kerja UPTD Puskesmas Bukit Hindu Kota Palangka Raya [PDF]

, 2016
Latar Belakang : Striae Gravidarum (SG) adalah garis yang terlihat pada kulit perut wanita hamil akibat peregangan kulit sejalan dengan membesarnya rahim dan dinding perut. SG dapat menyebabkan rasa gatal, panas pada guratan dan sekitarnya.
ARIYANTI, Ida, BINGAN, Eline Charla Sabatina, HADISAPUTRO, Soeharyo   +2 more
core  

Strong Signatures of Selection on Candidate Genes Underlying Core Speciation Mechanisms in Desert Tortoises

Molecular Ecology Resources, EarlyView.
ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty, Raúl Araya‐Donoso, Avery Paulsen, Avery Williams, Dale F. DeNardo, Kenro Kusumi, Greer A. Dolby   +6 more
wiley   +1 more source

Studies on pituitary polypeptide hormones. 1. The structure of β-melanocyte-stimulating hormone from pig pituitary glands [PDF]

, 1959
J. Ieuan Harris, P. Roos
openalex   +1 more source

Alpha-Melanocyte–Stimulating Hormone Suppresses Oxidative Stress through a p53-Mediated Signaling Pathway in Human Melanocytes

Molecular Cancer Research, 2012
Epidermal melanocytes are skin cells specialized in melanin production. Activation of the melanocortin 1 receptor (MC1R) on melanocytes by α-melanocyte–stimulating hormone (α-MSH) induces synthesis of the brown/black pigment eumelanin that confers ...
A. L. Kadekaro, Juping Chen, Jennifer Yang, Shun-cun Chen, J. Jameson, V. Swope, T. Cheng, M. Kadakia, Z. Abdel‐Malek   +8 more
semanticscholar   +1 more source