Results 291 to 300 of about 181,700 (339)

Linking autism risk genes to morphological and pharmaceutical screening by high‐content imaging: Future directions and opinion

Psychiatry and Clinical Neurosciences, EarlyView.
Next‐generation sequencing has identified risk genes with large effect sizes for autism spectrum disorders (ASD). Although functional analysis of individual risk genes has progressed, the overall picture of ASD pathogenesis is unclear. Therefore, there is a need for morphological profiling of variants in these genes to fully comprehend their ...
Reza K. Arta, Yuichiro Watanabe, Jun Egawa, Vance P. Lemmon, Toshiyuki Someya   +4 more
wiley   +1 more source

Exogenous melatonin enhances drought tolerance and germination in common buckwheat seeds through the coordinated effects of antioxidant and osmotic regulation. [PDF]

BMC Plant Biol
Tian Z, He J, Wang Z, Zhang Z, Quinet M, Meng Y.   +5 more
europepmc   +1 more source

Grape constituents for protection against photodamage to skin

Photochemistry and Photobiology, EarlyView.
Excessive exposure to solar ultraviolet radiation has a major negative impact on the health of skin. It causes sunburn, photoaging, keratinocyte carcinomas, and melanomas. Current methods of prevention have failed to stem the incidence of these adverse effects. Grapes are natural products that are being investigated as preventive agents that can impede
Yuri Kwon, Rubina Shafi, Allen Oak, Mohammad Athar, Andrzej Slominski, Craig A. Elmets   +5 more
wiley   +1 more source

Targeted disruption of the aralkylamine <i>N</i>-acetyltransferase gene in a seasonal mammal, <i>Mesocricetus auratus</i>. [PDF]

PNAS Nexus
Kawabe J, Kawakami N, Hirose M, Kitamura Y, Nagano M, Maruyama Y, Matsuyama Y, Hamano T, Koinuma S, Shiina T, Kobayashi M, Matsumura R, Hattori A, Shigeyoshi Y, Ogura A, Node K, Akashi M.   +16 more
europepmc   +1 more source

Pharmaceutical Neuroenhancement in the Quest for Worth at Work

Sociological Inquiry, EarlyView.
This article examines the use of psychoactive substances for cognitive enhancement in the context of work. By drawing upon existing qualitative research and sociological theories on meaningful work, valuation, and human agency, I explore cultural and institutional processes encouraging individuals to engage in such practices and argue that ...
Sigita Doblytė
wiley   +1 more source

Positive interaction between melatonin and methyl jasmonate enhances <i>Fusarium</i> wilt resistance in <i>Citrullus lanatus</i>. [PDF]

Front Plant Sci
Yan J, Zhao T, Chen Y, Liu H, Wei C, Ma J, Zhang Y, Yang J, Zhang X, Li H.   +9 more
europepmc   +1 more source

Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut–athlete on Mars exploration missions

Experimental Physiology, EarlyView.
Abstract Long‐duration spaceflight impacts essentially every system in the human body, resulting in multisystem deconditioning that might impair the health and performance of crewmembers, particularly on long‐duration exploration missions to Mars. In this review, we apply the sport science model of athlete monitoring, testing and training to astronauts;
Luke DeVirgiliis, Nicholas J. Goode, Kurt W. McDowell, Kirk L. English, Robert Novo, Virina Botros, Ginika Agwu, Jessica M. Scott, Lori L. Ploutz‐Snyder   +8 more
wiley   +1 more source

Impact of long‐haul airline travel on athletic performance and recovery: A critical review of the literature

Experimental Physiology, EarlyView.
Abstract Participation in many important sport events (e.g., World championships, Olympics) requires athletes to fly >4 h and to cross several time zones. This transmeridian travel results in a transient desynchronization of the body's circadian rhythms due to a disconnect between the timing of the endogenous circadian oscillator and the external ...
Petros G. Botonis, Argyris G. Toubekis, David W. Hill, Toby Mündel   +3 more
wiley   +1 more source

Melatonin Secretion and Impacts of Training and Match Schedules on Sleep Quality, Recovery, and Circadian Rhythms in Young Professional Football Players. [PDF]

Biomolecules
Almendros-Ruiz A, Conde-Pipó J, Aranda-Martínez P, Olivares-Jabalera J, Acuña-Castroviejo D, Requena B, Fernández-Martínez J, Mariscal-Arcas M.   +7 more
europepmc   +1 more source

The impact of long‐haul travel and 13 h time change on sleep and rest activity circadian rhythm in speed skaters during World Cup competitions

Experimental Physiology, EarlyView.
Abstract Athletes frequently compete only a few days after long‐haul travel. Longitudinal real‐world data on athletes’ sleep and sleep–wake cycle in competitive settings remain scarce. This study assessed the impact of a long‐haul travel across ∼13 time zones on sleep patterns, rest–activity circadian rhythms (RAR), and their subsequent effects on ...
Giorgio Varesco, Chun William Yao, Evelyne Dubé, Guido Simonelli, François Bieuzen   +4 more
wiley   +1 more source