Results 111 to 120 of about 25,767 (309)

Quantum mechanics insights into melatonin and analogs binding to melatonin MT1 and MT2 receptors

Scientific Reports
Melatonin receptors MT1 and MT2 are G protein-coupled receptors that mediate the effects of melatonin, a hormone involved in circadian rhythms and other physiological functions.
Gabriela de Lima Menezes, Katyanna Sales Bezerra, Jonas Ivan Nobre Oliveira, John Fontenele Araújo, Douglas Soares Galvão, Roosevelt Alves da Silva, Marielena Vogel Saivish, Umberto Laino Fulco   +7 more
doaj   +1 more source

Membrane Melatonin Receptors Activated Cell Signaling in Physiology and Disease. [PDF]

Int J Mol Sci, 2021
Nikolaev G, Robeva R, Konakchieva R.
europepmc   +1 more source

Postoperative Sleep Interventions and Cardiac Surgery: A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Sleep disturbance is a common issue affecting nearly 78% of cardiothoracic postoperative patients. There are no systematic reviews of randomised controlled trials (RCTs) that evaluate the impact of sleep interventions within this population.
Alexander Lombardo, James Tsimiklis, Ammar Zaka, Alasdair Leslie, Brandon Stretton, Joshua Kovoor, Pramesh Kovoor, Stephen Bacchi, Aashray Gupta   +8 more
wiley   +1 more source

Associative administration of cimetidine and exogenous melatonin on the endometrial receptors of estrogen, collagen and hormone levels in adult rats [PDF]

, 2020
Sandra Maria Souza da Silva, Laíse de Souza Elias, Romildo Luciano da Silva, Paloma Lys de Medeiros, Jeymesson Raphael Cardoso Vieira, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley Teixeira   +6 more
openalex   +1 more source

Melatonin receptor structure and signaling

Journal of Pineal Research
AbstractMelatonin (5‐methoxy‐N‐acetyltryptamine) binds with high affinity and specificity to membrane receptors. Several receptor subtypes exist in different species, of which the mammalian MT1 and MT2 receptors are the best‐characterized. They are members of the G protein‐coupled receptor superfamily, preferentially coupling to Gi/o proteins but also ...
Okamoto, Hiroyuki, Cecon, Erika, Nureki, Osamu, Rivara, Silvia, Jockers, Ralf   +4 more
openaire   +4 more sources

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Melatonin attenuates acute and chronic itch in mice: the antioxidant and anti-inflammatory effects of melatonin receptors. [PDF]

Ann Transl Med, 2022
Zhang L, Zhang JT, Huang Y, Zhou GK, Zhou Y, Yang JP, Liu T.   +6 more
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Bos taurus and Cervus elaphus as Non-Seasonal/Seasonal Models for the Role of Melatonin Receptors in the Spermatozoon. [PDF]

Int J Mol Sci, 2022
Fernández-Alegre E, Lacalle E, Soriano-Úbeda C, González-Montaña JR, Domínguez JC, Casao A, Martínez-Pastor F.   +6 more
europepmc   +1 more source

Structural basis of ligand recognition at the human MT1 melatonin receptor

, 2020
B. Stauch, L.C. Johansson, J.D. McCorvy, N. Patel, Guangzeng Han, X.-P. Huang, C. Gati, A. Batyuk, S.T. Slocum, A. Ishchenko, W. Brehm, T.A. White, N. Michaelian, C. Madsen, L. Zhu, T.D. Grant, J.M. Grandner, A. Shiriaeva, R.H.J. Olsen, A.R. Tribo, S. Yous, R.C. Stevens, U. Weierstall, V. Katritch, B.L. Roth, W. Liu, V. Cherezov   +26 more
openalex   +1 more source