Results 161 to 170 of about 54,942 (309)

Somatic mutations distinguish melanocyte subpopulations in human skin. [PDF]

Nat Cell Biol
Tandukar B, Deivendran D, Chen L, Bahrani N, Baskurt D, Weier B, Sharma H, Cruz-Pacheco N, Hu M, Marks K, Zitnay RG, Bandari AK, Rentroia-Pacheco B, Nekoonam R, Bastian BC, Yeh I, Judson-Torres R, Shain AH.   +17 more
europepmc   +1 more source

Cytology‐First Diagnostic Workflow for Melanoma of Unknown Primary With Molecular Profiling

Cytopathology, EarlyView.
Cytology‑first diagnostic workflow for melanoma of unknown primary. Fine‑needle aspiration of an enlarged lymph node enables rapid cytologic evaluation and immunocytochemical confirmation of melanocytic lineage (SOX10). This early cytologic diagnosis facilitates timely surgical excision and comprehensive genomic profiling, supporting integrated ...
Hong Yu, Mokhtar Abdelhammed, Xu Cao, Nisha S. Ramani   +3 more
wiley   +1 more source

Single-cell transcriptomic profiling of halo nevi and normal nevi reveals CD8⁺ T cell activation in melanocytic autoimmunity. [PDF]

Front Immunol
Gao W, Lv H, Xie Y, Chang Y, Li B, Chang J, Sun K, Chen T.   +7 more
europepmc   +1 more source

Oncogenic GNAQ and BRAF in epidermal versus non-epidermal melanocytes

, 2019
Melanocytic neoplasms represents a group of biologically distinct subtypes that display a wide phenotypic variation. An integrative taxonomy of melanocytic neoplasms have grouped them into two major clades: those that arise from epithelium-associated ...
Urtatiz Gongora, Oscar Alejandro
core  

Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi, Aurora Gaeta, Simone Ribero, Nelleke Gruis, Julia Newton‐Bishop, David Polsky, DeAnn Lazovich, Paola Ghiorzo, Gloria Ribas, Chiara Menin, Alexander J. Stratigos, Gabriella Guida, Susana Puig, Maria Concetta Fargnoli, Peter A. Kanetsky, Paola Queirolo, Vincenzo Bagnardi, Veronique Bataille, Sara Raimondi, Sara Gandini, M‐SKIP study group   +20 more
wiley   +1 more source

Psoralea corylifolia (babchi) seeds enhance proliferation of normal human cultured melanocytes: GC–MS profiling and biological investigation

Open Chemistry, 2023
Kumar Ashok, AlGhamdi Khalid M., Khan Anis Ahmed, Ahamad Rizwan, Ghadeer Abdulrahman, Bari Ahmed   +5 more
doaj   +1 more source

JAK Activation Drives MED15-Associated Melanocyte Dysfunction in Vitiligo Beyond Immune Cells. [PDF]

Clin Cosmet Investig Dermatol
Wu J, Ren Y, Cui J, He M, Zhang X, Li D, Zhang N.   +6 more
europepmc   +1 more source

Afamelanotide improves quality of life and light tolerance in Austrian erythropoietic protoporphyria patients

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Erythropoietic protoporphyria (EPP) is a rare genetic disorder characterized by severe phototoxic reactions that occur within minutes of light exposure. In clinical studies, afamelanotide has been shown to prolong pain‐free sun exposure, improve quality of life, and reduce the frequency and severity of phototoxic reactions ...
Magdalena Seidl‐Philipp, Hanna Schratter, Johanna Auer, Gerold Schwantzer, Maximilian Lammer, Philipp Hinteregger, Ines Vergeiner, Robert Gruber, Peter Wolf, Angelika Hofer   +9 more
wiley   +1 more source

Aberrant laminin signaling drives melanocyte dedifferentiation and unveils a tractable therapeutic target in vitiligo. [PDF]

Nat Commun
Yang F, Yang L, Lai S, Yokota M, Kuroda Y, Yuki T, Takahashi Y, Sayo T, Namiki T, Goto H, Hiroyasu S, Sano S, Inoue S, Mizukami Y, Tsuruta D, Katayama I.   +15 more
europepmc   +1 more source

Antioxidant pattern in uveal melanocytes and uveal melanoma cell cultures.

, 1999
PURPOSE: To investigate the antioxidant status of cultured uveal melanocytes from patients with uveal melanoma and uveal melanoma cells to characterize some of the biochemical properties of these cells in respect to the normal cutaneous melanocytes ...
MARESCA V, PICARDO M., BLASI MA, ROCCELLA M, BALESTRAZZI E, ROCCELLA F, GRAMMATICO, Paola   +6 more
core