Results 61 to 70 of about 1,036 (190)
Scientia Pharmaceutica, 2022 Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski +8 more
doaj +1 more source
Carnitine and γ-Butyrobetaine Stimulate Elimination of Meldonium due to Competition for OCTN2-mediated Transport [PDF]
, 2017 Publisher Copyright: © 2016 Nordic Association for the Publication of BCPT (former Nordic Pharmacological Society)Meldonium (3-(2,2,2-trimethylhydrazinium)propionate) is the most potent clinically used inhibitor of organic cation transporter 2 (OCTN2 ...
Bieber +31 more
core +1 more source
ANTI-ISCHEMIC AND ANTIOXIDANT ACTIVITY OF MELDONIUM IN IHD PATIENTS WITH STABLE ANGINA
Медицинский совет, 2016 (IHD), stable angina of effort of functional class II (43 persons) – III (39 persons) (53.3±7.5 y.o., men - 71, women - 11), with concomitant arterial hypertension – in 21 patient.
V. P. MIKHIN, P. Y. TYURIKOV
doaj +1 more source
Мелдониум и нейропротекция. Теория, эксперимент и клиническая практика [PDF]
, 2018 У цьому огляді розглянуті можливості корекції метаболізму при гострій ішемії мозку (ГІМ) шляхом активації стрес-лімітуючих систем при застосуванні вірогідного полімодального метаболічного коректора мелдоніуму.
Муслин, В.П. +1 more
core
Decreased long-chain acylcarnitine content increases mitochondrial coupling efficiency and prevents ischemia-induced brain damage in rats [PDF]
, 2023 Publisher Copyright: © 2023 The AuthorsLong-chain acylcarnitines (LCACs) are intermediates of fatty acid oxidation and are known to exert detrimental effects on mitochondria.
Dambrova, Maija +8 more
core +1 more source
Drug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
ChemMedChem, Volume 19, Issue 24, December 16, 2024.Inhibitors of the 2‐oxoglutarate (2OG)‐dependent hypoxia‐inducible factor prolyl hydroxylases (PHDs) are used for anemia treatment. Structures of the clinical PHD inhibitors Desidustat and Enarodustat complexed with the 2OG oxygenase factor inhibiting hypoxia‐inducible factor‐α (FIH) provide a basis to guide future PHD/2OG oxygenase inhibitor ...
Thomas P. Corner +9 more
wiley +1 more source
Oftalʹmologiâ, 2019 Purpose. Estimate of clinical efficacy of combined use of aflibercept and meldonium at tachyphylaxis of neovascular age-related macular degeneration (nAMD) to ranibizumab. Patients and methods. Comparative analysis of treatment results of nAMD in 25 eyes
N. S. Zhajvoronok +5 more
doaj +1 more source
Sports regulators and the potential for ‘breakaways’ [PDF]
, 2016 The commercially lucrative aspect of sport presents regulators with the threat of breakaways by entities focused on profits, which may not be in the best interest of the sport.
Boyes, S
core
Drug Testing and Analysis, Volume 16, Issue 7, Page 726-736, July 2024.Supercritical fluid chromatography‐mass spectrometry (SFC‐MS) was utilised for the analysis of various types of sample and, as such, has recently gained the attention of the anti‐doping community. We describe the analysis of almost 3000 anti‐doping samples using SFC‐MS instruments from Agilent Technologies, Waters Corporation and Shimadzu Corporation ...
Ivana Gavrilović +7 more
wiley +1 more source