Results 91 to 100 of about 59,400 (251)

Membrane lipid metabolism as a regulatory frontier in neural crest biology: Roles for sphingolipids, cholesterol, and lipid rafts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini   +2 more
wiley   +1 more source

Histochemical Study of Melanocytes and Langerhans Cells in Trichrome Non-Segmental Vitiligo [PDF]

open access: yesInternational Journal of Medical Arts
Background: Vitiligo is a frequent acquired depigmenting disorder that causes significant psychological stress.The aim of the work: This study aimed to study the histopathological changes in the trichrome skin area together with other signs of the ...
Shaker Mahmoud El-Sayed Ezz El-din   +2 more
doaj   +1 more source

Three mutations in SASH1 cause the pathogenesis of dyschromatosis universalis hereditaria (DUH) [PDF]

open access: yes, 2011
Dyschromatosis universalis hereditaria (DUH) is a rare genodermatosis characterized by hyper- and hypopigmented macules which form a reticulate or mottled pattern.
Zhiyun Wei, Qinghe Xing, Dingan Zhou
core  

Melanocytes: the new Black.

open access: yes, 2007
Melanocytes, pigment-producing cells residing primarily in the hair follicle, epidermis and eye, are responsible for skin hair and eye pigmentation.
Goding, CR
core   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister   +13 more
wiley   +1 more source

Dysregulated Intracellular Signaling in the Pathogenesis of Vitiligo: An Update on Emerging Therapeutic Strategies

open access: yesBiomedicines
Vitiligo is an acquired depigmentation disorder characterized by the selective destruction of melanocytes, resulting in the progressive loss of pigment in the skin and hair. This condition frequently leads to significant psychological distress.
Ramona Marrapodi   +2 more
doaj   +1 more source

Methylcobalamin Protects Melanocytes from H2O2-Induced Oxidative Stress by Activating the Nrf2/HO-1 Pathway

open access: yesDrug Design, Development and Therapy, 2021
Ran An,1,2 Dong Li,1 Yingying Dong,1 Qiuyun She,1 Ting Zhou,1 Xiaoqi Nie,1 Ronghua Pan,1 Yunhua Deng1 1Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of ...
An R   +7 more
doaj  

Visceral Peritoneum Hyperpigmentation in Chickens Is Associated with DCT Expression

open access: yesAnimals
Hyperpigmentation of the visceral peritoneum (HVP) is a pigmentation abnormality in chickens that adversely affects carcass appearance, consumer acceptance, and poultry production. However, the genetic basis of HVP remains unclear.
Xu Dong   +7 more
doaj   +1 more source

Impact of lomefloxacin on antioxidant enzymes activity in normal melanocytes HEMa-LP

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2012
Lomefloxacin is a synthetic, broad-spectrum antibacterial antibiotic. The use of this drug in the treatment of various infections may be limited by inherent serious adverse effects on pigmented tissues.
Artur Beberok   +3 more
doaj   +1 more source

The effects of royal jelly on human health: A narrative review of clinical studies

open access: yesJSFA reports, EarlyView.
Abstract Royal jelly (RJ) is a natural bioactive substance with documented effects on human health. This narrative review synthesizes evidence from clinical and clinically relevant experimental studies evaluating the therapeutic potential of RJ.
Georgios Goras   +2 more
wiley   +1 more source

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