Results 61 to 70 of about 364 (156)

Letter to Editor: Potential Use of Meldonium as Supportive Treatment in Lifestyle Diseases

open access: yesJournal of Education, Health and Sport
Meldonium, a drug more familiar in the sports world than in clinical medicine, acts as a structural analog of gamma-butyrobetaine and influences carnitine metabolism by inhibiting gamma-butyrobetaine hydroxylase. This results in reduced carnitine levels,
Magdalena Grzesiak, Oskar Szymański
doaj   +1 more source

Experience with mildronate in cerebrovascular diseases

open access: yesМедицинский совет, 2015
Over the past years, results of various clinical trials of drugs demonstrating their efficacy in the treatment of cardiovascular diseases have been published. The article discusses the results of clinical use of Mildronate (meldonium) in the treatment of
N. V. Pizova
doaj   +1 more source

Features of meldonium effect on the cells viability and mitochondria of blood leucocytes in patients with angina pectoris

open access: yesActa Biomedica Scientifica
Background. The ambiguous effectiveness of cardiocytoprotectors and the low level of evidence for their use in coronary heart disease (CHD) necessitate the study of their direct effect on cell viability for assessing cytoprotective activity.The aim.
A. L. Khokhlov   +4 more
doaj   +1 more source

Analysis of results of survey on disciplinary liability for use of athletes and methods prohibited from the perspective of contemporary challenges of sport

open access: yesJournal of Education, Health and Sport, 2017
This paper concerns the analysis of disciplinary responsibility of sportsman for doping. Responsibility for doping has a constructive character of disciplinary, but in exceptional circumstances, the nature of legal liability under the Penal Code.
Michał Nowak
doaj   +1 more source

Crystal structures of binary compounds of meldonium 3-(1,1,1-trimethylhydrazin-1-ium-2-yl)propanoate with sodium bromide and sodium iodide

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2018
3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate (C6H14N2O2, M, more commonly known under its commercial names Meldonium or Mildronate) co-crystalizes with sodium bromide and sodium iodide forming polymeric hydrates poly[[tetra-μ-aqua-diaquabis[3-(1,1,1 ...
Alexander Y Nazarenko
doaj   +1 more source

Аspects of pharmaceutical development of the combined medication of arginine and meldonium

open access: yesMedicine of Ukraine, 2015
З метою розробки нового комбінованого лікарського засобу, що поєднує аргінін та мельдоній у формі концентрату для інфузій, який запропонований для лікування метаболічних і функціональних системних розладів при захворюваннях серцево-судинної системи і цереброваскулярних захворюваннях, проведена фармацевтична розробка. На перших етапах розробки проведено
openaire   +3 more sources

Preventive cytoprotection in social diseases

open access: yesТерапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov   +4 more
doaj  

EFFECTIVENESS OF MELDONIUMIN IN CHRONIC HEART FAILURE PATIENTS

open access: yesМедицинский совет, 2017
This article discusses the relevance of the high mortality of cardiovascular diseases (CVD) and their complications. Provides an overview of research conducted in the field of treatment of chronic heart failure and other cardiovascular diseases.
G. N. Gorokhovskaya   +4 more
doaj   +1 more source

Chemoreactomic analysis of citrulline malate molecules

open access: yesНеврология, нейропсихиатрия, психосоматика, 2017
Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin   +4 more
doaj   +1 more source

Meldonium: drug which brought disrepute to sport

open access: yesInternational Journal of Basic & Clinical Pharmacology, 2017
World of sports have been rocked by doping scandals every now and then and World Anti-Doping Agency(WADA) has banned several offending drugs at different times to counter this menace. Meldonium is the recent addition to the long list of drugs banned by WADA to prevent its misuse among the athletes.
Bikash Ranjan Meher   +2 more
openaire   +2 more sources

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