Results 141 to 150 of about 118,918 (292)

LIN28A blocks the EndMT process of high glucose‐induced HRMECs by stabilizing SIRT6 mRNA

Journal of Diabetes Investigation, EarlyView.
LIN28A promotes mRNA stability of SIRT6 to activate the AMPK signaling, thereby inhibiting the EndMT process induced by HG in HRMECs. ABSTRACT Background Diabetic retinopathy (DR) is a microvascular condition resulting from microangiopathy, causing gradual retinal damage and potential blindness.
Xueying Wang, Zixu Huang, Xiaohui Kuang, Yali Nan, Zhiwen Zhang, Zongming Song   +5 more
wiley   +1 more source

Reducing Medication‐Related Harm Through Home‐Based Primary Care

Journal of the American Geriatrics Society, EarlyView.
This figure illustrates teaching strategies for the five domains of geriatric care, represented as the “5 M's”: Medication, Mentation, Mobility, Multi‐Complexity, and Matters Most. For each domain, Ms. T's clinical problems are listed with corresponding interventions.
Thomas J. Haferkamp, Nora Spadoni, Lauren J. Gleason   +2 more
wiley   +1 more source

Synergistic interactions of melatonin and glucocorticoids in alleviating allergic airway inflammation. [PDF]

Front Med (Lausanne)
Zhang Z, Wang J, Ma T, Zhang X, Chen G, Wang B.   +5 more
europepmc   +1 more source

Salt glands in exo‐recretohalophytes: Development, physiological functions, and prospects for improving crop salt tolerance

Journal of Integrative Plant Biology, EarlyView.
This review examines salt glands in exo‐recretohalophytes, in which epidermal stem cells differentiate into unicellular, bicellular, or multicellular salt glands. Salt ions are transported to the leaves via the transpiration stream and enter salt glands through symplastic and apoplastic pathways. Finally, salt glands actively secrete salt ions from the
Limin Wang, Junyan Xie, Yiping Zou, Chunliang Yao, Hai Fan, Chenqi Shen, Wenyan Zhou, Jingran Qin, Xinke Zhang, Baoshan Wang, Jian Zhang, Guoliang Han   +11 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Time-of-Day Impacts Uterine Circadian Rhythms and Response to Oxytocin: Comparison of Uterine Function in Melatonin-Deficient C57BL/6 Versus Melatonin Proficient CBA/B6 Hybrid Mice. [PDF]

J Pineal Res
Duong TV, Yaw AM, Hoffmann HM.
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Melatonin's oncostatic effects in experimental breast cancer: A systematic review of dose-response and apoptotic mechanisms in animal models. [PDF]

Clinics (Sao Paulo)
Alves MS, Damous LL, Ferreira IDS, Ferreira CDS, Sorpreso ICE, Cipolla-Neto J, Baracat EC, Soares JM.   +7 more
europepmc   +1 more source

Headache‐associated photophobia is more prevalent during winter: A cross‐sectional study from a pediatric headache registry

Headache: The Journal of Head and Face Pain, EarlyView.
Carlyn Patterson Gentile, Geoffrey K. Aguirre, Andrew D. Hershey, Christina L. Szperka   +3 more
wiley   +1 more source

The Ecology of Human Sleep (EcoSleep) Cohort Study: Protocol for a longitudinal repeated measurement burst design study to assess the relationship between sleep determinants and outcomes under real‐world conditions across time of year

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary The interplay of daily life factors, including mood, physical activity, or light exposure, influences sleep architecture and quality. Laboratory‐based studies often isolate these determinants to establish causality, thereby sacrificing ecological validity.
Anna M. Biller, Nayab Fatima, Chrysanth Hamberger, Laura Hainke, Verena Plankl, Amna Nadeem, Achim Kramer, Martin Hecht, Manuel Spitschan   +8 more
wiley   +1 more source