Results 11 to 20 of about 2,729,675 (338)

Human gastroenteropancreatic expression of melatonin and its receptors MT1 and MT2. [PDF]

PLoS ONE, 2015
The largest source of melatonin, according to animal studies, is the gastrointestinal (GI) tract but this is not yet thoroughly characterized in humans.
Fanny Söderquist, Per M Hellström, Janet L Cunningham   +2 more
doaj   +2 more sources

Melatonin receptors: molecular pharmacology and signalling in the context of system bias. [PDF]

Br J Pharmacol, 2018
Cecon E, Oishi A, Jockers R.
europepmc   +2 more sources

Melatonin receptor structure and signaling

Journal of Pineal Research
Melatonin (5‐methoxy‐N‐acetyltryptamine) binds with high affinity and specificity to membrane receptors. Several receptor subtypes exist in different species, of which the mammalian MT1 and MT2 receptors are the best‐characterized.
H. Okamoto, E. Cecon, Osamu Nureki, S. Rivara, Ralf Jockers   +4 more
semanticscholar   +5 more sources

Epigenetic regulation of melatonin receptors in neuropsychiatric disorders. [PDF]

Br J Pharmacol, 2018
Bahna SG, Niles LP.
europepmc   +2 more sources

Carbamate Insecticides Target Human Melatonin Receptors. [PDF]

Chem Res Toxicol, 2017
Popovska-Gorevski M, Dubocovich ML, Rajnarayanan RV.   +2 more
europepmc   +2 more sources

Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views

Journal of Pineal Research
ABSTRACTSleep, constituting approximately one‐third of the human lifespan, is a crucial physiological process essential for physical and mental well‐being. Normal sleep consists of an orderly progression through wakefulness, non‐rapid eye movement (NREM) sleep, and rapid eye movement (REM) sleep, all of which are tightly regulated.
Stefano Comai, Gabriella Gobbi
openaire   +4 more sources

Role of melatonin receptors in the effect of estrogen on brain edema, intracranial pressure and expression of aquaporin 4 after traumatic brain injury [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Traumatic brain injury (TBI) is one of the most common causes of death and disability in modern societies. The role of steroids and melatonin is recognized as a neuroprotective factor in traumatic injuries.
Nader Shahrokhi, Mohammad khaksari, Gholamreza Asadikaram, Zahra soltani, Nava Shahrokhi   +4 more
doaj   +1 more source

Melatonin in Th17/Treg differentiation: the contribution of the hormone's own production by T lymphocytes

Медицинская иммунология, 2023
The hormone melatonin is involved in regulation of functioning of almost all organs and systems of the organism. In the immune system, T lymphocytes are an important target of melatonin: they express specific melatonin receptors with different affinities
N. S. Glebezdina, E. M. Kuklina, I. V. Nekrasova   +2 more
doaj   +1 more source

Melatonin and Its Homologs Induce Immune Responses via Receptors trP47363-trP13076 in Nicotiana benthamiana

Frontiers in Plant Science, 2021
Melatonin (N-acetyl-5-methoxytryptamine), a naturally occurring small molecule, can protect plants against abiotic stress after exogenous treatmenting with it.
Mengmeng Kong, Tao Sheng, Jing Liang, Qurban Ali, Qin Gu, Huijun Wu, Jian Chen, Jia Liu, Xuewen Gao   +8 more
doaj   +1 more source

Developmental effect of light deprivation on synaptic plasticity of rats' hippocampus: implications for melatonin [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): There are few reports have demonstrated the effect of a change-in-light experience on the structure and function of hippocampus. A change-in-light experience also affects the circadian pattern of melatonin secretion.
Sayyed Alireza Talaei, Abolfazl Azami, Mahmoud Salami   +2 more
doaj   +1 more source