Results 61 to 70 of about 25,767 (309)

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Growing Teeth in the Dark: Circadian Rhythmic Tooth Growth Regulated by Melatonin?

Dental Hypotheses, 2011
Introduction: Melatonin is re-leased from the pineal gland and its release is regulated by the light. It is a well-known hormone for circadian rhythm that affects various activities of our body.
Gang Shen, William Jia, Fang Ji, Jiang Tao   +3 more
doaj  

Agomelatine is superior to melatonin in pain suppression: An experimental study

Neurological Sciences and Neurophysiology, 2020
Objective: Agomelatine is a synthetic analog of melatonin with selective agonist action on melatonin MT1 and MT2 receptors and antagonistic effect on serotonin 5HT2c receptors. Similar to melatonin, it also has antinociceptive properties.
Ali Okan Yucel, Devrim Demir-Dora, Mehmet Ferit İsbir, Babür Dora   +3 more
doaj   +1 more source

Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population. [PDF]

PLoS ONE, 2010
Melatonin is a powerful antioxidant and a synchronizer of many physiological processes. Alteration of the melatonin pathway has been reported in circadian disorders, diabetes and autism spectrum disorders (ASD).
Pauline Chaste, Nathalie Clement, Oriane Mercati, Jean-Luc Guillaume, Richard Delorme, Hany Goubran Botros, Cécile Pagan, Samuel Périvier, Isabelle Scheid, Gudrun Nygren, Henrik Anckarsäter, Maria Rastam, Ola Ståhlberg, Carina Gillberg, Emilie Serrano, Nathalie Lemière, Jean Marie Launay, Marie Christine Mouren-Simeoni, Marion Leboyer, Christopher Gillberg, Ralf Jockers, Thomas Bourgeron   +21 more
doaj   +1 more source

1‐Methylcyclopropene Containing‐Paper Enhances the Storability of Anxi Persimmon by Regulating Energy Metabolism

Future Postharvest and Food, EarlyView.
1‐Methylcyclopropene (1‐MCP) containing‐paper delayed the color change and maintained higher rate of commercially acceptable fruit in Anxi persimmons during storage were attributed to the increased activities of H+‐ATPase, Ca2+‐ATPase, and Mg2+‐ATPase and higher levels of ATP content and energy charge (EC).
Lingzhen Zeng, Lili Shi, Yuzhao Lin, Yixiong Lin, Hetong Lin, Hui Wang   +5 more
wiley   +1 more source

A Comprehensive Review on Nutrition, Phytochemistry, Pharmacology and Food Application Perspectives of Bioactive Rich Superfruits

Future Postharvest and Food, EarlyView.
The review critically evaluated and compared the selected superfruit phytochemistry, their bioactive composition and the key health benefits majorly emphasizing the antioxidant potential. It has highlighted the translational challenges in formulating functional foods by addressing the issues related to delivery system, bioavailability mechanism and the
Sharath Kumar Nagaraja, Javid Iqbal Mir, Mahendra Kumar Verma, Aamir Hussain Dar   +3 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Endogenous and Exogenous Melatonin Exposure Attenuates Hepatic MT₁ Melatonin Receptor Protein Expression in Rat

Antioxidants, 2019
Melatonin receptors are highly relevant for the hepatoprotective effects of the pineal hormone melatonin after experimental hemorrhagic shock in rats. In this study, we sought to determine the spatial expression pattern and a putative regulation of two ...
Alexander M. Mathes, Paul Heymann, Christian Ruf, Ragnar Huhn, Jochen Hinkelbein, Thomas Volk, Tobias Fink   +6 more
doaj   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

Ibrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard, Vivian Kapio Abem, Sagor Kumar Roy   +2 more
wiley   +1 more source