Results 121 to 130 of about 593,039 (291)
Background: Cutaneous melanoma is a leading cause of cancer-related mortality despite accounting for a minority of skin cancers. Early diagnosis is crucial, and dermoscopy has markedly improved diagnostic sensitivity compared with clinical examination ...
Italian Melanoma Intergroup
doaj +1 more source
Synchronized Ablation of Multifocal Tumors Enabled by Multi‐Channel Lanthanide Nanocomposites
A multi‐channel lanthanide nanocomposite enables orthogonal monitoring of tumor pH, glutathione, and temperature to guide customized therapy. Real‐time luminescence readouts determine a single irradiation protocol that synchronizes drug release and photothermal treatment, allowing efficient ablation of multifocal tumors while minimizing overtreatment ...
Fang Li +6 more
wiley +1 more source
05 | Revisiting cancer risk associated with the MITF p.e318k variant beyond melanoma
Background: The p.E318K variant of the Melanocyte Inducing Transcription Factor (MITF) has been implicated in genetic predisposition to melanoma as an intermediate penetrance allele.
Italian Melanoma Intergroup
doaj +1 more source
Biomass DNA: An Emerging Building Block for Advanced Materials
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley +1 more source
04 | Association of a novel TERT polymorphism with poorer survival in male patients with melanoma
Background: In recent years, several genes beyond BRAF have been identified as recurrently mutated in melanoma, including TERT (telomerase reverse transcriptase). While the most extensively studied TERT alterations occur in its promoter region, intron 4
Italian Melanoma Intergroup
doaj +1 more source
Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang +11 more
wiley +1 more source
Background: General practitioners play a crucial role in the early detection and prevention of cutaneous melanoma. However, structured training on skin cancer diagnosis and management is often lacking.
Italian Melanoma Intergroup
doaj +1 more source
Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad +12 more
wiley +1 more source
Immunosurveillance and Melanoma
There is considerable indirect and some direct evidence that immune mechanisms can play an important role in controlling the growth of melanoma. In mice, melanoma can be prevented with vaccines. Consequently, even though naturally occurring immunosurveillance may not be sufficiently potent to prevent melanoma, it is possible that the prophylactic ...
openaire +2 more sources
Cardiac thrombi mistaken for metastasis in recurrent melanoma
Intra-cardiac thrombi can be incidentally found in recurrent melanoma and need careful assessment. An 81-year-old woman, with a history of malignant nasopharyngeal melanoma, was evaluated by echocardiography and cardiac magnetic resonance due to the ...
Crea, Filippo +4 more
core +1 more source

