Results 101 to 110 of about 59,400 (251)

Structure and function of melanocytes, Microscopic [PDF]

, 1995
Melanocytes characterized by their tyrosinase activity, melanosomes and dendrites locate in the basa1 layer of epidermis and hair bulb in the skin of mice.
Hirobe, T.
core  

The nature of miniature melanocytes in murine epidermis [PDF]

, 1973
In the epidermis of PET/Wmr mice the population of melanocytes reaches a peak and begins to decline during the first postnatal week, and has disappeared within four weeks.
Earnhardt, John Thomas
core   +1 more source

LC‐OCT Features in Vitiligo: A Preliminary Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Vitiligo is a chronic depigmenting disorder characterized by the selective loss of melanocytes, leading to the progressive development of hypopigmented macules and patches. Line‐field confocal optical coherence tomography (LC‐OCT) is a novel imaging technique that combines the advantages of optical coherence tomography (OCT) and ...
Gerardo Palmisano, Daniele Omar Traini, Lorenzo Maria Pinto, Alessandra D'Amore, Mariano Suppa, Alessandro Di Stefani, Ketty Peris   +6 more
wiley   +1 more source

Cutaneous Pigmentary Changes During Setmelanotide Therapy: Dermoscopic and Confocal Findings in Two Patients

JEADV Clinical Practice, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4 receptor agonist approved for the treatment of rare forms of genetic obesity. Through off‐target activation of the melanocortin‐1 receptor, it may induce cutaneous pigmentation changes; however, data regarding its effects on melanocytic nevi remain limited.
Martina Cavicchi, Claudia Lasagni, Silvana Ciardo, Francesca Giusti, Albino Eccher, Caterina Longo   +5 more
wiley   +1 more source

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni, Niccolò Capurro, Alessandro Svizzero, Valeria Brazzelli   +3 more
wiley   +1 more source

Establishment of Primary Cell Cultures from Canine Oral Melanomas via Fine-Needle Aspiration: A Novel Tool for Tumorigenesis and Cancer Progression Studies

Animals
Oral melanomas are the most common oral malignancies in dogs and are characterized by an aggressive nature, invasiveness, and poor prognosis. With biological and genetic similarities to human oral melanomas, they serve as a valuable spontaneous ...
Adriana Lo Giudice, Ilaria Porcellato, Martina Pellegrini, Sven Rottenberg, Chang He, Alfredo Dentini, Giulia Moretti, Monica Cagiola, Luca Mechelli, Elisabetta Chiaradia, Chiara Brachelente   +10 more
doaj   +1 more source

Isolation, culture, and transfection of melanocytes

, 2014
Located in the basal epidermis and hair follicles, melanocytes of the integument are responsible for its coloration through production of melanin pigments. Melanin is produced in lysosomal-like organelles called melanosomes.
Joanna T. Castle, Keith, W. Nicol, Sviderskaya, Elena V., Elena V. Sviderskaya, Kohli, Jaskaren S., Claire J. Cairney, W. Nicol Keith, Philip S. Goff, Lauren S. Godwin, Goff, Philip S., Godwin, Lauren S., Castle, Joanna T., Dorothy C. Bennett, Jaskaren S. Kohli, Bennett, Dorothy C., Cairney, Claire J.   +15 more
core   +1 more source

Nail Toxicities Associated With Anticancer Therapies in Children

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley   +1 more source

MECHANISMS OF DIFFERENTIATION IN MELANOMA-CELLS AND MELANOCYTES [PDF]

, 1989
Bennett, DC, Dorothy C. Bennett
core   +1 more source

Vitiligo and Skin Cancer Risk: A Systematic Review and Meta‐Analysis With Subtype and Phototherapy Stratification

JEADV Clinical Practice, EarlyView.
Vitiligo was associated with directionally lower odds of melanoma and non‐melanoma skin cancer in this systematic review and meta‐analysis of 14 studies. A statistically significant inverse association was observed for squamous cell carcinoma. Phototherapy exposure showed higher, but non‐significant, point estimates for melanoma and non‐melanoma skin ...
Simonetta I. Gaumond, Luis F. Andrade, Peyton V. Warp, Isabella Kamholtz, Sophie Shrestha, Hannah Metheny, Alireza Abdshah, Paolo Romanelli, Joaquin J. Jimenez   +8 more
wiley   +1 more source