Results 171 to 180 of about 54,942 (309)

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

Equine Veterinary Education, EarlyView.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken, H. Tyra, M. Vetter, K. Kiger, S. Rao, L. Bass   +5 more
wiley   +1 more source

Messing with cancer therapy: how the melanoma phenotype predicts checkpoint inhibitor response

Signal Transduction and Targeted Therapy
Svenja Meierjohann, Corine Bertolotto
doaj   +1 more source

Decoding Hyperpigmentation from Biological Mechanisms to Actives with Clinically Proven Topical Efficacy: A Narrative Review. [PDF]

Dermatol Ther (Heidelb)
Duval C, Qiu J, Warrick E, Sextius P, Castiel-Higounenc I, Xiang L, Bernerd F, Passeron T.   +7 more
europepmc   +1 more source

Adult human epidermal melanocytes for neurodegeneration research

Neuronal models for Alzheimer\u27s disease research frequently have limitations as a result of their nonhuman origin and/or transformed state. Here we examined the potential of readily accessible neural crest-derived human epidermal melanocytes isolated ...
Papageorgiou N, Tobin DJ, Scally AJ, Carpenter E   +3 more
core  

Equine eyelid reconstruction by semi‐circular skin flap blepharoplasty

Equine Veterinary Education, EarlyView.
Summary Reconstructive surgeries of the equine eyelid carry significant challenges for the equine surgeon, due to the poorly mobile and tightly adhered facial skin in this species. Preservation of lid function is an essential surgical consideration in order to maintain protection of the globe and cornea and to provide ocular comfort to the case ...
V. J. Jordan, D. Leong, C. Hartley
wiley   +1 more source

Regulatory T cells in vitiligo: a review of functional disequilibrium between peripheral blood and lesional tissue. [PDF]

Front Immunol
Qiu Y, He Y, Liu F.
europepmc   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

The FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris, Paraskevi Ioannou, Nikolaos A. Afratis   +2 more
wiley   +1 more source

PRAME Expression in Melanoacanthomas: Expanding the Spectrum of Positive Melanocytes in Sun-Exposed Skin. [PDF]

Dermatopathology (Basel)
Fortarezza F, Poputchikova A, Pezzuto F, Ciolfi C, Guzzardo V, Del Fiore P, Cazzato G, Bassetto F, Alaibac M, Dei Tos AP.   +9 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Hypopigmented Patches in an Adolescent: A Diagnostic Dilemma and the Value of Clinical Restraint. [PDF]

Cureus
Naidnur S, Martes-Villalobos C, Burningham K, Gammon B, Chaudhari S, Lin R.   +5 more
europepmc   +1 more source