Results 151 to 160 of about 54,942 (309)

An ultrastructural study of intramuscular melanocytes in PET/Wmr mice

, 1978
An examination of the lateral head of the gastrocnemius of the PET/Wn!.r mouse was made with an electron microscope. Cells of the perimysium and endomysium were described and the relationship of these cells to muscle cells was characterized.
Gomer, Charles August
core  

Novel Postzygotic Variants Associated With Hypomelanosis of Ito Expand the ACTB‐Related Neurocutaneous Disease Spectrum

Clinical Genetics, EarlyView.
We describe a previously unreported phenotype related to postzygotic ACTB variants with hypomelanosis of Ito, characterized by hypopigmentation associated or not with neurodevelopmental features, distinct from Becker presentations, bridging constitutional neurodevelopmental and somatic cutaneous phenotypes.
Estella Castillon, Paul Rollier, Didier Bessis, Laurent Pasquier, Caroline Racine, Alexis Praga, Pierre Vabres, Bertille Bonniaud, Paul Kuentz, Laurence Faivre   +9 more
wiley   +1 more source

Cortical‐Hypothalamic Assembloids Uncover the Cortical Regulation of Hypothalamic Responses to Fatty Acid

Cell Proliferation, EarlyView.
By assembling cortical‐hypothalamic circuits, we show that cortical input protects hypothalamic neurons from fatty acid‐induced damage, which activates PGC1α to boost mitochondrial function. This reveals a cortico‐hypothalamic axis that defends against metabolic stress.
Mengdan Tao, Xiaowen Du, Qi Chen, Wenxin Mu, Shuning Lou, Xu Zhang, Min Xu, Jiting Li, Yuxuan Guo, Wanying Zhu, Yan Liu   +10 more
wiley   +1 more source

Circadian Clock Regulates Epidermal Endocrine System in Homeostatic Skin Pigmentation. [PDF]

Exp Dermatol
Zhu A, Yang L, Lai S, Yang F, Tsuruta D, Katayama I.   +5 more
europepmc   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Segmental Vitiligo and Somatic Mosaicism: From Pathogenesis to Therapeutics. [PDF]

Ann Dermatol
Oh J, Oh SH.
europepmc   +1 more source

Ultraviolet radiation as a double-edged regulator of melanocyte function in vitiligo therapy and melanoma carcinogenesis. [PDF]

Front Med (Lausanne)
Fan HH, Chen YY, Geng Y, Yang YF, Xu H, Xiong YY, Zheng YW, Li YM.   +7 more
europepmc   +1 more source

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Proteomic Analysis of the Metabolic Response of UVA-Exposed Melanocytes Following Co-Treatment with Cannabigerol and 3-<i>O</i>-Ethylascorbic Acid. [PDF]

Cells
Mucha M, Ryšavá A, Jarocka-Karpowicz I, Maruška A, Skrzydlewska E, Gęgotek A.   +5 more
europepmc   +1 more source

Diagnostic Utility of PRAME Immunohistochemistry for Distinguishing Acral Melanoma From Acral Melanocytic Nevi

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Introduction Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry helps distinguish non‐acral melanocytic lesions, but few studies have addressed its value in acral lesions. We aimed to identify an optimal PRAME cut‐off score to differentiate acral melanoma (AM) from acral melanocytic nevi (AMN).
Kritsada Phatcharamaneepakorn, Panitta Sitthinamsuwan, Penvadee Pattanaprichakul, Manasmon Chairatchaneeboon, Nutcha Yodrabum   +4 more
wiley   +1 more source