Results 141 to 150 of about 242,415 (401)
Genetic disruption of the core circadian clock impairs hippocampus-dependent memory [PDF]
, 2014 Perturbing the circadian system by electrolytically lesioning the suprachiasmatic nucleus (SCN) or varying the environmental light:dark schedule impairs memory, suggesting that memory depends on the circadian system.
Chen, Xuanmao +4 more
core +2 more sources
Epilepsia Open, EarlyView.Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira +5 more
wiley +1 more source
Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions
Molecules, 2018 Melatonin, along with its metabolites, have long been known to significantly reduce the oxidative stress burden of aging cells or cells exposed to toxins. Oxidative damage is a result of free radicals produced in cells, especially in mitochondria.
R. Reiter +5 more
semanticscholar +1 more source
Frontiers in EndocrinologyBackgroundMelatonin is a key hormone in regulation of circadian rhythms, and involved in many rhythmic functions, such as feeding and locomotor activity. Melatonin reportedly counteracts stress responses in many vertebrates, including fish.
Clara Azpeleta +5 more
doaj +1 more source
Ketogenic diet for infantile epileptic spasms
Epilepsia Open, EarlyView.Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury +3 more
wiley +1 more source
BMC Plant Biology, 2019 Melatonin is a pleiotropic signaling molecule that plays multifarious roles in plants stress tolerance. The polyamine (PAs) metabolic pathway has been suggested to eliminate the effects of environmental stresses.
M. S. Jahan +7 more
semanticscholar +1 more source
The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination [PDF]
, 2016 Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The protective effects of melatonin (MLT) on various neurodegenerative diseases, including MS, have been suggested.
Ghadiri, T. +6 more
core
, 2021 Studies have shown that the use of the synthetic hormone melatonin is safe. A significant harm/benefit ratio in favor of the benefit is revealed. The use of the drug is recommended for manifestations of insomnia, such as difficulty falling asleep or periodic night awakenings, as well as to prevent Jetlag syndrome when changing time zones.
openaire +1 more source
Safe and Truly Ecofriendly LED Lighting
Energy Science &Engineering, EarlyView.ABSTRACT Truly ecofriendly and safe light‐emitting diode (LED) lighting in the built and urban environments requires the use of LED lights emitting significantly lower amount of blue light than conventional, first‐generation white LED lights. Thanks to substantial technology progress in the design and manufacturing of LEDs, this is now possible at the ...
Mario Pagliaro
wiley +1 more source
The role of melatonin in diabetes: therapeutic implications
Archives of Endocrinology and Metabolism, 2015 Melatonin referred as the hormone of darkness is mainly secreted by pineal gland, its levels being elevated during night and low during the day. The effects of melatonin on insulin secretion are mediated through the melatonin receptors (MT1 and MT2).
Shweta Sharma +4 more
doaj +1 more source