Results 141 to 150 of about 69,018 (287)

Occupational Sun Exposure and Melanoma Development: A Review of the Evidence

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Cutaneous melanomas arise through a number of causal pathways, all of which involve exposure to sunshine or artificial ultraviolet (UV) radiation to some extent. Their initiation also depends on host factors that determine susceptibility to melanoma, and whether the UV exposure is intermittent or chronic.
David C. Whiteman   +2 more
wiley   +1 more source

Low Sunscreen Awareness and Misconceptions in Skin of Colour With Acne‐Related Post‐Inflammatory Hyperpigmentation: A Cross‐Sectional Study Highlighting the Need for Targeted Education

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) is a frequent sequela of acne in patients with skin of colour (SOC). While sunscreen is widely recommended for PIH prevention, little is known about real‐world sunscreen practices in this group. This study aimed to evaluate sunscreen use, barriers and factors influencing adherence
Xiaozhun Hang, Davin Sui Lim, Lisa Byrom
wiley   +1 more source

Demographic Analysis of the Sun Protective Behaviours and Skin Cancer Risk of Victorian Farmers

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background Farmers have an elevated risk of melanoma and non‐melanoma skin cancer due to their occupational exposure to high levels of ultraviolet radiation. The sun protective behaviours of farmers are poorly understood, limiting targeted interventions to this at‐risk population.
Eloise Violet Kwan   +6 more
wiley   +1 more source

Age distribution and characteristics of choroidal nevi in 35 559 individuals: A nationwide study using optometry fundus photography

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To examine the age distribution and characteristics of choroidal nevi in a large nationwide sample. Methods We included all individuals who underwent fundus photography in a nationwide chain of optometry stores during a 5‐week period in 2023.
Carsten Faber   +3 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber   +8 more
wiley   +1 more source

JI‐CJ002 and Dabrafenib Combination Enhances Antitumor Activity in Melanoma Associated With the Downregulation of B7‐H3

open access: yesCancer Science, EarlyView.
Schematic pathway diagram illustrating the effects of JI‐CJ002 and dabrafenib on melanoma progression. The combination of JI‐CJ002 and dabrafenib is associated with reduced B7‐H3 expression and modulation of signaling pathways implicated in melanoma progression, including JAK2/STAT3, PI3K/AKT/mTOR, and Rb/E2F1.
Sang‐Eun Lee   +4 more
wiley   +1 more source

Localized vitiligo occurring in an old biopsy scar: A case report

open access: yesJAAD Case Reports, 2020
Kevin Rychik, BS   +2 more
doaj   +1 more source

Cortical‐Hypothalamic Assembloids Uncover the Cortical Regulation of Hypothalamic Responses to Fatty Acid

open access: yesCell Proliferation, EarlyView.
By assembling cortical‐hypothalamic circuits, we show that cortical input protects hypothalamic neurons from fatty acid‐induced damage, which activates PGC1α to boost mitochondrial function. This reveals a cortico‐hypothalamic axis that defends against metabolic stress.
Mengdan Tao   +10 more
wiley   +1 more source

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