Results 141 to 150 of about 552,068 (289)

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

Advanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao, Qingqing Zhou, Mengli Li, Wen Zou, Zhenzhong Zhang, Jinjin Shi, Junjie Liu   +6 more
wiley   +1 more source

RAS/MEK/PI3K pathway inhibition augments response to CD40 agonism by targeting CD11b⁺ Bregs thereby overcoming melanoma PD1-resistance. [PDF]

Nat Commun
Yan C, Luo W, Yang J, Yang J, Chen SC, Bergdorf K, Hu Q, Weiss VL, Johnson DB, Liu Q, Richmond A.   +10 more
europepmc   +1 more source

Malignant Melanoma [PDF]

Acta Radiologica, 1955
B, JORGSHOLM, I, ENGDAHL
openaire   +2 more sources

ACSL5 Regulates Glucose Metabolism and Chemotherapy Sensitivity in Colorectal Cancer Cells under Glutamine Deficiency

Advanced Science, EarlyView.
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian, Qiaoxia Zhang, Xuedan Sun, Rick Francis Thorne, Zeyuan Shi, Qiang Ji, Zhangran Sun, Yuanxiang Lu, Qun Zhao, Xianjun Yu, Wanglai Hu, Mian Wu   +11 more
wiley   +1 more source

Genetic Evolution of Melanoma: Comparative Analysis of Candidate Gene Mutations in Healthy Skin, Nevi, and Tumors from the Same Patients. [PDF]

Int J Mol Sci
Gil-Barrachina M, Hernando B, Perez-Pastor G, Alegre-de-Miquel V, Valenzuela-Oñate C, Minguez-Lujan S, Monfort-Lanzas P, Tomas-Bort E, Marques-Torrejon MA, Martinez-Cadenas C.   +9 more
europepmc   +1 more source

Epidemiology of uveal melanomas in Moscow

, 2017
Е. Е. Гришина, M. Yu. Lerner, Э Г Гемджян   +2 more
openalex   +2 more sources

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

A protocol for development of a microsimulation model platform to evaluate the potential benefits, harms, and cost-effectiveness of risk-tailored melanoma screening. [PDF]

PLoS One
McLoughlin KG, Watts CG, Wade S, Smit AK, Soyer HP, Fernandez-Peñas P, Whiteman DC, Guitera P, Reyes-Marcelino G, Canfell K, Cust AE, Caruana M.   +11 more
europepmc   +1 more source

A Glimpse on Melanoma - Risk Factors and Treatment

, 2011
D Soumya
openalex   +1 more source

A melanoma subtype: Uveal melanoma [PDF]

Journal of the American Academy of Dermatology, 2011
Julia, Wu, Georg, Brunner, Julide Tok, Celebi   +2 more
openaire   +2 more sources