Results 41 to 50 of about 364 (156)
The Effects of Meldonium on the Renal Acute Ischemia/Reperfusion Injury in Rats [PDF]
International Journal of Molecular Sciences, 2019 Acute renal ischemia/reperfusion (I/R) injury is a clinical condition that is challenging to treat. Meldonium is an anti-ischemic agent that shifts energy production from fatty acid oxidation to less oxygen-consuming glycolysis. Thus, in this study we investigated the effects of a four-week meldonium pre-treatment (300 mg/kg b.m./day) on acute renal I ...
Siniša Đurašević +11 more
openaire +7 more sources
International Journal of Microbiology, Volume 2026, Issue 1, 2026.Atherosclerosis is an inflammatory process affecting the blood vessels, mainly the arteries. It is an established cause of a range of vascular disorders. Under homeostatic conditions, gut microbiota interacts with the host to affect its physiology and perform functions such as maintaining the integrity of the gut–epithelial barrier and immune ...
Saarim Bari +5 more
wiley +1 more source
Scientia Pharmaceutica, 2022 Simultaneous determination of the tandem of drugs, like meldonium and metoprolol, with enormous polarity differences between them, requires thorough research and careful selection of chromatographic conditions.
Marjan Piponski +8 more
doaj +1 more source
Meldonium (Mildronate): Primum nоn nocere
Pharmacological Research, 2016 [No abstract available]
openaire +4 more sources
ANTI-ISCHEMIC AND ANTIOXIDANT ACTIVITY OF MELDONIUM IN IHD PATIENTS WITH STABLE ANGINA
Медицинский совет, 2016 (IHD), stable angina of effort of functional class II (43 persons) – III (39 persons) (53.3±7.5 y.o., men - 71, women - 11), with concomitant arterial hypertension – in 21 patient.
V. P. MIKHIN, P. Y. TYURIKOV
doaj +1 more source
Drug Testing and Analysis, Volume 17, Issue 8, Page 1417-1442, August 2025.Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario Thevis +2 more
wiley +1 more source
ChemMedChem, Volume 19, Issue 24, December 16, 2024.Inhibitors of the 2‐oxoglutarate (2OG)‐dependent hypoxia‐inducible factor prolyl hydroxylases (PHDs) are used for anemia treatment. Structures of the clinical PHD inhibitors Desidustat and Enarodustat complexed with the 2OG oxygenase factor inhibiting hypoxia‐inducible factor‐α (FIH) provide a basis to guide future PHD/2OG oxygenase inhibitor ...
Thomas P. Corner +9 more
wiley +1 more source
Oftalʹmologiâ, 2019 Purpose. Estimate of clinical efficacy of combined use of aflibercept and meldonium at tachyphylaxis of neovascular age-related macular degeneration (nAMD) to ranibizumab. Patients and methods. Comparative analysis of treatment results of nAMD in 25 eyes
N. S. Zhajvoronok +5 more
doaj +1 more source
Drug Testing and Analysis, Volume 16, Issue 7, Page 726-736, July 2024.Supercritical fluid chromatography‐mass spectrometry (SFC‐MS) was utilised for the analysis of various types of sample and, as such, has recently gained the attention of the anti‐doping community. We describe the analysis of almost 3000 anti‐doping samples using SFC‐MS instruments from Agilent Technologies, Waters Corporation and Shimadzu Corporation ...
Ivana Gavrilović +7 more
wiley +1 more source
What is the role of current mass spectrometry in pharmaceutical analysis?
Mass Spectrometry Reviews, Volume 43, Issue 3, Page 560-609, May/June 2024.Abstract The role of mass spectrometry (MS) has become more important in most application domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation procedures, the need for good laboratory/manufacturing practices, and a large number of routine quality control analyses to be carried out.
Maria Khalikova +5 more
wiley +1 more source