Results 61 to 70 of about 364 (156)
Letter to Editor: Potential Use of Meldonium as Supportive Treatment in Lifestyle Diseases
Meldonium, a drug more familiar in the sports world than in clinical medicine, acts as a structural analog of gamma-butyrobetaine and influences carnitine metabolism by inhibiting gamma-butyrobetaine hydroxylase. This results in reduced carnitine levels,
Magdalena Grzesiak, Oskar Szymański
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Experience with mildronate in cerebrovascular diseases
Over the past years, results of various clinical trials of drugs demonstrating their efficacy in the treatment of cardiovascular diseases have been published. The article discusses the results of clinical use of Mildronate (meldonium) in the treatment of
N. V. Pizova
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Background. The ambiguous effectiveness of cardiocytoprotectors and the low level of evidence for their use in coronary heart disease (CHD) necessitate the study of their direct effect on cell viability for assessing cytoprotective activity.The aim.
A. L. Khokhlov +4 more
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This paper concerns the analysis of disciplinary responsibility of sportsman for doping. Responsibility for doping has a constructive character of disciplinary, but in exceptional circumstances, the nature of legal liability under the Penal Code.
Michał Nowak
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3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate (C6H14N2O2, M, more commonly known under its commercial names Meldonium or Mildronate) co-crystalizes with sodium bromide and sodium iodide forming polymeric hydrates poly[[tetra-μ-aqua-diaquabis[3-(1,1,1 ...
Alexander Y Nazarenko
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Аspects of pharmaceutical development of the combined medication of arginine and meldonium
З метою розробки нового комбінованого лікарського засобу, що поєднує аргінін та мельдоній у формі концентрату для інфузій, який запропонований для лікування метаболічних і функціональних системних розладів при захворюваннях серцево-судинної системи і цереброваскулярних захворюваннях, проведена фармацевтична розробка. На перших етапах розробки проведено
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Preventive cytoprotection in social diseases
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov +4 more
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EFFECTIVENESS OF MELDONIUMIN IN CHRONIC HEART FAILURE PATIENTS
This article discusses the relevance of the high mortality of cardiovascular diseases (CVD) and their complications. Provides an overview of research conducted in the field of treatment of chronic heart failure and other cardiovascular diseases.
G. N. Gorokhovskaya +4 more
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Chemoreactomic analysis of citrulline malate molecules
Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin +4 more
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Meldonium: drug which brought disrepute to sport
World of sports have been rocked by doping scandals every now and then and World Anti-Doping Agency(WADA) has banned several offending drugs at different times to counter this menace. Meldonium is the recent addition to the long list of drugs banned by WADA to prevent its misuse among the athletes.
Bikash Ranjan Meher +2 more
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