Results 101 to 110 of about 55,028 (307)

Human melanocytes express functional Toll-like receptor 4. [PDF]

, 2008
BACKGROUND: Melanocytes are not simply pigment-producing cells, but produce substances with a range of biological functions including antimicrobial defense.
Jin, SH, Ahn, JH, Joo Hee Ahn, Tae Jun Park, Hee Young Kang, Kang, HY, Sun Hee Jin, Park, TJ   +7 more
core   +1 more source

Establishment of reproducible method for production of cultured epidermal sheets with controlled melanocyte density

Regenerative Therapy
Introduction: Vitiligo, the most common human pigmentary disorder, significantly impacts patients' quality of life through its profound psychological and social consequences.
Mai Mori, Chie Kobori, Ryo Takagi, Moeka Tani, Hidenori Akutsu, Akihiro Umezawa   +5 more
doaj   +1 more source

Melanocyte Mitogens Induce Both Melanocyte Chemokinesis and Chemotaxis

Journal of Investigative Dermatology, 1995
It is believed that during repigmentation of vitiligo, inactive melanocytes in the outer root sheath of the hair follicle become activated, proliferate, and migrate into the depigmented skin. However, the mechanisms controlling melanocyte migration remain to be elucidated.
Horikawa, Tatsuya, Norris, David A., Yohn, Joseph J., Zekman, Tamara, Travers, Jeffrey B., Morelli, Joseph G.   +5 more
openaire   +2 more sources

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Melanoma Cells Exposed to Clomiphene Citrate Respond With Cell Cycle Arrest and Reduced Invasiveness

Journal of Applied Toxicology, EarlyView.
ABSTRACT Epidemiological studies have suggested that clomiphene citrate (CC) exposure may increase the risk of malignant melanoma, but mechanisms are unknown. We investigated the effects of CC on melanoma cell line A375. Cells were treated with CC at 2, 20, 200, and 2000 ng/mL, followed by assessment of cell viability and metabolism, cell cycle ...
Thaís S. Ribeiro, Felipe H. S. Silva, Ana Paula G. S. Miranda, Isabella T. Borges, Pedro H. D. M. Prazeres, Marcia C. F. Ferreira, Enio Ferreira, Fernando M. Reis, Helen L. Del Puerto   +8 more
wiley   +1 more source

Photobiology of Epidermal Melanocytes [PDF]

, 2019
Detecting and responding to sunlight is a basic requirement of nearly all life forms. But how the skin, a principal organ to receive sunlight, precisely detects and responds to light remains poorly understood.
Law, Brandon M.
core  

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

The nature of miniature melanocytes in murine epidermis [PDF]

, 1973
In the epidermis of PET/Wmr mice the population of melanocytes reaches a peak and begins to decline during the first postnatal week, and has disappeared within four weeks.
Earnhardt, John Thomas
core   +1 more source

Apigenin and Phloretin Combination for Skin Aging and Hyperpigmentation Regulation

Cosmetics
Melasma is a pathology with multifactorial causes that results in hyperpigmentation of sun-exposed areas, particularly facial skin. New treatments targeting the different factors regulating this condition need to be effective with and have limited ...
Alfredo Martínez-Gutiérrez, Javier Sendros, Teresa Noya, Mari Carmen González   +3 more
doaj   +1 more source

Melanocyte response following depigmentation by cryosurgery and mucosal excision: A comparative clinical and histopathological study

Contemporary Clinical Dentistry, 2019
Aims: The main aim of this study was to evaluate the melanocyte response following depigmentation by cryosurgery and mucosal excision at both clinical and histopathological levels during 6 months.
Gautami S Penmetsa, Anudeep Mopidevi, C D Dwarakanath, M A. K. V. Raju   +3 more
doaj   +1 more source