Results 91 to 100 of about 528,594 (306)

Real-World Efficacy and Safety of Anti-PD-1 Antibody Plus Apatinib and Temozolomide for Advanced Acral Melanoma

Cancer Management and Research
Jiaran Zhang,1,* Huichun Tian,1,* Lili Mao,1 Caili Li,1 Xiaoting Wei,1 Junjie Gu,1 Xuan Wang,1 Li Zhou,2 Bin Lian,1 Bixia Tang,1 Xieqiao Yan,2 Siming Li,2 Chuanliang Cui,1 Zhihong Chi,1 Xinan Sheng,2 Jun Guo,1 Lu Si1 1Department of ...
Zhang J, Tian H, Mao L, Li C, Wei X, Gu J, Wang X, Zhou L, Lian B, Tang B, Yan X, Li S, Cui C, Chi Z, Sheng X, Guo J, Si L   +16 more
doaj  

21 | Melanoma in situ: long-term outcomes and follow-up strategies based on risk stratification

Dermatology Reports
Background: In recent years, the rising incidence of melanoma in situ (MIS) has drawn increasing attention to treatment and follow-up strategies aimed at reducing the risk of recurrence and new primary melanomas.
Italian Melanoma Intergroup
doaj   +1 more source

Integrated Visible Light and Oxidant Protection Through Multifunctional Sunscreens

Advanced Healthcare Materials, EarlyView.
High‐energy visible radiation (HEVR), although less energetic than UV light, penetrates deeper into the skin and contributes to photoaging, pigmentation disorders, and oxidative stress. The development of new HEVR‐targeted filters, therefore, represents not only a scientific challenge but also a pressing public health and cosmetic industry need.
Beatriz Peñín, Raúl Losantos, Ignacio Funes‐Ardoiz, Diego Sampedro   +3 more
wiley   +1 more source

Pharmacological Basis of Melanoma Chemotherapy

, 2022
Melanoma is the most aggressive and lethal type of skin cancer. First-line therapy for metastatic melanoma is either immune checkpoint inhibitors or BRAF/MEK inhibitors, however, chemotherapy plays an important role in palliative treatment of refractory ...
Ito, Midori
core  

20 | How Covid-19 pandemic influenced the diagnosis of new primary melanoma: a retrospective, multicenter study by the Italian Society of Oncological Surgery

Dermatology Reports
Background: Melanoma is a severe and potentially fatal skin cancer, which is particularly sensitive to delays in diagnosis and treatment (Figure 1). It has been widely demonstrated that the diagnostic delays during COVID-19 pandemic determined higher ...
Italian Melanoma Intergroup
doaj   +1 more source

Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO‐Chitosan Biointerfaces

Advanced Healthcare Materials, EarlyView.
Vapour phase metalation (VPM), multiplied pulsed vapour phase infiltration (MPI), and O2 plasma‑enhanced atomic layer deposition (PEALD) tailor Zn–chitosan (Zn‑CS) films. PEALD improves wettability and biocompatibility. MPI enhances semiconductor behavior. Antiseptic selectivity: VPM → E. coli; MPI → H. pylori.
Mabel Moreno, Anjana Devi, David Zanders, Miryam Arredondo, Davide Mariotti, Ruairi McGlynn, Sindy Devis, Simón Guerrero, Eglantina Benavente, Matias Alegría, Yusser Olguin, Lorena Lobos‐Gonzalez, Kevin Guzmán, Elizabeth Rivas‐Yañez, Paula Solar, Valentin Cepus, Michael Krause, Luis Velásquez   +17 more
wiley   +1 more source

Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. [PDF]

, 2014
The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potential.
Gabriela Kalna (192504), William J. Faller (644356), Bennett, DC, Knecht, D, Veltman, DM, Jones, R, Andrew J Muinonen-Martin, Muinonen-Martin, Andrew J, Muinonen-Martin, AJ, Lindsay, C, Faller, William J., Douwe M Veltman, Wakelam, Michael J.O., Dorothy C Bennett, David A Knecht, Owen J Sansom, Zhang, Qifeng, Faller, WJ, Michael J O Wakelam, Machesky, Laura M, Bennett, Dorothy C., Knecht, David A, Robert Jones (270787), Gabriela Kalna, Knecht, DA, Insall, Robert H, Machesky, Laura M., Smethurst, Elizabeth, Smethurst, E, Lindsay, Colin; id_orcid, Robert Jones, Lindsay, Colin, Insall, RH, Sansom, Owen J., Elizabeth Smethurst (644355), Faller, William J, Jones, Robert, Laura M Machesky, Knecht, David A., Robert H. Insall (220984), Sansom, Owen J, Andrew J. Muinonen-Martin (235328), Michael J. O. Wakelam (116384), Sansom, OJ, Machesky, LM, Machesky, Laura, Wakelam, Michael J O, Robert Herd, Insall, Robert H., Owen J. Sansom (192366), Douwe M. Veltman (220981), Veltman, Douwe M, Wakelam, MJ, Kalna, Gabriela, Elizabeth Smethurst, Muinonen-Martin, Andrew J., Susanto, Olivia, William J Faller, Colin Lindsay, Herd, R, Zhang, Q, Susanto, O, Robert H Insall, Qifeng Zhang (116382), Laura M. Machesky (175567), Bennett, Dorothy C, Kalna, G, Robert Herd (644358), Olivia Susanto (644354), Colin Lindsay (644357), Qifeng Zhang, Herd, Robert, Dorothy C. Bennett (234520), David A. Knecht (231111), Olivia Susanto, Veltman, Douwe M., Bennett, Dorothy   +76 more
core   +1 more source

13 | Spatial contexture of tertiary lymphoid structures as a predictor of recurrence in early-stage melanoma

Dermatology Reports
Background: Tertiary Lymphoid Structures (TLS) are organized aggregates of immune cells that form in non-lymphoid tissues in response to chronic inflammation, including cancer.
Italian Melanoma Intergroup
doaj   +1 more source

Matrix Stiffness Directs Stemness Signatures in Breast Cancer

Advanced Healthcare Materials, EarlyView.
We built lab‐grown breast cancer models to study how the stiffness of the tumor's surroundings influences cancer behavior. Softer environments encouraged more stem‐like, drug‐resistant cells, while stiffer ones kept cells more differentiated. These findings show that tissue mechanics drive cancer diversity and drug resistance, offering new insights for
Chantal Kopecky, Elvis Pandzic, Sean Porazinski, J Justin Gooding, Kristopher A Kilian   +4 more
wiley   +1 more source

TP63 is implicated in apoptotic dysregulation in melanoma

, 2010
PhDCutaneous melanoma is an aggressive malignancy accounting for 4% of skin cancers but 80% of all skin-cancer related deaths. Its incidence is rapidly rising and advanced disease is notoriously treatment-resistant.
Matin, Rubeta N H
core