Results 71 to 80 of about 55,028 (307)

Novel uveal Melanocyte cell lines display distinct features from uveal melanoma

Advances in Ophthalmology Practice and Research
Purposes: Despite advances in prognostication for uveal melanoma (UM), mortality from this disease remains high due to a lack of effective treatments to prevent metastatic progression.
Lauren A. Dalvin, Piotr K. Kopinski, David R. Miley, Hien Ong, Samantha A. Erickson, Cynthia M. Andrews-Pfannkoch, Stephanie D. Burr, James A. Armitage   +7 more
doaj   +1 more source

A Lethal Progressive Neuroinflammation Disguised as MOGAD Revealing a Final Diagnosis of Griscelli Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
Chiara Veredice, Chiara Arpaia, Ilaria Contaldo, Anna Capasso, Donato Rigante   +4 more
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

Biologic characteristics of cultured human vitiligo melanocytes. [PDF]

, 1994
BACKGROUND: Vitiligo is a pigmentary disorder of unknown cause characterized by depigmented patches due to destruction of melanocytes. Recently, the inherent cellular defect theory has been discussed.
Kim, HI, Park, YK, Kim, NS, Im, S, Hann, SK   +4 more
core  

Phagocytosis by normal human melanocytes in vitro [PDF]

, 1993
Phagocytosis is an important first step in processing of antigens ultimately to be presented in the context of MHC class II molecules on the cell surface.
Dutrieux, R. P., Verkruisen, R. P., Westerhof, W., Le Poole, I. C., Dingemans, K. P., Das, P. K., van den Wijngaard, R. M.   +6 more
core   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

Comparison of SOX-10, HMB-45, and Melan-A in Benign Melanocytic Lesions

Clinical, Cosmetic and Investigational Dermatology, 2021
Sabrina E Dass,1 Taryn Huizenga,2 Mehdi Farshchian,2 Darius R Mehregan2 1Wayne State University School of Medicine, Detroit, MI, USA; 2Department of Dermatology, Wayne State University, Detroit, MI, USACorrespondence: Mehdi FarshchianDepartment of ...
Dass SE, Huizenga T, Farshchian M, Mehregan DR   +3 more
doaj  

Electrocardiographic and Skin Manifestations of Turner Syndrome: Association With Cardiovascular Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Congenital heart disease (CHD) and dermatologic conditions such as lymphedema and acquired melanocytic nevi (AMN) are common in Turner Syndrome (TS). We hypothesized that abnormalities of cranial neural crest cell derivatives drive the skin and heart manifestations of TS. We conducted joint cardiac and skin examinations of volunteers at a 2023
Sarah Elsaim, Brett Vernier, Van Thi Thanh Truong, Riya T. Patel, Matthew Brown, Martin Chacon Portillo, Megan Rogge, David Rodriguez‐Buritica, Siddharth K. Prakash   +8 more
wiley   +1 more source

Bace2 in normal and malignant melanocytes [PDF]

, 2017
BACE2 is a gene encoding an aspartic protease called beta-site APP cleaving enzyme-2 that has been shown to cleave PMEL and Tmem27 in mice43,40. The bace2 homozygous zebrafish mutant, in which a point mutation leads to a premature stop codon, shows a ...
Zimmer, Milena A.
core   +3 more sources

Hair follicle-derived melanocyte transplant as a promising treatment strategy for vitiligo

Stem Cell Research & Therapy
Background The global incidence of vitiligo has been increasing in recent years, imposing psychological distress and social pressure owing to its refractory and recurrent nature.
Ruirui Fan, Jie Gao, Jin Chen
doaj   +1 more source