Results 31 to 40 of about 2,729,675 (338)
Monoaminergic Neuropathology in Alzheimer's disease [PDF]
, 2016 Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira +11 more
core +1 more source
Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]
, 2020 Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core +1 more source
Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus). [PDF]
PLoS ONE, 2018 Melatonin is a neurohormone produced in both animals and plants. It binds at least three G-protein-coupled receptors: MT1 and MT2, and Mel1cGPR. Mammalian GPR50 evolved from the reptilian/avian Mel1c and lost its capacity to bind melatonin in all the ...
Célia Gautier +8 more
doaj +1 more source
Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology [PDF]
, 2013 Cholangiocytes are epithelial cells lining the biliary epithelium. Cholangiocytes play several key roles in the modification of ductal bile and are also the target cells in chronic cholestatic liver diseases (i.e., cholangiopathies) such as PSC, PBC ...
Alvaro, Domenico +6 more
core +1 more source
Melatonin antagonizes lipopolysaccharide-induced pulpal fibroblast responses
BMC Oral Health, 2020 Background Pulpal inflammation is known to be mediated by multiple signaling pathways. However, whether melatonin plays regulatory roles in pulpal inflammation remains unclear.
Nutthapong Kantrong +2 more
doaj +1 more source
Journal of Pineal Research, 2019 The hormone melatonin connects environmental cues, such as photoperiod and temperature, with a number of physiological and behavioural processes, including seasonal reproduction, through binding to their cognate receptors.
Elia Ciani +6 more
semanticscholar +1 more source
Melatonin, Melatonin Receptors and Melanophores: A Moving Story [PDF]
Pigment Cell Research, 2004 Melatonin (5‐methoxy N‐acetyltryptamine) is a hormone synthesized and released from the pineal gland at night, which acts on specific high affinity G‐protein coupled receptors to regulate various aspects of physiology and behaviour, including circadian and seasonal responses, and some retinal, cardiovascular and immunological functions.
Sugden, D +3 more
openaire +2 more sources
Melatonin signaling modulates clock genes expression in the mouse retina. [PDF]
PLoS ONE, 2014 Previous studies have shown that retinal melatonin plays an important role in the regulation of retinal daily and circadian rhythms. Melatonin exerts its influence by binding to G-protein coupled receptors named melatonin receptor type 1 and type 2 and ...
Susumu Hiragaki +5 more
doaj +1 more source
Melatonin-related dysfunction in chronic restraint stress triggers sleep disorders in mice
Frontiers in Pharmacology, 2023 Stress may trigger sleep disorders and are also risk factors for depression. The study explored the melatonin-related mechanisms of stress-associated sleep disorders on a mouse model of chronic stress by exploring the alteration in sleep architecture ...
Tian-Ji Xia +12 more
doaj +1 more source
Journal of Advanced Research, 2022 Introduction: The human genome encodes two melatonin receptors (MT1 and MT2) that relay melatonin signals to cellular interior. Accumulating evidence has linked melatonin to multiple health benefits, among which its anticancer effects have become well ...
Qianhui Sun +15 more
doaj +1 more source