Characteristics of the Fatty Acid Composition in Elderly Patients with Occupational Pathology from Organophosphate Exposure. [PDF]
Goncharov NV +9 more
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L-Carnitine and Mildronate Demonstrate Divergent Protective Effects on Mitochondrial DNA Quality Control and Inflammation Following Traumatic Brain Injury. [PDF]
Gureev AP +5 more
europepmc +1 more source
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Meldonium in Treatment of Patients With Myocardial Infarction
Kardiologiia, 2014Therapy with meldonium belongs to "metabolic direction" which is developing in cardiovascular medicine. Its purpose is restoration of impaired cellular metabolism.
G I, Nechaeva +2 more
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Testing Meldonium: Assessing Soviet pragmatic alternatives to the randomized controlled trial
Clinical Trials, 2021Background/aims Current research largely tends to ignore the drug-testing model that was developed in the “Second World” as an explicit alternative to the randomized controlled trial. This system can be described as “socialist pharmapolitics,” accounting for the specific features of state socialism that influenced the development and testing of ...
Anastasiya Chirkova +2 more
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Analytical methods for meldonium determination in urine samples
Analytical Letters, 2020Here is reported a rapid analytical method for meldonium and other beta blockers (metoprolol, amlodipine, bisoprolol, nebivolol, betaxolol, and carvediol) in urine samples using Fourier transform i...
L. D. Rusu +4 more
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Sixty seconds on . . . meldonium
BMJ, 2016Yes, definitely a double fault for the Russian tennis star. Meldonium (also known as mildronate) is a drug made in Latvia used for treating heart failure, angina, and myocardial infarction. It isn’t licensed in the United States or Europe. We don’t know, but it seems unlikely. She has said that she had magnesium …
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Urinary excretion studies of meldonium after multidose parenteral application
Journal of Pharmaceutical and Biomedical Analysis, 2018Meldonium is a drug exhibiting cardioprotective and anti-ischemic effects. Due to its potential performance-enhancing benefit in sports, meldonium was added to the World Anti-Doping Agency list of prohibited substances in 2016. Since then, a high number of adverse analytical findings reported on meldonium has questioned meldonium`s detection time in ...
Guro Forsdahl +6 more
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Chronic cerebrovascular diseases and neuroprotection: the clinical efficacy of meldonium (Mildronat)
Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2020To evaluate the efficacy of meldonium (mildronat) in patients with chronic cerebral vascular disease (CVD).An open comparative study of the clinical efficacy of meldonium (mildronat) in patients with chronic CVD caused by arterial hypertension and atherosclerosis was conducted.
M M, Tanashyan +5 more
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Optoelectronical method for identification of meldonium in urine samples
Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies IX, 2018Meldonium is an anti-ischemia drug developed in 1970 by Ivars Kalvins at the USSR Latvia Institute of organic synthesis. Meldonium is reportedly capable of providing clinical benefit for those suffering from heart conditions, such as low blood flow to the heart and angina, as well as neurodegenerative disorders and bronchopulmonary diseases. It appears
Georgeta Marcela Bican +4 more
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Efficiency of Meldonium in the Complex Therapy of Acute Coronary Syndrome
Kardiologiia, 2014We examined 140 patients (mean age 54.8±3.1 years) with ST elevation acute coronary syndrome resulting in Q-wave myocardial infarction of the left ventricle. From the first hours complex therapy of these patients comprised meldonium (1 g/day intravenously for 2 weeks then orally until 1.5 months).
V P, Mikhin +4 more
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