Results 131 to 140 of about 55,028 (307)

An ultrastructural study of intramuscular melanocytes in PET/Wmr mice [PDF]

open access: yes, 1978
An examination of the lateral head of the gastrocnemius of the PET/Wn!.r mouse was made with an electron microscope. Cells of the perimysium and endomysium were described and the relationship of these cells to muscle cells was characterized.
Gomer, Charles August
core   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

open access: yesPediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil   +2 more
wiley   +1 more source

Mélanocytes épidermiques et mélanocytes folliculaires

open access: yesGenetics Selection Evolution, 1981
Benedetto JP, Ortonne JP
doaj   +1 more source

A Large Pigmented Lesion on the Abdomen of a Woman

open access: yes
JEADV Clinical Practice, EarlyView.
Ángel Fernández‐Camporro   +2 more
wiley   +1 more source

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

open access: yesPrecision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run   +7 more
wiley   +1 more source

Post‐Traumatic Facial Macules

open access: yes
JEADV Clinical Practice, EarlyView.
Molly Papadopoullos   +3 more
wiley   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Learning Trajectories for Constructing Mechanistic Explanations and the Role Played by Epistemic Knowledge

open access: yesScience Education, EarlyView.
ABSTRACT Explaining scientific phenomena by unpacking their underlying mechanisms poses many challenges for high‐school students. One central challenge is synthesizing the different parts of a mechanism into a coherent whole and identifying what information is still missing, or whether further learning is required.
Ruth Molad, Michal Haskel‐Ittah
wiley   +1 more source

Cancer Vaccine Development: Toward Artificial Intelligence‐Assisted Personalized Cell Membrane Nanovaccine

open access: yesSmall, EarlyView.
Cancer nanovaccines have emerged as promising alternatives to conventional cancer vaccines, which have shown limited clinical efficacy. In particular, cell membrane nanoparticle‐based nanovaccines can offer high biocompatibility and immunogenicity while preserving tumor antigens, including antigen repertoires.
Munsik Kim, Ilkoo Noh
wiley   +1 more source

When Pigment Loss Meets Pigment Clusters: Vitiligo in a Congenital Speckled Lentiginous Nevus

open access: yesIndian Journal of Paediatric Dermatology
Vitiligo, an acquired disorder, manifests as depigmented patches on the skin due to the selective destruction of melanocytes. Congenital speckled lentiginous nevus (CSLN), also known as nevus spilus, is a benign pigmented skin lesion present at birth or ...
Vivek Narendrasingh Salame   +3 more
doaj   +1 more source

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