Results 121 to 130 of about 54,942 (309)

Melanocytes, Melanocytic Nevi, and Progression to Melanoma [PDF]

, 2020
Benign melanocytic nevi form when melanocytes that acquire a BRAFV600E mutation undergo a period of rapid proliferation followed by subsequent growth-arrest.
McNeal, Andrew Scott
core  

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Pigmented Melanocytes Are Protected Against Ultraviolet-A-Induced Membrane Damage

, 2003
The dominant skin pigment melanin is believed to protect human skin against several harmful effects of ultraviolet radiation. It is not clear, however, how melanin located inside melanin-producing melanocytes modulates the effect of ultraviolet radiation
Kvam, Egil, Jostein Dahle, Dahle, Jostein, Egil Kvam   +3 more
core   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Effect of Neutron Radiation on ¹⁰BPA-Loaded Melanoma Spheroids and Melanocytes

Cells
Melanoma is an aggressive disease that arises from mutations in the cells that produce the pigment melanin, melanocytes. Melanoma is characterized by a high mortality rate, due to avoidance of applied therapies and metastasis to other organs.
Monika Szczepanek, Michał Silarski, Agnieszka Panek, Anna Telk, Katarzyna Dziedzic-Kocurek, Gabriele Parisi, Saverio Altieri, Ewa Ł. Stępień   +7 more
doaj   +1 more source

Human melanocytes express functional Toll-like receptor 4.

, 2008
BACKGROUND: Melanocytes are not simply pigment-producing cells, but produce substances with a range of biological functions including antimicrobial defense.
Jin, SH, Ahn, JH, Joo Hee Ahn, Tae Jun Park, Hee Young Kang, Kang, HY, Sun Hee Jin, Park, TJ   +7 more
core   +1 more source

Updating Traumatic Brain Injury Classification for Surgeons: Integrating the CBI‐M Framework Into Trauma and Acute Care Practice

World Journal of Surgery, EarlyView.
Traumatic brain injury (TBI) remains a major cause of death and disability worldwide. Traditional classification based on the Glasgow Coma Scale (GCS) provides a shared clinical language but insufficiently captures the biological heterogeneity, imaging variability, and contextual modifiers that influence outcomes.
Ruben Peralta, Santiago Cardona‐Collazos, Ali Msheik, Wendy D. Gonzalez, Andrés Salazar Restrepo, Laura M. Loaiza‐Cardona, Andres M. Rubiano   +6 more
wiley   +1 more source

Recurrence of Breast Cancer With Scalp Metastasis

The Kaohsiung Journal of Medical Sciences, EarlyView.
Yi‐Nan Zhu, Wan‐Chen Lu, Zi‐Yue Wang, Xu‐Yong Lin   +3 more
wiley   +1 more source

Effect of oxygen and nanoparticles on human skin and colon cells exposed to synchrotron‐based X‐ray FLASH beams

Journal of Synchrotron Radiation, EarlyView.
Most cancer patients will be treated by radiotherapy, and recent findings suggest that delivering radiation at `FLASH' ultra‐high dose rates reduces damage to healthy tissues while still damaging the tumour. This project experimentally validates the reduced healthy tissue damage of FLASH radiotherapy on cells using synchrotron‐based beams, which will ...
Moshi Geso, Matthew Cameron, Tom Ffrench, Helen Forrester, Rod Lynch, Masao Nakayama, William Patterson, Wan Nordiana Rahman, Duncan Butler, Terrence J. Piva   +9 more
wiley   +1 more source

Mélanocytes épidermiques et mélanocytes folliculaires

Genetics Selection Evolution, 1981
Benedetto JP, Ortonne JP
doaj   +1 more source