Results 51 to 60 of about 574 (170)

Cardiocytoprotection with metabolic drugs - study of the effectiveness of meldonium in ischemic heart disease [PDF]

, 2022
Summary Introduction. Ischemic heart disease is one of the most widespread cardiovascular diseases. In Republic of Moldova the total number of patients with ischemic heart disease is 30-40 thousand per 1 million population and is observed more of ...
Chetruș, Olga
core   +1 more source

Sports drug testing and the athletes' exposome

Drug Testing and Analysis, Volume 13, Issue 11-12, Page 1814-1821, November-December 2021., 2021
Investigations into the athlete's exposome and how to distinguish between deliberate drug use and different contamination scenarios has become a central topic of antidoping research, and a variety of challenges need to be taken into consideration. Abstract Similar to the general population, elite athletes are exposed to a complex set of environmental ...
Mario Thevis, Tiia Kuuranne, Matthew Fedoruk, Hans Geyer   +3 more
wiley   +1 more source

Unassisted Switchable Dual-Photoelectrode Devices Utilizing p-n Carbon Quantum Dots as "Semiconductor Electrolytes": Optimization Between H₂O₂ and Solar Electricity Production. [PDF]

Adv Sci (Weinh)
p‐n type carbon quantum dots (N‐CQDs) are designed as a conceptually‐new “semiconductor electrolyte” to develop a self‐driven photoelectrochemical cell that can be switched to optimize between H2O2 production and electricity generation under visible‐light illumination with water and O2 as reaction reagents.
Duan HM, Li CG, Mo LM, Dang JS, Jia XH, Yu JC, Mei YH, Thapper A, Wang HY.   +8 more
europepmc   +2 more sources

Carnitine and γ‐Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2‐mediated Transport [PDF]

, 2017
Publisher Copyright: © 2016 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society)Meldonium (3-(2,2,2-trimethylhydrazinium)propionate) is the most potent clinically used inhibitor of organic cation transporter 2 (OCTN2 ...
Helena Cirule, Dace Hartmane, Edgars Liepinsh, Liepinsh, Edgars, Eduards Sevostjanovs, Olga Zharkova‐Malkova, Elina Makarova, Grinberga, Solveiga, Sevostjanovs, Eduards, Solveiga Grinberga, Makarova, Elina, Maija Dambrova, Hartmane, Dace, Zharkova-Malkova, Olga, Cirule, Helena, Dambrova, Maija   +15 more
core   +1 more source

MELDONIUM: EFFECTIVE ACTION POINTS

Cardiovascular Therapy and Prevention, 2013
The paper is focused on hypoxia and cell ischemia as universal pathogenetic mechanisms of disease development, which can be addressed by both etiotropic and pathogenetic therapy. The latter is represented by the so-called metabolic correctors. At present, one of the most widely used metabolic correctors is mildronate.
A. L. Vertkin, N. O. Khovasova, V. V. Pshenichnikova, M. A. Alekseev, A. U. Abdullaeva   +4 more
openaire   +3 more sources

The Possibilities of Working Capacity Maintenance at Organophosphorous Compounds Intoxication

Вестник войск РХБ защиты, 2023
The experience of modern local armed conflicts and the monitoring of terrorist activity in the world indicate the possibility of the affection of people by organophosphorus compounds (OPs) in combat and as a result of industrial accidents and terrorist ...
A. Yu. Mikshta, L. P. Erdniev, A. A. Vlasov, I. V. Legotin, I. A. Ermolaeva, S. A. Komissarenko, I. A. Nelga   +6 more
doaj   +1 more source

Metformin Lowers Plasma Triacylglycerol Levels in Mice with Impaired Carnitine Biosynthesis and Fatty Liver

SynBio
The antidiabetic drug metformin has a wide range of metabolic effects and may also reduce the risk of obesity-related diseases. The aim of the current study was to investigate if metformin could counteract meldonium-induced fatty liver.
Bodil Bjørndal, Tra-My Thi Le, Elin Strand, Lise Madsen, Rolf K. Berge   +4 more
doaj   +1 more source

Meldonium use by athletes at the Baku 2015 European Games [PDF]

British Journal of Sports Medicine, 2016
BackgroundThe aim of this report was to estimate the prevalence of meldonium use in athletes competing in the Baku 2015 European Games to contribute to the surveillance of substances on the 2015 World Anti-Doping Agency (WADA) Monitoring Program. Meldonium is reported to be used by athletes to potentially enhance personal performance and shorten the ...
Mark, Stuart, Christian, Schneider, Klaus, Steinbach   +2 more
openaire   +2 more sources

USE OF MELDONIUM IN THE TREATMENT OF PATIENTS WITH CORONARY ARTERY DISEASE AND CONCOMITANT ARTERIAL HYPERTENSION

, 2019
Coronary artery disease (CAD) remains one of the leading causes of mortality and disability in Ukraine. Arterial hypertension (AH) is one of the most common diseases and a leading risk factor for coronary artery disease.The aim of the work is to evaluate
Volynskyi, Denys; Ivano-Frankivsk National Medical University, Vakaliuk, Ihor; Ivano-Frankivsk National Medical University   +1 more
core   +3 more sources

Influence of the cytoprotective drug meldonium on diastolic dysfunction of the myocardium [PDF]

, 2023
Background: The use of myocardial cytoprotectors (meldonium) in patients with exertional angina is a scientific-practical dilemma. Material and methods: An open randomized clinical trial was conducted involving 160 patients with chronic heart faliure ...
Istrati, Valeriu, Sasu, Diana, Chetruș, Olga, Gavriliuc, Svetlana, Calin, Ghenadie, Sârbu, Oxana   +5 more
core   +1 more source