Results 61 to 70 of about 55,028 (307)

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

In vitro culture and tissue-derived specific expression of melanocytes from ovary of adult Silky Fowl

Poultry Science
: The presence of a significant number of melanocytes in the ovary and follicular membrane of Silky Fowl suggests their potential involvement in follicle development.
Yurong Tai, Deping Han, Xue Yang, Ganxian Cai, HuaiYu Li, Yuanyuan Zhang, Junying Li, Xuemei Deng   +7 more
doaj   +1 more source

Melanocytes, melanocyte stem cells, and melanoma stem cells [PDF]

Clinics in Dermatology, 2013
Melanocyte stem cells differ greatly from melanoma stem cells; the former provide pigmented cells during normal tissue homeostasis and repair, and the latter play an active role in a lethal form of cancer. These 2 cell types share several features and can be studied by similar methods.
Deborah, Lang, Joseph B, Mascarenhas, Christopher R, Shea   +2 more
openaire   +2 more sources

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

Molecular and cellular pathogenesis of melanoma initiation and progression [PDF]

, 2013
Melanoma is a malignant tumour of melanocytes, which can spread to other organs of the body resulting in severe and/or lethal malignancies. Melanocytes are pigment producing cells found in deep layer of the epidermis and are originated from melanocytes ...
Regad, T
core   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

An Investigation of Autoantibodies against Tyrosine Hydroxylase in Patients with Vitiligo [PDF]

, 2012
Vitiligo is an acquired idiopathic hypomelanotic skin disorder characterised by depigmented macules due to loss of cutaneous melanocytes. Evidence suggests that autoimmunity plays a role in the pathogenesis of the disease, since antibodies and T cells ...
Rahoma, Sherif
core  

Isolation, culture, and transfection of melanocytes [PDF]

, 2014
Located in the basal epidermis and hair follicles, melanocytes of the integument are responsible for its coloration through production of melanin pigments. Melanin is produced in lysosomal-like organelles called melanosomes.
Joanna T. Castle, Keith, W. Nicol, Sviderskaya, Elena V., Elena V. Sviderskaya, Kohli, Jaskaren S., Claire J. Cairney, W. Nicol Keith, Philip S. Goff, Lauren S. Godwin, Goff, Philip S., Godwin, Lauren S., Castle, Joanna T., Dorothy C. Bennett, Jaskaren S. Kohli, Bennett, Dorothy C., Cairney, Claire J.   +15 more
core   +1 more source

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

Advanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan, Yaqing Wen, Yushan Zhang, Lan Zhang, Jianjian Zhu, Zhen Tang, Ling Jiang, Chuhan Fu, Shu Zhou, Keyi Zhang, Jiangfeng Huang, Li Lei, Jing Chen, Qinghai Zeng   +13 more
wiley   +1 more source

Mitotic Activity of Hairless Mouse Epidermal Melanocytes: Its Role in the Increase of Melanocytes During Ultraviolet Radiation [PDF]

, 1972
Using split epidermal sheets treated with colchicine, a quantitative study was carried out on hairless mouse epidermal melanocytes and those in mitosis, during 14 daily exposures to UV.
Sato, Takehiko, Kawada, Akihiro, Sato, T, Kawada, A   +3 more
core   +1 more source