Results 111 to 120 of about 1,036 (190)

Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma. [PDF]

open access: yesPharmaceuticals (Basel), 2023
Minnelli C   +9 more
europepmc   +1 more source

Letter to Editor: Potential Use of Meldonium as Supportive Treatment in Lifestyle Diseases: Addressing Knowledge Gaps and the Need for Further Research [PDF]

open access: yes
Meldonium, a drug more familiar in the sports world than in clinical medicine, acts as a structural analog of gamma-butyrobetaine and influences carnitine metabolism by inhibiting gamma-butyrobetaine hydroxylase. This results in reduced carnitine levels,
Grzesiak, Magdalena, Szymański, Oskar
core   +1 more source

Phosphoglycerate kinase 1 as a therapeutic target in neurological disease [PDF]

open access: yes
Phosphoglycerate kinase 1 (PGK1) is a highly conserved enzyme that catalyzes the initial ATP-producing step in glycolysis. Improving cellular energy production by increasing PGK1 activity may be beneficial in multiple neurological conditions where cell ...
Chaytow, Helena   +3 more
core   +1 more source

Role of pFox inhibitors in the treatment of patients with acute myocardial ischemia

open access: yesТерапевтический архив, 2014
AIM: To evaluate the anti-ischemic and anti-anginal efficacy of meldonium (Idrinol) in its short-term use as part of combination therapy in patients with chronic heart failure in the early post-infarction period/MATERIAL AND METHODS: The investigation ...
M E Statsenko, S V Turkina, N N Shilina
doaj  

The Effects of a Meldonium Pre-Treatment on the Course of the LPS-Induced Sepsis in Rats. [PDF]

open access: yesInt J Mol Sci, 2022
Đurašević S   +12 more
europepmc   +1 more source

The unusual pharmacokinetics of meldonium: Implications for doping

open access: yesPharmacological Research, 2016
Edgars, Liepinsh, Maija, Dambrova
openaire   +2 more sources

Meldonium

open access: yesPractical Diabetes, 2016
openaire   +2 more sources

Meldonium as a supernosological drug

open access: yesConsilium Medicum, 2020
openaire   +1 more source

Myocardial metabolic changes under the influence of meldonium treatment

open access: yes, 2021
Background. Currently, there is a process of ldquo;rejuvenationrdquo; of the ICC, occupying important positions in society, which is why the given disease needs to be considered as one with important social value. Objective of the study. Randomized clinical trial analysis of the efficacy and harmlessness of inclusion in standardized pharmacotherapy of ...
openaire   +1 more source

Impact myocardial cytoprotection and inotropic stimulation at the annual prognosis in patients with myocardial infarction lifting segment ST, complicated heart failure

open access: yesКардиоСоматика, 2015
The article analyzes the effectiveness and safety of treatment cytoprotectant meldonium dihydrate and inotropic stimulator of levosimendan on an annual prognosis in patients with myocardial infarction complicated by acute heart failure II-III class ...
M. N Sinkova   +5 more
doaj  

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