Frontiers in Genetics, 2013 Genomic variation is a trend observed in various human diseases including cancer. Genetic studies have set out to understand how and why these variations result in cancer, why some populations are pre-disposed to the disease, and also how genetics affect drug responses. The melanoma incidence has been increasing at an alarming rate worldwide.
Janet Wangari-Talbot, Suzie Chen
openaire +4 more sources
Dermoscopic characteristics of nodular squamous cell carcinoma and keratoacanthoma
Dermatology Practical & Conceptual, 2014 Background: Nodular squamous cell carcinoma (SCC) and keratoacanthoma (KA) may mimic a variety of other benign and malignant non-pigmented nodules. Objectives: To analyze the dermoscopic characteristics of nodular SCC and KA.
Matthew J. Lin, Yan Pan, John W. Kelly
doaj +1 more source
Immunotherapy in Acral and Mucosal Melanoma: Current Status and Future Directions
Frontiers in Immunology, 2021 Acral and mucosal melanomas are extremely rare in Caucasians; however, they are the predominant melanoma subtypes in Asians and other non-Caucasian populations.
Lili Mao +4 more
doaj +1 more source
Generative Adversarial Network for Personalized Art Therapy in Melanoma Disease Management [PDF]
arXiv, 2023 Melanoma is the most lethal type of skin cancer. Patients are vulnerable to mental health illnesses which can reduce the effectiveness of the cancer treatment and the patients adherence to drug plans. It is crucial to preserve the mental health of patients while they are receiving treatment.
arxiv
Transplantable melanomas in hamsters and gerbils as models for human melanoma : sensitization in melanoma radiotherapy : from animal models to clinical trials [PDF]
, 2018 The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption
Andrzej Słominski +11 more
core +1 more source
Dibutyltin(IV) and Tributyltin(IV) Derivatives of meso-Tetra(4-sulfonatophenyl)porphine Inhibit the Growth and the Migration of Human Melanoma Cells [PDF]
, 2019 Melanoma is the most aggressive and deadly form of skin cancer, which is largely due to its propensity to metastasize. Therefore, with the aim to inhibit the growth and the metastatic dissemination of melanoma cells and to provide a novel treatment ...
Caterina Di Sano +5 more
core +3 more sources
Antitumour activity of pembrolizumab in advanced mucosal melanoma: a post-hoc analysis of KEYNOTE-001, 002, 006. [PDF]
, 2018 BackgroundMucosal melanoma is an aggressive melanoma with poor prognosis. We assessed efficacy of pembrolizumab in patients with advanced mucosal melanoma in KEYNOTE-001 (NCT01295827), -002 (NCT01704287), and -006 (NCT01866319).MethodsPatients received ...
Arance, Ana S +14 more
core +1 more source
XXX Italian Melanoma Intergroup National Congress | 27-29 September 2024, Rimini, Italy
Dermatology Reportss from the Italian Melanoma Intergroup (IMI) XXX National ...
Italian Melanoma Intergroup (IMI)
doaj +1 more source
Trials, 2019 Background The WBRTMel trial is a multinational, open-label, phase III randomised controlled trial comparing whole brain radiotherapy (WBRT) to observation following local treatment of one to three melanoma brain metastases with surgery and/or ...
Serigne N. Lo +18 more
doaj +1 more source
Harnessing autophagy to overcome mitogen‐activated protein kinase kinase inhibitor‐induced resistance in metastatic melanoma [PDF]
, 2019 Background Patients with malignant melanoma often relapse after treatment with BRAF and/or mitogen‐activated protein kinase kinase (MEK) inhibitors (MEKi) owing to development of drug resistance.
Alexander, M. +6 more
core +1 more source