Results 161 to 170 of about 170,549 (267)

CSF1R-dependent CD169-positive macrophages locally constrain melanoma growth in the skin. [PDF]

J Exp Med
Keith YH, Duchini E, Lin X, Kyaw W, Weninger FGP, Dhenni R, Telfser AJ, Grootveld AK, Barkauskas D, Fontaine-Titley A, Tikoo S, Jain R, Weninger W, Frew JW, Deenick EK, Brink R, Martin LK, Chtanova T, Goldstein LD, Scolyer RA, Long GV, Palendira U, Phan TG.   +22 more
europepmc   +1 more source

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathies

Arthritis &Rheumatology, Accepted Article.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo, Josefin Kenrick, Angeles S Galindo‐Feria, Antonella Notarnicola, Ana Daniela Ulloa Navas, Irene Peralta‐Garcia, Orane Demuynck, Andrea Kemp, Valérie Leclair, Karin Lodin, Eveline Van Gompel, Lara Dani, Fabricio Espinosa‐Ortega, Maryam Dastmalchi, Leonid Padyukov, Charlotta Preger, María Bueno Álvez, Mathias Uhlén, Peter Nilsson, Fredrik Edfors, Lina‐Marcela Diaz‐Gallo, Elisa Pin, Ingrid E Lundberg, Begum Horuluoglu   +23 more
wiley   +1 more source

Enhanced IFNy response in dedifferentiated melanoma cells is due to chromatin remodeling as revealed by ATAC-seq. [PDF]

Cell Commun Signal
Sævarsson T, de Lomana ALG, Sánchez Ó, Brynjólfsson SF, Steingrímsson E, Einarsdóttir BÓ.   +5 more
europepmc   +1 more source

Phantom citations: An empirical study of non‐existent and unverifiable references in scholarly literature

Journal of the Association for Information Science and Technology, EarlyView.
Abstract The integrity of scholarly communication depends critically on the accuracy and verifiability of cited references. Citations enable readers to trace prior work, assess evidence, and situate new contributions within the existing literature. However, concerns have emerged regarding the presence of references in published papers that cannot be ...
Chengcheng Han, Sathiamoorthy Manoharan, Xinfeng Ye, Ulrich Speidel   +3 more
wiley   +1 more source

IL-8 is a potential biomarker for retinal detachment secondary to choroidal melanoma. [PDF]

PeerJ
Xing Z, Zhang X, Yu W, Lei Y, Wang G, Lv H.   +5 more
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Metabolic Responses of Melanocytes and Melanoma Cells to UVA Radiation and Phytocannabinoids Exposure. [PDF]

Antioxidants (Basel)
Biernacki M, Gieniusz E, Gęgotek A, Jaganjac M, Skrzydlewska E.   +4 more
europepmc   +1 more source

Utilization of immune checkpoint inhibitors for the treatment of cancer in Scotland, 2018–2024: A national retrospective cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of the study is to describe the use of immune checkpoint inhibitors (ICIs) for the treatment of cancer in Scotland. Methods The retrospective observational cohort study included patients aged 18 years or older who commenced treatment with an ICI in Scotland between 1 January 2018 and 31 December 2024.
Tanja Mueller, Christine Crearie, Liya Lu, Jiafeng Pan, Fraser N. Sneden, David Martin, Amanj Kurdi, Catherine S. Thomson, Julie Clarke, Marion Bennie   +9 more
wiley   +1 more source

A network pharmacology and molecular docking approach to investigate the anticancer mechanism of baicalin against melanoma through induction of apoptosis via EGFR-mediated PI3K/AKT pathway. [PDF]

Transl Cancer Res
He Z, Huang A, Lv J, Zhou J, Lou W, Xu B, Wu X.   +6 more
europepmc   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source