Results 91 to 100 of about 593,039 (291)

Melanoma clinicamente sporadico: valutazione del ruolo di altri parametri oltre l'anamnesi familiare come indicatori di suscettibilità genetica ed applicazione a protocolli di prevenzione mirata al nucleo familiare.

, 2003
Melanoma clinicamente sporadico - anamnesi familiare - suscettibilità genetica - protocolli di prevenzione per nucleo ...
MANTELLI M, INTERGRUPPO MELANOMA ITALIANO, BIANCHI, GIOVANNA, VERCELLI, MARINA, CASELLA C   +4 more
core   +1 more source

21 | Melanoma in situ: long-term outcomes and follow-up strategies based on risk stratification

Dermatology Reports
Background: In recent years, the rising incidence of melanoma in situ (MIS) has drawn increasing attention to treatment and follow-up strategies aimed at reducing the risk of recurrence and new primary melanomas.
Italian Melanoma Intergroup
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Real-World Efficacy and Safety of Anti-PD-1 Antibody Plus Apatinib and Temozolomide for Advanced Acral Melanoma

Cancer Management and Research
Jiaran Zhang,1,* Huichun Tian,1,* Lili Mao,1 Caili Li,1 Xiaoting Wei,1 Junjie Gu,1 Xuan Wang,1 Li Zhou,2 Bin Lian,1 Bixia Tang,1 Xieqiao Yan,2 Siming Li,2 Chuanliang Cui,1 Zhihong Chi,1 Xinan Sheng,2 Jun Guo,1 Lu Si1 1Department of ...
Zhang J, Tian H, Mao L, Li C, Wei X, Gu J, Wang X, Zhou L, Lian B, Tang B, Yan X, Li S, Cui C, Chi Z, Sheng X, Guo J, Si L   +16 more
doaj  

20 | How Covid-19 pandemic influenced the diagnosis of new primary melanoma: a retrospective, multicenter study by the Italian Society of Oncological Surgery

Dermatology Reports
Background: Melanoma is a severe and potentially fatal skin cancer, which is particularly sensitive to delays in diagnosis and treatment (Figure 1). It has been widely demonstrated that the diagnostic delays during COVID-19 pandemic determined higher ...
Italian Melanoma Intergroup
doaj   +1 more source

Clinical guidelines for the recognition of melanoma of the foot and nail unit [PDF]

, 2010
Malignant melanoma is a life threatening skin tumour which may arise on the foot. The prognosis for the condition is good when lesions are diagnosed and treated early.
David AR de Berker, Bristow, I.R., de Berker, D.A.R., Turner Richard J, Bristow Ivan R, Katharine M Acland, Richard J Turner, Jonathan Bowling, Ivan R Bristow, Acland Katharine M, de Berker David AR, Bowling, J., Turner, R.J., Acland, K. M., Bowling Jonathan   +14 more
core   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

13 | Spatial contexture of tertiary lymphoid structures as a predictor of recurrence in early-stage melanoma

Dermatology Reports
Background: Tertiary Lymphoid Structures (TLS) are organized aggregates of immune cells that form in non-lymphoid tissues in response to chronic inflammation, including cancer.
Italian Melanoma Intergroup
doaj   +1 more source

MDM2 SNP309 promoter polymorphism confers risk for hereditary melanoma

, 2014
The p53 pathway regulates stress response, and variations in p53, MDM2, and MDM4 may predispose an individual to tumor development. The aim of this study was to study the impact of genetic variation on sporadic and hereditary melanoma. We have analyzed a
Stjernstrom, Annika,, Rosdahl, Inger,, Enerbäck, Charlotta,, Fredrikson, Mats,, Bivik, Cecilia,, Wäster, Petra,, Thunell, Lena,, Synnerstad, Ingrid,   +7 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source