Results 151 to 160 of about 227,315 (399)
Circadian clocks and breast cancer [PDF]
, 2016 Circadian clocks respond to environmental time cues to coordinate 24-hour oscillations in almost every tissue of the body. In the breast, circadian clocks regulate the rhythmic expression of numerous genes.
Blakeman, V +3 more
core +2 more sources
MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective.
Annual Review of Pharmacology and Toxicology, 2016 Melatonin, or 5-methoxy-N-acetyltryptamine, is synthesized and released by the pineal gland and locally in the retina following a circadian rhythm, with low levels during the day and elevated levels at night.
Jiabei Liu +5 more
semanticscholar +1 more source
Dual sources of melatonin and evidence for different primary functions
Frontiers in EndocrinologyThis article discusses data showing that mammals, including humans, have two sources of melatonin that exhibit different functions. The best-known source of melatonin, herein referred to as Source #1, is the pineal gland.
Russel J. Reiter +8 more
doaj +1 more source
Evaluation of the EVA Descriptor for QSAR Studies: 3. The use of a Genetic Algorithm to Search for Models with Enhanced Predictive Properties (EVA_GA) [PDF]
, 2000 The EVA structural descriptor, based upon calculated fundamental molecular vibrational frequencies, has proved to be an effective descriptor for both QSAR and database similarity calculations.
Turner, D.B., Willett, P.
core +1 more source
Design Principles of Nanosensors for Multiplex Detection of Contaminants in Food
Small, EarlyView.This review discusses recent advancements in nanoparticle‐based nanosensors for multiplex detection of food contaminants, focusing on toxins and pathogens. It highlights the design principles, sensitivity, and selectivity of these sensors, offering insights into their practical applications for food safety monitoring and inspiring future innovations ...
Yang Zhang +10 more
wiley +1 more source
, 2001 Melatonin yaklaşık 50 yıl önce keşfedilmiş olup ve son yıllarda önemi daha çok anlaşılmış pineal bezden salınan bir hormondur. Vücut sıvılarındaki düzeyi gece maksimum düzeyde artarken, gündüz düşer. Yüksek diffüzyon yeteneği ve lipofilik yapısından dolayı mükemmel bir antioksidan olup, bilinen diğer antioksidanlardan daha güçlüdür.
Namıduru, E. Sibel +2 more
openaire +2 more sources
Macromolecular crystallography and biology at the Linac Coherent Light Source
Journal of Synchrotron Radiation, EarlyView.The significant advancements in biological research enabled by the Linac Coherent Light Source (LCLS) are explored. By offering ultra‐bright, coherent X‐ray pulses with femtosecond durations, LCLS has revolutionized the study of biological molecules and their dynamic processes. Techniques such as serial femtosecond crystallography leverage these unique
Sandra Mous +4 more
wiley +1 more source
Journal of Sleep Research, EarlyView., 2023 Summary Sleep disturbances and circadian disruption play a central role in adverse health, safety, and performance outcomes in shift workers. While biomathematical models of sleep and alertness can be used to personalise interventions for shift workers, their practical implementation is undertested. This study tested the feasibility of implementing two
Prerna Varma +6 more
wiley +1 more source
Melatonin decreases excessive polyspermy for single oocyte in pigs through the MT2 receptor
Scientific ReportsMelatonin supplementation during in vitro maturation (IVM) improves porcine oocyte maturation and embryonic development by exerting antioxidative effects.
Jing-Tao Sun +10 more
doaj +1 more source
Frontiers in Plant Science, 2016 Melatonin (N-acetyl-5-methoxytryptamine) plays important roles in regulating both biotic and abiotic stress tolerance, biological rhythms, plant growth and development.
Qiannan Wang +6 more
doaj +1 more source