Results 121 to 130 of about 61,717 (309)

Melatonin regulates circadian clock proteins expression in allergic airway inflammation

Heliyon
Asthma demonstrates a strong circadian rhythm with disrupted molecular clock. Melatonin which can directly regulate circadian rhythm has been reported to alleviate asthma, but whether this effect is related to its regulation on circadian clock has not ...
Si-Nuo Guo, Xu-Qin Jiang, Ning Chen, Si-Ming Song, Yu Fang, Qiu-Meng Xie, Guang-He Fei, Hui-Mei Wu   +7 more
doaj   +1 more source

Research on sleep quality and influencing factors among medical staff in a tertiary hospital in Anhui Province, China

Sleep Research, EarlyView.
To assess sleep quality and identify key influencing factors among medical staff in a tertiary hospital to support health policy development. Conducted in July 2024 using validated scales: Pittsburgh Sleep Quality Index (PSQI); Depression, Anxiety, and Stress Scale‐21; and Assessed: sleep quality, latency, disturbances, and daytime dysfunction.
Xiao‐Ying Jin, Ting Jiang, Ri‐Hong Wei, Meng‐Dan Chu, Han Li, Shan Zhang, Zeng‐Feng Su   +6 more
wiley   +1 more source

Scientific Basis for the Potential Use of Melatonin in Bone Diseases: Osteoporosis and Adolescent Idiopathic Scoliosis

Journal of Osteoporosis, 2010
The objective of this paper was to analyze the data supporting the possible role of melatonin on bone metabolism and its repercussion in the etiology and treatment of bone pathologies such as the osteoporosis and the adolescent idiopathic scoliosis (AIS).
E. J. Sánchez-Barceló, M. D. Mediavilla, D. X. Tan, R. J. Reiter   +3 more
doaj   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Melatonin Alleviates BPA-Induced Testicular Apoptosis and Endoplasmic Reticulum Stress

Frontiers in Bioscience-Landmark
Background: The impact of melatonin on bisphenol A (BPA)-induced testicular apoptosis and endoplasmic reticulum (ER) stress was explored. Methods: The mice received BPA (50 mg/kg) by gavage for 30 days while being injected with 20 mg/kg melatonin ...
Qi Qi, Lei Feng, Jingjing Liu, Da Xu, Guoqing Wang, Xiaoyan Pan   +5 more
doaj   +1 more source

Dynamics of the melatonin MT1 receptor in the rat parotid gland upon melatonin administration [PDF]

, 2016
Our recent ultrastructural study of human parotid glands revealed that the melatonin receptors, MT1 and MT2, are localised in the plasma cell membranes of acinar and ductal cells but also, and intriguingly, predominantly in acinar secretory granules ...
Ekstrom, J, ISOLA, MICHELA, ISOLA, RAFFAELLA, LILLIU, MARIA ALBERTA, LOY, FRANCESCO   +4 more
core  

Metabolic engineering of adipose‐derived stem cell exosomes via arachidonic acid potentiates diabetic wound repair by orchestrating angiogenesis: A multi‐omics guided strategy

VIEW, EarlyView.
AA‐Exos promotes angiogenesis and accelerates diabetic wound healing by activating the PI3K/AKT/mTOR pathway. Abstract Diabetic wounds are common and challenging complications of diabetes, characterized by delayed healing and an increased risk of infection.
Yujiao Cai, Jinnan Wang, Yan Liu, Xiaoke Zhu, Zhanyuan Yuan, Weiling Li, Dehui Che, Dongsheng Cao   +7 more
wiley   +1 more source

Research on the effects and related mechanisms of geomagnetic storm on depression

Brain Research Bulletin
Objective: Depression has become disabling disease in the world. Geomagnetic storm is closely related to depression behavior, and melatonin is an important factor in the pathogenesis of depression. This study observed the effects of different intensities
Hui Wu, Yuan Yang, Weiyu Chang, Xinli Chen, Shiqi Yang, Min Xu, Keyu Liu, Yu Yun, Liang Dong   +8 more
doaj   +1 more source

Polymorphism of the MTNR1A Melatonin Receptor Gene in Goat Breeds of Northern Italy. [PDF]

Animals (Basel), 2023
Agradi S, Luridiana S, Mura MC, Cosso G, Vigo D, Menchetti L, Brecchia G, Carcangiu V, Curone G.   +8 more
europepmc   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source