Results 91 to 100 of about 1,036 (190)

Decrease in Long-Chain Acylcarnitine Tissue Content Determines the Duration of and Correlates with the Cardioprotective Effect of Methyl-GBB [PDF]

, 2017
Publisher Copyright: © 2017 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society)Ischaemia in the heart is accompanied by the accumulation of long-chain acylcarnitines (LCACs) which is one of the multiple factors that ...
Aguer, Dambrova, Diaz, Drosatos, Fillmore, Ford, Gorgens, Grigat, Grube, Idell-Wenger, Kilkenny, Korge, Koves, Kuka, Li, Liepinsh, Liepinsh, Liepinsh, Liepinsh, Liepinsh, Liepinsh, Liepinsh, Liepinsh, Liepinsh, Makrecka, McCoin, McGrath, Sauer, Stuart, Tretzel, Ussher, Vilskersts, Wessels, Zhang   +33 more
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Features of meldonium effect on the cells viability and mitochondria of blood leucocytes in patients with angina pectoris

Acta Biomedica Scientifica
Background. The ambiguous effectiveness of cardiocytoprotectors and the low level of evidence for their use in coronary heart disease (CHD) necessitate the study of their direct effect on cell viability for assessing cytoprotective activity.The aim.
A. L. Khokhlov, O. V. Romashchenko, S. V. Nadezhdin, P. K. Alferov, L. V. Statsenko   +4 more
doaj   +1 more source

Model framework for off label use of medicines [PDF]

, 2016
Background The drug licensing regulatory system ensures that marketed drugs to be used, meet the high standards and requirements for quality, efficacy and safety.
Glavas Dodov, Marija, Koshi, Blerina, Nica, Vasilka, Simonovska Crcarevska, Maja, Slaveska-Raicki, Renata, Zisovska, Elizabeta   +5 more
core  

Crystal structures of binary compounds of meldonium 3-(1,1,1-trimethylhydrazin-1-ium-2-yl)propanoate with sodium bromide and sodium iodide

Acta Crystallographica Section E: Crystallographic Communications, 2018
3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate (C6H14N2O2, M, more commonly known under its commercial names Meldonium or Mildronate) co-crystalizes with sodium bromide and sodium iodide forming polymeric hydrates poly[[tetra-μ-aqua-diaquabis[3-(1,1,1 ...
Alexander Y Nazarenko
doaj   +1 more source

Approach to detect possible genotoxic effects of metals in plants [PDF]

, 2016
During the intensive research in past decades, the scientific community and regulatory agencies also, focused their interest on measuring contaminant levels in tissues and environmental samples and on understanding the mechanisms of toxicity of different
Baceva, Katerina, Gjorgieva Ackova, Darinka, Kadifkova-Panovska, Tatjana, Stafilov, Trajče   +3 more
core  

Revista de ştiinţe ale sănătăţii din Moldova = Moldovan journal of health sciences. 2022, Vol. 29(3) [PDF]

, 2022
Revista de Științe ale Sănătății din Moldova (Moldovan Journal of Health Sciences) a fost lansată în octombrie 2014. Aceasta este editată în limbile română și engleză, conform standardelor și ghidurilor internaționale actuale în domeniul științelor ...

core  

Analysis of consumption of insulin in the municipality of Stip from 2011 to 2014 [PDF]

, 2016
Diabetes mellitus is a syndrome characterized by chronic hyperglycemia and disorder of the metabolism of carbohydrates, protein and fat associated with a relative or absolute lack of insulin secretion and insulin action.
Angelovska, Bistra, Atanasova, Dijana, Atanasova, Marija, Drakalska, Elena, Petrova, Aleksandra   +4 more
core   +1 more source

Preventive cytoprotection in social diseases

Терапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov, G N Gorokhovskaya, A M Shilov, V L Yun, M A Khamurzova   +4 more
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EFFECTIVENESS OF MELDONIUMIN IN CHRONIC HEART FAILURE PATIENTS

Медицинский совет, 2017
This article discusses the relevance of the high mortality of cardiovascular diseases (CVD) and their complications. Provides an overview of research conducted in the field of treatment of chronic heart failure and other cardiovascular diseases.
G. N. Gorokhovskaya, V. L. Yoon, A. S. Skotnikov, A. I. Martynov, E. Yu. Maychuk   +4 more
doaj   +1 more source

Chemoreactomic analysis of citrulline malate molecules

Неврология, нейропсихиатрия, психосоматика, 2017
Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin, O. A. Gromova, L. E. Fedotova, A. N. Gromov, K. V. Rudakov   +4 more
doaj   +1 more source