Results 301 to 310 of about 96,024 (390)

Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH‐1 Migration

open access: yesGlia, Volume 73, Issue 10, Page 2077-2097, October 2025.
Main Points OECs, SCs, and Mel derive from SCPs. Sox10Cre;YapHet;TazKO mice show impaired SC maturation, reduced Mel formation, fewer SCPs, OECs, and olfactory neurons, but normal GnRH‐1 neuron migration. ABSTRACT Olfactory Ensheathing Cells (OECs) are glial cells originating from the neural crest and are critical for bundling olfactory axons to the ...
Ed Zandro M. Taroc   +7 more
wiley   +1 more source

SOX10, MITF, and microRNAs: Decoding their interplay in regulating melanoma plasticity

open access: yesInternational Journal of Cancer, Volume 157, Issue 7, Page 1277-1293, 1 October 2025.
Abstract Recent studies show that the dysregulation of the transcription factor SOX10 is essential for the development and progression of melanoma. MicroRNAs (miRNAs) can regulate the expression of transcription factors at the post‐transcriptional level. The interactions between SOX10 and its targeting miRNAs form network motifs such as feedforward and
Xin Lai   +6 more
wiley   +1 more source

The Role of Glycoprotein Non‐Metastatic Melanoma Protein B (GPNMB) in Tumors and Other Diseases

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Glycoprotein non‐metastatic melanoma protein B (GPNMB) is is widely involved in biological processes such as tissues, cells, metabolism and immunity, regulates multiple signaling pathways, and plays an important role in the occurrence and development of various diseases, including tumors.
Zhenyu Wu   +5 more
wiley   +1 more source

Circular Dichroism of Active Fragments of α-Melanocyte-stimulating Hormone

open access: bronze, 1971
Kiyoshi Ikeda   +4 more
openalex   +2 more sources

Enhanced diagnostic potential of CSPG4 in melanoma and nevi: a comparative study with PRAME, CDC7 and Ki67

open access: yesThe Journal of Pathology, Volume 267, Issue 1, Page 69-78, September 2025.
Abstract Chondroitin sulfate proteoglycan 4 (CSPG4) is a promising target for melanoma immunotherapy, but its expression in benign melanocytic lesions and its diagnostic value remain unexplored. This study assessed CSPG4 expression in benign nevi (BN), dysplastic nevi (DN), and superficial spreading melanomas (SSM), comparing it with PRAME ...
Elias AT Koch   +8 more
wiley   +1 more source

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