Results 281 to 290 of about 85,786 (342)

Molecular insights into region-specific sexual dichromatism: Comparative transcriptome analysis of red cheek pigmentation in zebra finches. [PDF]

PLoS Genet
Lin GW, Chen CK, Jiang TX, Liang YC, Tang PC, Wu P, Widelitz RB, Chen CF, Chuong CM.   +8 more
europepmc   +1 more source

Improvement of the Anticancer Efficacy of PD‐1/PD‐L1 Blockade: Advances in Molecular Mechanisms and Therapeutic Strategies

MedComm, Volume 6, Issue 8, August 2025.
Mechanisms of alleviating resistance to PD‐1/PD‐L1 blockade by IFN‐α and IFN‐β. In these mechanisms, the “yin‐yang balance” is disrupted, thus preventing T cells from attacking cancer cells. Restoring this balance may improve the efficacy of anti‐PD‐1/PD‐L1 therapy and reinvigorate T cells and other immune cells to target and destroy cancer cells ...
Peng Gao, Xiao Li, Zhenyu Duan, Yang Wang, Yinggang Li, Jing Wang, Kui Luo, Jie Chen   +7 more
wiley   +1 more source

Research progress on pathogenesis of skin pigmentation in chronic liver disease. [PDF]

Biomol Biomed
Liu T, Xi T, Dong X, Xu D.
europepmc   +1 more source

Clinicopathologic Features, Management, and Outcomes Of Pediatric CRTC1::TRIM11 and MED15::ATF1 Tumors With Spitzoid Morphology: A Case Series

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Limited information is available on the clinicopathologic features and management of pediatric CRTC1::TRIM11 (CTRTs) and MED15::ATF1‐rearranged tumors (MARTs). In this series of pediatric CTRTs (n = 5) and MARTs (n = 2), all tumors exhibited spitzoid morphology and expressed melanocytic markers.
Michael R. Sargen, Madeline H. Fitzhugh, Jennifer S. Ko, Allison G. Close, Sara C. Horton, Faizan Malik, Larissa V. Furtado, Armita Bahrami, Brittani K. N. Seynnaeve, Alberto S. Pappo, Vincent Liu, Kevin Cheung, Svetlana D. Pack, Liqiang Xi, Mark Raffeld, Ina Lee, Jeffrey Gagan, Kenneth Aldape, Frederic G. Barr, Stephen M. Hewitt, Christina K. Ferrone, Anna Hayden, Jessica N. Hatton, Alisa M. Goldstein, Ruth M. Pfeiffer, Brigitte Widemann, Mary Frances Wedekind Malone, Andrea M. Gross, Rosandra Kaplan, Marielle E. Yohe, Kristen G. Berrebi   +30 more
wiley   +1 more source

Atypical lentigo maligna melanoma of the chin: A case report. [PDF]

JAAD Case Rep
Ghalili S, Day D, Adalsteinsson JA, Taub P, Lee DS, Lewin JM.   +5 more
europepmc   +1 more source

Dermoscopic Features and Their Association With Breslow Thickness of Facial Lentigo Maligna in Koreans: A Multi‐Center Retrospective Study

The Journal of Dermatology, Volume 52, Issue 8, Page 1243-1254, August 2025.
ABSTRACT Background Owing to the rarity of lentigo maligna (LM) and lentigo maligna melanoma (LMM) in East Asians, their dermoscopic features are underreported. The prognosis and management of LM and LMM depend on the Breslow thickness (BT). However, the association between BT and the dermoscopic features of LMM is largely unknown. Objectives To report
Jinie Lee, Ji Su Lee, Jun Young Kim, Jung Min Bae, Jin Park, Je‐Ho Mun   +5 more
wiley   +1 more source

Do Melanocytes Have a Role in Controlling Epidermal Bacterial Colonisation and the Skin Microbiome? [PDF]

Exp Dermatol
Bi O, Caballero-Lima D, Sikkink S, Westgate G, Kauser S, Elies J, Thornton MJ.   +6 more
europepmc   +1 more source

Strong Signatures of Selection on Candidate Genes Underlying Core Speciation Mechanisms in Desert Tortoises

Molecular Ecology Resources, Volume 25, Issue 6, August 2025.
ABSTRACT Genomic incompatibilities and differential ecological adaptation are thought to be fundamental mechanisms of speciation. In this study, we generated a chromosome‐scale reference genome and annotation for Gopherus morafkai , the Sonoran Desert tortoise, and conducted a detailed analysis of genes under positive selection with its sister species,
Sarah M. Baty, Raúl Araya‐Donoso, Avery Paulsen, Avery Williams, Dale F. DeNardo, Kenro Kusumi, Greer A. Dolby   +6 more
wiley   +1 more source

Down-Regulation of HLA-C Expression on Melanocytes May Contribute to the Therapeutic Efficacy of UVB Phototherapy in Psoriasis. [PDF]

Int J Mol Sci
Arakawa Y, Arakawa A, Vural S, He M, Vollmer S, Prinz JC.   +5 more
europepmc   +1 more source

Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti‐PD1 resistance in skin cutaneous melanoma

British Journal of Pharmacology, Volume 182, Issue 16, Page 3903-3922, August 2025.
Abstract Background and Purpose Immune checkpoint inhibitors, such as anti­PD1, revolutionized melanoma treatment. However, resistance and low response rates remain problems. Our goal was to pinpoint actionable biomarkers of resistance to anti‐PD1 treatment and verify therapeutic effectiveness in vivo.
Szonja Anna Kovács, Tamás Kovács, András Lánczky, Ágnes Paál, Zsombor I. Hegedűs, Nabil V. Sayour, Lilla Szabó, Andrea Kovács, Giampaolo Bianchini, Péter Ferdinandy, Alberto Ocana, Zoltán V. Varga, János Tibor Fekete, Balázs Győrffy   +13 more
wiley   +1 more source