SynBioThe antidiabetic drug metformin has a wide range of metabolic effects and may also reduce the risk of obesity-related diseases. The aim of the current study was to investigate if metformin could counteract meldonium-induced fatty liver.
Bodil Bjørndal +4 more
doaj +1 more source
Evaluation of cardioprotective effects of the incritinmimetics exenatideand vildagliptin in the experiment [PDF]
, 2017 The results of experimental and clinical trials make it clear that incretin mimetics possess pleiotropic effects and demonstrate the value in terms of assessment of their potential opportunities as cardioprotectors.
Danilenko, L. M. +4 more
core +2 more sources
A novel in vitro model for mature Toxoplasma gondii tissue cysts allows functional characterization of bradyzoite biology [PDF]
, 2023 Toxoplasma gondii bildet im Nerven- und Muskelgewebe seines Zwischenwirts persistente enzystierte Bradyzoiten, die Immunreaktionen und medizinischen Behandlungen entgehen.
Christiansen, Céline
core +1 more source
Meldonium (Mildronate): Primum nоn nocere
Pharmacological Research, 2016 [No abstract available]
openaire +4 more sources
Pharmacological screening of substances with cardioprotective effect in the group of 3-oxypyridine derivatives [PDF]
, 2018 Research objectives: To study the anti-hypoxic and cardioprotective effects of 3-oxypyridine derivatives. The search for compounds with an antihypoxic effect was carried out on blood leukocytes of rats in in ...
Danilenko, Lyudmila M. +5 more
core +2 more sources
Misuse of the metabolic modulator meldonium in sports
Journal of Sport and Health Science, 2017 Meldonium is currently claimed to be a relatively safe agent in patients needing anti-ischaemic therapy, but there is no compelling evidence that it may be effective in improving athletic performance, nor that its administration may be safe in healthy subjects.
LIPPI, Giuseppe, MATTIUZZI, Camilla
openaire +4 more sources
Pharmacological efficiency of statins and L-norvalin at an endotoxin-induced endothelial dysfunction [PDF]
, 2016 In the animals with endotoxin-induced endothelial dysfunction there were imbalance of contractile response of vessels wall observes when carrying out functional tests, increase of coefficient of endothelial dysfunction, decrease in contractility of a ...
Ivlitskaya, I. L. +2 more
core +2 more sources
Fluorescence chemosensing of meldonium using a cross-reactive sensor array
The Analyst, 2020 Differential sensing of meldonium was achieved using fluorescent chemosensors.
Ergin Yalcin +3 more
openaire +4 more sources
Nuclear factor kappa B as a potential target for pharmacological correction endothelium-associated pathology [PDF]
, 2017 The nuclear factor kappa B (NF-κB) is one of transcription factors. A high interest in studying the biological role of the signal system and its contribution to the development of cardiovascular, oncological and autoimmune diseases is obvious.
Burda, Y. E. +4 more
core +2 more sources
International Journal of Microbiology, Volume 2026, Issue 1, 2026.Atherosclerosis is an inflammatory process affecting the blood vessels, mainly the arteries. It is an established cause of a range of vascular disorders. Under homeostatic conditions, gut microbiota interacts with the host to affect its physiology and perform functions such as maintaining the integrity of the gut–epithelial barrier and immune ...
Saarim Bari +5 more
wiley +1 more source