Results 81 to 90 of about 574 (170)

Preventive cytoprotection in social diseases

Терапевтический архив, 2015
Among many cytoprotective drugs, only a few of them that have a targeted metabolic effect include agents that partially inhibit oxidation of free fatty acids, the so-called p-FOX inhibitors (partial fatty acid oxidation inhibitors). Aim.
A S Skotnikov, G N Gorokhovskaya, A M Shilov, V L Yun, M A Khamurzova   +4 more
doaj  

Crystal structures of binary compounds of meldonium 3-(1,1,1-trimethylhydrazin-1-ium-2-yl)propanoate with sodium bromide and sodium iodide

Acta Crystallographica Section E: Crystallographic Communications, 2018
3-(1,1,1-Trimethylhydrazin-1-ium-2-yl)propanoate (C6H14N2O2, M, more commonly known under its commercial names Meldonium or Mildronate) co-crystalizes with sodium bromide and sodium iodide forming polymeric hydrates poly[[tetra-μ-aqua-diaquabis[3-(1,1,1 ...
Alexander Y Nazarenko
doaj   +1 more source

Development and validation of spectrophotometric method for the determination of meldonium dihydrate in dosage forms [PDF]

, 2018
Aim. Spectrophotometry is one of the most widely used methods in the pharmaceutical analysis. The main advantages of this absorption method are the highly sensitive, cost-effective and available to quality control laboratories for dosage forms.
Donchenko, Аnastasiia, Natalia Nahorna, Аnastasiia Donchenko, Svitlana Vasyuk, Vasyuk, Svitlana, Nahorna, Natalia   +5 more
core   +1 more source

The Effects of a Meldonium Pre-Treatment on the Sepsis-Induced Rat Heart Injury

, 2021
Background: Sepsis is a life-threatening condition caused by the dysregulated and overwhelming response to infection, accompanied by exaggerated pro-inflammatory state and lipid metabolism disturbance leading to sequential organ failure.1, 2 Meldonium is
Lakić, Iva, Stanković, Sanja, Grigorov, Ilijana, Đorđević, Jelena, Glumac, Sofija, Jasnić, Nebojša, Todorović, Zoran, Pavlović, Slađan, Đurović, Saša, Borković Mitić, Slavica, Tosti, Tomislav, Đurašević, Siniša, Ružičić, Aleksandra   +12 more
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EFFECTIVENESS OF MELDONIUMIN IN CHRONIC HEART FAILURE PATIENTS

Медицинский совет, 2017
This article discusses the relevance of the high mortality of cardiovascular diseases (CVD) and their complications. Provides an overview of research conducted in the field of treatment of chronic heart failure and other cardiovascular diseases.
G. N. Gorokhovskaya, V. L. Yoon, A. S. Skotnikov, A. I. Martynov, E. Yu. Maychuk   +4 more
doaj   +1 more source

Review of pharmacological characteristics of Meldonium. Use of it in sports as doping.

, 2018
Dissertação de Mestrado em Medicina do Desporto apresentada à Faculdade de MedicinaO Meldonium é um análogo estrutural do precursor da Carnitina, cujo mecanismo principal é inibir a síntese da Carnitina que é um transportador de FA do citoplasma para o ...
Yatsynych, Oksana
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Chemoreactomic analysis of citrulline malate molecules

Неврология, нейропсихиатрия, психосоматика, 2017
Citrulline malate that is essential for the biosynthesis of arginine promotes dehydration of ammonium endotoxins, by participating in the urea cycle. The indications for the use of citrulline malate are functional asthenia, asthenic syndrome, overfatigue,
I. Yu. Torshin, O. A. Gromova, L. E. Fedotova, A. N. Gromov, K. V. Rudakov   +4 more
doaj   +1 more source

The efficiency of metabolic impact of S-adenosylmethionine and meldonium on parameters of lipid profile and insulin resistance during comorbid course of nonalcocholic steatohepatitis, obesity and chronic kidney disease stage І-ІІ

Zaporožskij Medicinskij Žurnal, 2018
Objective – to investigate the influence of the complex of S-adenosylmethionine (Agepta) and meldonium (Vasonat) on the course of NASH with obesity and CKD, the state of the lipid profile of the blood, and the degree of insulin resistance.
O. S. Khukhlina, A. A. Antoniv, O. S. Voievidka, O. B. Kuzminska   +3 more
doaj   +1 more source

Post-COVID syndrome: status of carbohydrate metabolism in patients with hypertension and stable ischemic heart disease

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Post-COVID syndrome is associated with a wide range of chronic symptoms or conditions. Coronavirus di­sease 2019 (COVID-19) causes metabolic disorders such as hyperglycemia, insulin resistance.
O.V. Kuryata, O.S. Mytrokhina, Yu.S. Kushnir, O.I. Stadnyk   +3 more
doaj   +1 more source

Unsolved problems of cytoprotective therapy in patients with coronary heart disease

Терапевтический архив, 2015
The paper gives data on the proven efficiency of myocardial cytoprotection with the pFOX inhibitors trimetazidine and meldonium for coronary heart disease.
M E Statsenko, S V Turkina, A A Ermolenko   +2 more
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