Results 61 to 70 of about 574 (170)

Exploring the Role of Gut Microbiota in Atherosclerosis and Novel Therapeutics to Mitigate the Disease Process—A Comprehensive Review of Current Literature

open access: yesInternational Journal of Microbiology, Volume 2026, Issue 1, 2026.
Atherosclerosis is an inflammatory process affecting the blood vessels, mainly the arteries. It is an established cause of a range of vascular disorders. Under homeostatic conditions, gut microbiota interacts with the host to affect its physiology and perform functions such as maintaining the integrity of the gut–epithelial barrier and immune ...
Saarim Bari   +5 more
wiley   +1 more source

Concepts for a New Rapid and Simple HPLC Method for Simultaneous Determination of Metoprolol and Meldonium in Pharmaceutical Dosage Forms

open access: yesScientia Pharmaceutica, 2022
Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski   +8 more
doaj   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

open access: yesDrug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis   +2 more
wiley   +1 more source

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat

open access: yesChemMedChem, Volume 19, Issue 24, December 16, 2024.
Inhibitors of the 2‐oxoglutarate (2OG)‐dependent hypoxia‐inducible factor prolyl hydroxylases (PHDs) are used for anemia treatment. Structures of the clinical PHD inhibitors Desidustat and Enarodustat complexed with the 2OG oxygenase factor inhibiting hypoxia‐inducible factor‐α (FIH) provide a basis to guide future PHD/2OG oxygenase inhibitor ...
Thomas P. Corner   +9 more
wiley   +1 more source

Structural and Functional Criteria of Neuroprotection Effectiveness after Anti-VEGF Therapy in Patients with Neovascular Age-Related Macular Degeneration

open access: yesOftalʹmologiâ, 2019
Purpose. Estimate of clinical efficacy of combined use of aflibercept and meldonium at tachyphylaxis of neovascular age-related macular degeneration (nAMD) to ranibizumab. Patients and methods. Comparative analysis of treatment results of nAMD in 25 eyes 
N. S. Zhajvoronok   +5 more
doaj   +1 more source

Routine application of SFC‐MS in doping control: Analysis of 3 × 1000 urine samples using three different SFC‐MS instruments

open access: yesDrug Testing and Analysis, Volume 16, Issue 7, Page 726-736, July 2024.
Supercritical fluid chromatography‐mass spectrometry (SFC‐MS) was utilised for the analysis of various types of sample and, as such, has recently gained the attention of the anti‐doping community. We describe the analysis of almost 3000 anti‐doping samples using SFC‐MS instruments from Agilent Technologies, Waters Corporation and Shimadzu Corporation ...
Ivana Gavrilović   +7 more
wiley   +1 more source

Study of Diluted Meldonium Solutions by Surface Enhanced Raman Scattering Spectroscopy [PDF]

open access: yes, 2019
Silvered porous silicon was utilized as an active substrate for a detection of small amounts of meldonium by surface enhanced Raman scattering (SERS) spectroscopy.
Bandarenka, H. V.   +5 more
core   +1 more source

What is the role of current mass spectrometry in pharmaceutical analysis?

open access: yesMass Spectrometry Reviews, Volume 43, Issue 3, Page 560-609, May/June 2024.
Abstract The role of mass spectrometry (MS) has become more important in most application domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation procedures, the need for good laboratory/manufacturing practices, and a large number of routine quality control analyses to be carried out.
Maria Khalikova   +5 more
wiley   +1 more source

Annual banned‐substance review 16th edition—Analytical approaches in human sports drug testing 2022/2023

open access: yesDrug Testing and Analysis, Volume 16, Issue 1, Page 5-29, January 2024.
Abstract In this 16th edition of the annual banned‐substance review on analytical approaches in human sports drug testing, literature on recent developments in this particular section of global anti‐doping efforts that was published between October 2022 and September 2023 is summarized and discussed.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Home - About - Disclaimer - Privacy