Results 71 to 80 of about 364 (156)

Post-COVID syndrome: status of carbohydrate metabolism in patients with hypertension and stable ischemic heart disease

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Post-COVID syndrome is associated with a wide range of chronic symptoms or conditions. Coronavirus di­sease 2019 (COVID-19) causes metabolic disorders such as hyperglycemia, insulin resistance.
O.V. Kuryata, O.S. Mytrokhina, Yu.S. Kushnir, O.I. Stadnyk   +3 more
doaj   +1 more source

Unsolved problems of cytoprotective therapy in patients with coronary heart disease

Терапевтический архив, 2015
The paper gives data on the proven efficiency of myocardial cytoprotection with the pFOX inhibitors trimetazidine and meldonium for coronary heart disease.
M E Statsenko, S V Turkina, A A Ermolenko   +2 more
doaj  

Use of meldonium in the combination treatment of patients with heart failure in the early post-infarction period

Терапевтический архив, 2014
AIM: To evaluate the impact of 10-14-day intravenous administration of meldonium as part of combination therapy in patients with chronic heart failure in the early post-infarction period on the recovery period, structural and functional parameters, and ...
M E Statsenko, N N Shilina, S V Turkina
doaj  

DETERMINATION OF MELDONIUM, γ-BUTYROBETAINE, AND CARNITINE IN BLOOD PLASMA BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH MASS-SELECTIVE DETECTION

Разработка и регистрация лекарственных средств, 2019
A procedure for simultaneous quantitative determination of meldonium, L-carnitine, and γ-butyrobetaine in blood plasma by high-performance liquid chromatography with mass-selective detection and the isotopically labeled d9L-carnitine as internal standard
P. N. Sorokoumov, E. I. Savelieva, G. V. Karakashev, V. A. Kopeikin, A. S. Radilov   +4 more
doaj  

Meldonium: dotychczasowe i nowe możliwości terapeutyczne

Postępy Biochemii
Meldonium functions as an inhibitor of γ-butyrobetaine hydroxylase, the enzyme responsible for catalyzing the biosynthesis of L-carnitine. By inhibiting mitochondrial β-oxidation of fatty acids under hypoxic conditions, meldonium exerts cytoprotective effects on cardiac, hepatic, and pulmonary tissues.
Halszka Ponamarczuk, Marcin Popielarski
openaire   +1 more source

Meldonium: current and emerging therapeutic applications

Postepy biochemii
Meldonium functions as an inhibitor of γ-butyrobetaine hydroxylase, the enzyme responsible for catalyzing the biosynthesis of L-carnitine. By inhibiting mitochondrial β-oxidation of fatty acids under hypoxic conditions, meldonium exerts cytoprotective effects on cardiac, hepatic, and pulmonary tissues.
Halszka, Ponamarczuk, Marcin, Popielarski   +1 more
openaire   +1 more source

The unusual pharmacokinetics of meldonium: Implications for doping

Pharmacological Research, 2016
Edgars, Liepinsh, Maija, Dambrova
openaire   +2 more sources

Meldonium Inhibits Cell Motility and Wound-Healing in Trabecular Meshwork Cells and Scleral Fibroblasts: Possible Applications in Glaucoma. [PDF]

Pharmaceuticals (Basel), 2023
Minnelli C, Piva F, Cecati M, Armeni T, Mobbili G, Galeazzi R, Melecchi A, Cristaldi M, Corsaro R, Rusciano D.   +9 more
europepmc   +1 more source

Meldonium as a supernosological drug

Consilium Medicum, 2020
openaire   +1 more source

Role of pFox inhibitors in the treatment of patients with acute myocardial ischemia

Терапевтический архив, 2014
AIM: To evaluate the anti-ischemic and anti-anginal efficacy of meldonium (Idrinol) in its short-term use as part of combination therapy in patients with chronic heart failure in the early post-infarction period/MATERIAL AND METHODS: The investigation ...
M E Statsenko, S V Turkina, N N Shilina
doaj